IL126447A - An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis - Google Patents
An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosisInfo
- Publication number
- IL126447A IL126447A IL12644798A IL12644798A IL126447A IL 126447 A IL126447 A IL 126447A IL 12644798 A IL12644798 A IL 12644798A IL 12644798 A IL12644798 A IL 12644798A IL 126447 A IL126447 A IL 126447A
- Authority
- IL
- Israel
- Prior art keywords
- ldl
- active component
- density lipoprotein
- immunological
- hsp
- Prior art date
Links
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Paints Or Removers (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12644798A IL126447A (en) | 1998-10-04 | 1998-10-04 | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| CNB998140309A CN1176716C (zh) | 1998-10-04 | 1999-09-30 | 用于预防和/或治疗粥样动脉硬化的组合物 |
| AT99970026T ATE240115T1 (de) | 1998-10-04 | 1999-09-30 | Zusammensetzung zur vorbeugung und/oder behandlung der atherosklerose |
| SI9930342T SI1126867T1 (en) | 1998-10-04 | 1999-09-30 | A composition for the prevention and/or treatment of atherosclerosis |
| EP99970026A EP1126867B1 (fr) | 1998-10-04 | 1999-09-30 | Composition destinee a la prevention et/ou au traitement de l'atherosclerose |
| HU0104410A HUP0104410A3 (en) | 1998-10-04 | 1999-09-30 | A composition for the prevention and/or treatment of atherosclerosis |
| JP2000573378A JP4834219B2 (ja) | 1998-10-04 | 1999-09-30 | アテローム硬化症の予防および／または治療のための組成物 |
| AU59966/99A AU760582B2 (en) | 1998-10-04 | 1999-09-30 | A composition for the prevention and/or treatment of atherosclerosis |
| DE69907945T DE69907945T2 (de) | 1998-10-04 | 1999-09-30 | Zusammensetzung zur vorbeugung und/oder behandlung der atherosklerose |
| KR1020017004285A KR100680707B1 (ko) | 1998-10-04 | 1999-09-30 | 죽상경화증의 예방 및/또는 치료를 위한 조성물 |
| ES99970026T ES2198163T3 (es) | 1998-10-04 | 1999-09-30 | Composicion destinada a la prevencion y tratamiento de la ateroesclerosis. |
| US09/806,400 US20030114367A1 (en) | 1998-10-04 | 1999-09-30 | Composition for the prevention and/or treatment of artherosclerosis |
| CA2345445A CA2345445C (fr) | 1998-10-04 | 1999-09-30 | Composition destinee a la prevention et/ou au traitement de l'atherosclerose |
| DK99970026T DK1126867T3 (da) | 1998-10-04 | 1999-09-30 | Sammensætning til forebyggelse og/eller behandling af åreforkalkning |
| PT99970026T PT1126867E (pt) | 1998-10-04 | 1999-09-30 | Composicao para a prevencao e/ou tratamento da arteriosclerose. |
| BR9914631-2A BR9914631A (pt) | 1998-10-04 | 1999-09-30 | Composição imunológica oral indutora de tolerância para prevenção e/ou tratamento de enfermidades e método para prevenção e/ou tratamento de enfermidades |
| CNB2004100119407A CN100430090C (zh) | 1998-10-04 | 1999-09-30 | 用于预防和/或治疗粥样动脉硬化的组合物 |
| PCT/IL1999/000519 WO2000020019A2 (fr) | 1998-10-04 | 1999-09-30 | Composition destinee a la prevention et/ou au traitement de l'atherosclerose |
| US09/944,592 US20020025321A1 (en) | 1998-10-04 | 2001-09-04 | Composition for the prevention and/or treatment of atherosclerosis |
| HK05108561.7A HK1076600A1 (en) | 1998-10-04 | 2002-07-19 | A composition for the prevention and/or treatment of atherosclerosis |
| HK02105365A HK1043743A1 (en) | 1998-10-04 | 2002-07-19 | A composition for the prevention and/or treatment of atherosclerosis. |
| US10/989,724 US20050148499A1 (en) | 1998-10-04 | 2004-11-17 | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of atherosclerosis |
