PL329243A1 - Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo [3.2.1] octane, their production and application in therapy - Google Patents

Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo [3.2.1] octane, their production and application in therapy

Info

Publication number
PL329243A1
PL329243A1 PL97329243A PL32924397A PL329243A1 PL 329243 A1 PL329243 A1 PL 329243A1 PL 97329243 A PL97329243 A PL 97329243A PL 32924397 A PL32924397 A PL 32924397A PL 329243 A1 PL329243 A1 PL 329243A1
Authority
PL
Poland
Prior art keywords
tetrahydroisoquinolin
azabicyclo
octane
therapy
derivatives
Prior art date
Application number
PL97329243A
Other languages
English (en)
Inventor
Mireille Sevrin
Benoit Marabout
Pascal George
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of PL329243A1 publication Critical patent/PL329243A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL97329243A 1996-04-12 1997-04-10 Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo [3.2.1] octane, their production and application in therapy PL329243A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
PL329243A1 true PL329243A1 (en) 1999-03-15

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
PL97329243A PL329243A1 (en) 1996-04-12 1997-04-10 Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo [3.2.1] octane, their production and application in therapy

Country Status (22)

Country Link
EP (1) EP0892800A1 (enrdf_load_stackoverflow)
JP (1) JP2000512620A (enrdf_load_stackoverflow)
KR (1) KR20000005392A (enrdf_load_stackoverflow)
CN (1) CN1216046A (enrdf_load_stackoverflow)
AR (1) AR008587A1 (enrdf_load_stackoverflow)
AU (1) AU2640997A (enrdf_load_stackoverflow)
BG (1) BG102779A (enrdf_load_stackoverflow)
BR (1) BR9708654A (enrdf_load_stackoverflow)
CA (1) CA2251335A1 (enrdf_load_stackoverflow)
CO (1) CO4900067A1 (enrdf_load_stackoverflow)
CZ (1) CZ326898A3 (enrdf_load_stackoverflow)
EE (1) EE9800396A (enrdf_load_stackoverflow)
FR (1) FR2747386B1 (enrdf_load_stackoverflow)
IL (1) IL126473A0 (enrdf_load_stackoverflow)
NO (1) NO984736L (enrdf_load_stackoverflow)
NZ (1) NZ332257A (enrdf_load_stackoverflow)
PL (1) PL329243A1 (enrdf_load_stackoverflow)
SK (1) SK141598A3 (enrdf_load_stackoverflow)
TR (1) TR199801839T2 (enrdf_load_stackoverflow)
TW (1) TW407158B (enrdf_load_stackoverflow)
WO (1) WO1997038998A1 (enrdf_load_stackoverflow)
ZA (1) ZA973124B (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2303851A1 (en) * 2008-06-27 2011-04-06 H. Lundbeck A/S Novel phenolic and catecholic amines and prodrugs thereof
US10870660B2 (en) 2016-07-28 2020-12-22 Shionogi & Co., Ltd. Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
MX2020007849A (es) 2018-01-26 2020-09-25 Shionogi & Co Compuesto ciclico condensado que tiene efecto antagonista del receptor de dopamina d3.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
NZ332257A (en) 1999-03-29
FR2747386B1 (fr) 1998-05-15
KR20000005392A (ko) 2000-01-25
AR008587A1 (es) 2000-02-09
CA2251335A1 (en) 1997-10-23
CN1216046A (zh) 1999-05-05
IL126473A0 (en) 1999-08-17
TW407158B (en) 2000-10-01
SK141598A3 (en) 1999-03-12
NO984736D0 (no) 1998-10-09
FR2747386A1 (fr) 1997-10-17
CZ326898A3 (cs) 1999-01-13
EE9800396A (et) 1999-06-15
BR9708654A (pt) 1999-08-03
CO4900067A1 (es) 2000-03-27
JP2000512620A (ja) 2000-09-26
TR199801839T2 (enrdf_load_stackoverflow) 1998-12-21
EP0892800A1 (fr) 1999-01-27
BG102779A (en) 1999-09-30
NO984736L (no) 1998-11-23
WO1997038998A1 (fr) 1997-10-23
AU2640997A (en) 1997-11-07
ZA973124B (en) 1997-11-05

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