IL126473A0 - 3-[(1, 2, 3, 4- tetrahydroisoquinolin- 2-yl) methyl]-8- azabicyclo [3.2.1] octane derivatives their preparation and their application in therapeutics - Google Patents
3-[(1, 2, 3, 4- tetrahydroisoquinolin- 2-yl) methyl]-8- azabicyclo [3.2.1] octane derivatives their preparation and their application in therapeuticsInfo
- Publication number
- IL126473A0 IL126473A0 IL12647397A IL12647397A IL126473A0 IL 126473 A0 IL126473 A0 IL 126473A0 IL 12647397 A IL12647397 A IL 12647397A IL 12647397 A IL12647397 A IL 12647397A IL 126473 A0 IL126473 A0 IL 126473A0
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydroisoquinolin
- azabicyclo
- therapeutics
- methyl
- preparation
- Prior art date
Links
- UECAYLDMIDGWPE-UHFFFAOYSA-N 2-(8-azabicyclo[3.2.1]octan-3-ylmethyl)-3,4-dihydro-1h-isoquinoline Chemical class C1CC2=CC=CC=C2CN1CC1CC(N2)CCC2C1 UECAYLDMIDGWPE-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9604565A FR2747386B1 (fr) | 1996-04-12 | 1996-04-12 | Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique |
| PCT/FR1997/000634 WO1997038998A1 (fr) | 1996-04-12 | 1997-04-10 | Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL126473A0 true IL126473A0 (en) | 1999-08-17 |
Family
ID=9491132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12647397A IL126473A0 (en) | 1996-04-12 | 1997-04-10 | 3-[(1, 2, 3, 4- tetrahydroisoquinolin- 2-yl) methyl]-8- azabicyclo [3.2.1] octane derivatives their preparation and their application in therapeutics |
Country Status (22)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2303851A1 (en) * | 2008-06-27 | 2011-04-06 | H. Lundbeck A/S | Novel phenolic and catecholic amines and prodrugs thereof |
| US10870660B2 (en) | 2016-07-28 | 2020-12-22 | Shionogi & Co., Ltd. | Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect |
| MX2020007849A (es) | 2018-01-26 | 2020-09-25 | Shionogi & Co | Compuesto ciclico condensado que tiene efecto antagonista del receptor de dopamina d3. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU895334D0 (en) * | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
| EP0306375A1 (fr) * | 1987-08-07 | 1989-03-08 | Synthelabo | Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique |
| IL89156A (en) * | 1988-07-12 | 1993-05-13 | Synthelabo | Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics |
| FR2661178B1 (fr) * | 1990-04-24 | 1993-03-12 | Synthelabo | Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique. |
-
1996
- 1996-04-12 FR FR9604565A patent/FR2747386B1/fr not_active Expired - Fee Related
-
1997
- 1997-04-10 CA CA002251335A patent/CA2251335A1/en not_active Abandoned
- 1997-04-10 CN CN97193750A patent/CN1216046A/zh active Pending
- 1997-04-10 SK SK1415-98A patent/SK141598A3/sk unknown
- 1997-04-10 KR KR1019980708123A patent/KR20000005392A/ko not_active Withdrawn
- 1997-04-10 AR ARP970101421A patent/AR008587A1/es unknown
- 1997-04-10 EE EE9800396A patent/EE9800396A/xx unknown
- 1997-04-10 PL PL97329243A patent/PL329243A1/xx unknown
- 1997-04-10 WO PCT/FR1997/000634 patent/WO1997038998A1/fr not_active Application Discontinuation
- 1997-04-10 EP EP97918195A patent/EP0892800A1/fr not_active Withdrawn
- 1997-04-10 NZ NZ332257A patent/NZ332257A/xx unknown
- 1997-04-10 CZ CZ983268A patent/CZ326898A3/cs unknown
- 1997-04-10 AU AU26409/97A patent/AU2640997A/en not_active Abandoned
- 1997-04-10 JP JP09536794A patent/JP2000512620A/ja active Pending
- 1997-04-10 TR TR1998/01839T patent/TR199801839T2/xx unknown
- 1997-04-10 BR BR9708654A patent/BR9708654A/pt not_active Application Discontinuation
- 1997-04-10 IL IL12647397A patent/IL126473A0/xx unknown
- 1997-04-10 TW TW086104625A patent/TW407158B/zh active
- 1997-04-11 CO CO97018806A patent/CO4900067A1/es unknown
- 1997-04-11 ZA ZA9703124A patent/ZA973124B/xx unknown
-
1998
- 1998-09-18 BG BG102779A patent/BG102779A/xx unknown
- 1998-10-09 NO NO984736A patent/NO984736L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ332257A (en) | 1999-03-29 |
| FR2747386B1 (fr) | 1998-05-15 |
| KR20000005392A (ko) | 2000-01-25 |
| AR008587A1 (es) | 2000-02-09 |
| CA2251335A1 (en) | 1997-10-23 |
| CN1216046A (zh) | 1999-05-05 |
| TW407158B (en) | 2000-10-01 |
| SK141598A3 (en) | 1999-03-12 |
| PL329243A1 (en) | 1999-03-15 |
| NO984736D0 (no) | 1998-10-09 |
| FR2747386A1 (fr) | 1997-10-17 |
| CZ326898A3 (cs) | 1999-01-13 |
| EE9800396A (et) | 1999-06-15 |
| BR9708654A (pt) | 1999-08-03 |
| CO4900067A1 (es) | 2000-03-27 |
| JP2000512620A (ja) | 2000-09-26 |
| TR199801839T2 (enrdf_load_stackoverflow) | 1998-12-21 |
| EP0892800A1 (fr) | 1999-01-27 |
| BG102779A (en) | 1999-09-30 |
| NO984736L (no) | 1998-11-23 |
| WO1997038998A1 (fr) | 1997-10-23 |
| AU2640997A (en) | 1997-11-07 |
| ZA973124B (en) | 1997-11-05 |
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