| US11/106,665 US20050197283A1 (en) | 1998-10-04 | 2005-04-15 | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12644798A IL126447A (en) | 1998-10-04 | 1998-10-04 | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126447A0 IL126447A0 (en) | 1999-08-17 |
| IL126447A true IL126447A (en) | 2004-09-27 |
Family
ID=11072009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12644798A IL126447A (en) | 1998-10-04 | 1998-10-04 | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20030114367A1 (fr) |
| EP (1) | EP1126867B1 (fr) |
| JP (1) | JP4834219B2 (fr) |
| KR (1) | KR100680707B1 (fr) |
| CN (2) | CN1176716C (fr) |
| AT (1) | ATE240115T1 (fr) |
| AU (1) | AU760582B2 (fr) |
| BR (1) | BR9914631A (fr) |
| CA (1) | CA2345445C (fr) |
| DE (1) | DE69907945T2 (fr) |
| DK (1) | DK1126867T3 (fr) |
| ES (1) | ES2198163T3 (fr) |
| HK (2) | HK1043743A1 (fr) |
| HU (1) | HUP0104410A3 (fr) |
| IL (1) | IL126447A (fr) |
| PT (1) | PT1126867E (fr) |
| WO (1) | WO2000020019A2 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100361933B1 (ko) * | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| US20050197283A1 (en) * | 1998-10-04 | 2005-09-08 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
| US7279459B2 (en) * | 2001-01-04 | 2007-10-09 | Vascular Biogenics Ltd. | Methods employing and compositions containing plaque associated molecules for prevention and treatment of atherosclerosis |
| US6458953B1 (en) * | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
| CA2313899A1 (fr) * | 1999-07-16 | 2001-01-16 | Enzo Therapeutics, Inc. | Nouveaux procedes de transplantation controles par une retro-regulation immunitaire selective, procedes pour prevenir ou traiter des maladies chez un sujet, et compositions comprenant des organes, des tissus ou des cellules programmes utiles pour l'etablissement d'une retro-regulation immunitaire selective |
| JP2004501061A (ja) * | 1999-12-15 | 2004-01-15 | ペプトル・リミテツド | 熱ショックタンパク質６０のフラグメントおよびアンタゴニスト |
| US6812205B2 (en) | 2000-03-15 | 2004-11-02 | The Brigham & Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
| FR2816060A1 (fr) * | 2000-10-27 | 2002-05-03 | Pf Medicament | Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules |
| GB0028122D0 (en) * | 2000-11-17 | 2001-01-03 | St Georges Entpr Ltd | Method |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US20030077279A1 (en) * | 2001-10-24 | 2003-04-24 | Cedars-Sinai Medical Center | Methods for treating vascular disease by inhibiting toll-like receptor-4 |
| AU2003273176A1 (en) * | 2002-05-17 | 2003-12-12 | Board Of Regents, The University Of Texas System | Beta-2-glycoprotein 1 is an inhibitor of angiogenesis |
| GB0226105D0 (en) * | 2002-11-08 | 2002-12-18 | St Georges S Entpr Ltd | Pain relief agents |
| US7264813B2 (en) * | 2003-09-24 | 2007-09-04 | Nikken Sohonsha Corporation | Therapeutic uses of Dunaliella powder |
| EP1676602A1 (fr) * | 2005-01-04 | 2006-07-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Administration continue d'épitopes derivés de protéinse présentes dans la plaque atèrosclérotique pour le traitement de l'athérosclérose |
| ES2565543T3 (es) * | 2005-01-24 | 2016-04-05 | Board Of Regents, The University Of Texas System | Construcciones de fusión a Fc de unión a fosfatidilserina y su uso terapéutico |
| JP2009515929A (ja) * | 2005-11-14 | 2009-04-16 | ネステク ソシエテ アノニム | 糖化タンパク質を用いた経口免疫寛容促進 |
| US8961982B2 (en) * | 2005-12-16 | 2015-02-24 | The Regents Of The University Of California | Modulation of developmental immune programming and protection against cardiovascular disease, diabetes, infectious diseases, and cancer |
