IL126702A0 - 2,4-Diaminopyrimidine derivatives - Google Patents

2,4-Diaminopyrimidine derivatives

Info

Publication number
IL126702A0
IL126702A0 IL12670297A IL12670297A IL126702A0 IL 126702 A0 IL126702 A0 IL 126702A0 IL 12670297 A IL12670297 A IL 12670297A IL 12670297 A IL12670297 A IL 12670297A IL 126702 A0 IL126702 A0 IL 126702A0
Authority
IL
Israel
Prior art keywords
diaminopyrimidine derivatives
diaminopyrimidine
derivatives
Prior art date
Application number
IL12670297A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL126702A0 publication Critical patent/IL126702A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12670297A 1996-05-15 1997-05-07 2,4-Diaminopyrimidine derivatives IL126702A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96107739 1996-05-15
PCT/EP1997/002355 WO1997043277A1 (en) 1996-05-15 1997-05-07 2,4-diaminopyrimidine derivatives

Publications (1)

Publication Number Publication Date
IL126702A0 true IL126702A0 (en) 1999-08-17

Family

ID=8222784

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12670297A IL126702A0 (en) 1996-05-15 1997-05-07 2,4-Diaminopyrimidine derivatives

Country Status (29)

Country Link
US (1) US5866583A (ko)
EP (1) EP0901488B1 (ko)
JP (1) JP3098259B2 (ko)
KR (1) KR100295509B1 (ko)
CN (1) CN1098260C (ko)
AR (1) AR007088A1 (ko)
AT (1) ATE227282T1 (ko)
AU (1) AU726416B2 (ko)
BR (1) BR9709251A (ko)
CA (1) CA2254117C (ko)
CO (1) CO4840509A1 (ko)
CY (1) CY2425B1 (ko)
CZ (1) CZ364698A3 (ko)
DE (1) DE69716901T2 (ko)
DK (1) DK0901488T3 (ko)
ES (1) ES2184089T3 (ko)
HR (1) HRP970260A2 (ko)
IL (1) IL126702A0 (ko)
MA (1) MA24182A1 (ko)
NO (1) NO985335L (ko)
NZ (1) NZ332481A (ko)
PE (1) PE78898A1 (ko)
PL (1) PL330277A1 (ko)
PT (1) PT901488E (ko)
TR (1) TR199802331T2 (ko)
TW (1) TW438796B (ko)
WO (1) WO1997043277A1 (ko)
YU (1) YU51498A (ko)
ZA (1) ZA973984B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0966464B1 (en) * 1997-03-03 2003-05-28 Basilea Pharmaceutica AG Substituted 2,4-diaminopyrimidines
PT966464E (pt) * 1997-03-03 2003-09-30 Basilea Pharmaceutica Ag 2,4-diaminopirimidinas substituidas
US6277860B1 (en) * 1999-10-29 2001-08-21 Pfizer Inc Furopyridine antibacterials
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
EP1633351A1 (en) * 2003-06-13 2006-03-15 Arena Pharmaceuticals, Inc. 5-substituted 2h-pyrazole-3-carboxylic acid derivatives as agonists for the nicotinic acid receptor rup25 for the treatment of dyslipidemia and related diseases
CA2534221A1 (en) * 2003-08-07 2005-02-24 Merck & Co., Inc. Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
DE102005062987A1 (de) * 2005-12-28 2007-07-05 Grünenthal GmbH Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
EP2185502A1 (en) * 2007-08-03 2010-05-19 F. Hoffmann-Roche AG Pyridinecarboxamide and benzamide derivatives as taar1 ligands
CN102224142B (zh) * 2008-11-21 2015-07-22 拉夸里亚创药株式会社 具有5-ht2b受体拮抗活性的新型吡唑-3-羧酰胺衍生物
US8716280B2 (en) * 2009-01-21 2014-05-06 Basilea Pharmaceutica Ag Bicyclic antibiotics
ES2437923T3 (es) * 2009-12-15 2014-01-15 Bayer Cropscience Ag Procedimiento para la preparación de derivados de ácido 1-alquil-/1-aril-5-pirazolcarboxílico
BR112013025792A2 (pt) 2011-04-05 2018-04-24 Pfizer Ltd Inibidores de quinase relacionada à pirrolo[2,3-d] pirimidina tropomisina
DE102013208484B4 (de) 2013-05-08 2018-04-26 Wirtgen Gmbh Vorrichtung zum Bearbeiten von Straßen- oder Bodenoberflächen, sowie Verfahren zum Lenken einer Straßenfräsmaschine
WO2020041556A1 (en) * 2018-08-22 2020-02-27 The Regents Of The University Of Colorado, A Body Corporate N-substituted-1h-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same
AR117169A1 (es) * 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
US4013644A (en) * 1976-03-15 1977-03-22 G. D. Searle & Co. [8 α(E), 13aβ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethenyl)-6H-dibenzo[a,g]quinolizines and intermediates thereto
US4444770A (en) * 1980-05-29 1984-04-24 Bayer Aktiengesellschaft New imidazoazole-alkenoic acid amide compounds, intermediate products for their production, their production, and their medicinal use
US4594199A (en) * 1983-09-19 1986-06-10 E. R. Squibb & Sons, Inc. Method for making phosphinic acid intermediates
JPH07509215A (ja) * 1990-11-14 1995-10-12 カイロン　コーポレイション ジヒドロ葉酸還元酵素の特異的阻害およびそのための化合物
DE69530104T2 (de) * 1994-11-24 2003-12-24 Basilea Pharmaceutica Ag, Basel Neue benzylpyrimidine
WO1996040640A1 (en) * 1995-06-07 1996-12-19 Pfizer Inc. BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION
TR199801014T2 (xx) * 1995-12-04 1998-09-21 F. Hoffmann-La Roche Ag. Diaminopirimidinler, bunlar� i�eren eczac�l�k kompozisyonlar� ve kullan�mlar�.

Also Published As

Publication number Publication date
CZ364698A3 (cs) 1999-02-17
ES2184089T3 (es) 2003-04-01
AU726416B2 (en) 2000-11-09
EP0901488A1 (en) 1999-03-17
AU2894297A (en) 1997-12-05
NO985335L (no) 1999-01-15
NZ332481A (en) 2000-04-28
PE78898A1 (es) 1998-11-13
YU51498A (en) 1999-11-22
US5866583A (en) 1999-02-02
JP3098259B2 (ja) 2000-10-16
CN1098260C (zh) 2003-01-08
WO1997043277A1 (en) 1997-11-20
CY2425B1 (en) 2004-11-12
MA24182A1 (fr) 1997-12-31
KR20000011053A (ko) 2000-02-25
ATE227282T1 (de) 2002-11-15
CA2254117A1 (en) 1997-11-20
TR199802331T2 (xx) 1999-04-21
HRP970260A2 (en) 1998-04-30
PT901488E (pt) 2003-03-31
JPH11511749A (ja) 1999-10-12
CO4840509A1 (es) 1999-09-27
ZA973984B (en) 1997-11-17
NO985335D0 (no) 1998-11-16
CA2254117C (en) 2003-03-11
CN1218465A (zh) 1999-06-02
TW438796B (en) 2001-06-07
DK0901488T3 (da) 2003-03-03
DE69716901D1 (de) 2002-12-12
EP0901488B1 (en) 2002-11-06
PL330277A1 (en) 1999-05-10
BR9709251A (pt) 1999-08-10
AR007088A1 (es) 1999-10-13
KR100295509B1 (ko) 2001-09-17
DE69716901T2 (de) 2003-09-18

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