| US8435538B2 (en) * | 2008-04-10 | 2013-05-07 | Thrombosis Research Institute | Anti-atheroma vaccine |
| WO2010033294A1 (fr) | 2008-09-22 | 2010-03-25 | Cedars-Sinai Medical Center | Md-2 humaine sous sa forme courte utilisée comme régulateur négatif de la signalisation par le récepteur de type toll-4 |
| US9512196B2 (en) | 2008-09-22 | 2016-12-06 | Cedars-Sinai Medical Center | Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling |
| CN103185801B (zh) * | 2011-12-30 | 2015-04-15 | 深圳市亚辉龙生物科技有限公司 | 一种检测抗β2糖蛋白I抗体的试剂装置及其方法 |
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| US7279459B2 (en) * | 2001-01-04 | 2007-10-09 | Vascular Biogenics Ltd. | Methods employing and compositions containing plaque associated molecules for prevention and treatment of atherosclerosis |
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-
1998
- 1998-10-04 IL IL12644798A patent/IL126447A/en not_active IP Right Cessation
-
1999
- 1999-09-30 DE DE69907945T patent/DE69907945T2/de not_active Expired - Lifetime
- 1999-09-30 BR BR9914631-2A patent/BR9914631A/pt not_active Application Discontinuation
- 1999-09-30 WO PCT/IL1999/000519 patent/WO2000020019A2/fr active IP Right Grant
- 1999-09-30 KR KR1020017004285A patent/KR100680707B1/ko not_active IP Right Cessation
- 1999-09-30 DK DK99970026T patent/DK1126867T3/da active
- 1999-09-30 CN CNB998140309A patent/CN1176716C/zh not_active Expired - Fee Related
- 1999-09-30 ES ES99970026T patent/ES2198163T3/es not_active Expired - Lifetime
- 1999-09-30 EP EP99970026A patent/EP1126867B1/fr not_active Expired - Lifetime
- 1999-09-30 US US09/806,400 patent/US20030114367A1/en not_active Abandoned
- 1999-09-30 PT PT99970026T patent/PT1126867E/pt unknown
- 1999-09-30 CA CA2345445A patent/CA2345445C/fr not_active Expired - Fee Related
- 1999-09-30 JP JP2000573378A patent/JP4834219B2/ja not_active Expired - Fee Related
- 1999-09-30 AT AT99970026T patent/ATE240115T1/de active
- 1999-09-30 AU AU59966/99A patent/AU760582B2/en not_active Ceased
- 1999-09-30 CN CNB2004100119407A patent/CN100430090C/zh not_active Expired - Fee Related
- 1999-09-30 HU HU0104410A patent/HUP0104410A3/hu unknown
-
2001
- 2001-09-04 US US09/944,592 patent/US20020025321A1/en not_active Abandoned
-
2002
- 2002-07-19 HK HK02105365A patent/HK1043743A1/xx not_active IP Right Cessation
- 2002-07-19 HK HK05108561.7A patent/HK1076600A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1126867B1 (fr) | 2003-05-14 |
| HUP0104410A2 (hu) | 2002-03-28 |
| DE69907945D1 (de) | 2003-06-18 |
| CA2345445C (fr) | 2010-08-24 |
| CN1616085A (zh) | 2005-05-18 |
| BR9914631A (pt) | 2001-07-03 |
| CN1176716C (zh) | 2004-11-24 |
| WO2000020019A3 (fr) | 2000-06-09 |
| IL126447A0 (en) | 1999-08-17 |
| WO2000020019A2 (fr) | 2000-04-13 |
| HUP0104410A3 (en) | 2004-07-28 |
| US20020025321A1 (en) | 2002-02-28 |
| JP2002526416A (ja) | 2002-08-20 |
| CN100430090C (zh) | 2008-11-05 |
| DK1126867T3 (da) | 2003-09-08 |
| ES2198163T3 (es) | 2004-01-16 |
| CN1332636A (zh) | 2002-01-23 |
| HK1076600A1 (en) | 2006-01-20 |
| AU760582B2 (en) | 2003-05-15 |
| ATE240115T1 (de) | 2003-05-15 |
| KR20010083886A (ko) | 2001-09-03 |
| JP4834219B2 (ja) | 2011-12-14 |
| PT1126867E (pt) | 2003-09-30 |
| HK1043743A1 (en) | 2002-09-27 |
| DE69907945T2 (de) | 2004-03-11 |
| AU5996699A (en) | 2000-04-26 |
| CA2345445A1 (fr) | 2000-04-13 |
| KR100680707B1 (ko) | 2007-02-08 |
| US20030114367A1 (en) | 2003-06-19 |
| EP1126867A2 (fr) | 2001-08-29 |
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