BR9914631A - Composição imunológica oral indutora de tolerância para prevenção e/ou tratamento de enfermidades e método para prevenção e/ou tratamento de enfermidades - Google Patents
Composição imunológica oral indutora de tolerância para prevenção e/ou tratamento de enfermidades e método para prevenção e/ou tratamento de enfermidadesInfo
- Publication number
- BR9914631A BR9914631A BR9914631-2A BR9914631A BR9914631A BR 9914631 A BR9914631 A BR 9914631A BR 9914631 A BR9914631 A BR 9914631A BR 9914631 A BR9914631 A BR 9914631A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- disease prevention
- tolerance
- low density
- prevention
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000006806 disease prevention Effects 0.000 title 2
- 230000001900 immune effect Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 102000007330 LDL Lipoproteins Human genes 0.000 abstract 2
- 108010007622 LDL Lipoproteins Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 102000006303 Chaperonin 60 Human genes 0.000 abstract 1
- 108010058432 Chaperonin 60 Proteins 0.000 abstract 1
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 abstract 1
- 101000738180 Euglena gracilis Chaperonin CPN60, mitochondrial Proteins 0.000 abstract 1
- 102000004895 Lipoproteins Human genes 0.000 abstract 1
- 108090001030 Lipoproteins Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
"COMPOSIçãO IMONOLóGICA ORAL INDUTORA DE TOLERâNCIA PARA PREVENçãO E/OU TRATAMENTO DE ENFERMIDADES E MéTODO PARA PREVENçãO E/OU TRATAMENTO DE ENFERMIDADES", compreendendo um componente ativo selecionado dentre o grupo consistente de lipoproteína modificada de baixa densidade, lipoproteína oxidada de baixa densidade (Ox LDL), proteína de choque térmico 60/65 (HSP 60/65), beta~ 2~-glicoproteína-1 (<225>~ 2~-GP-1), derivados funcionais e misturas das mesmas, em combinação com um veículo farmaceuticamente aceitável para administração oral.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12644798A IL126447A (en) | 1998-10-04 | 1998-10-04 | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
PCT/IL1999/000519 WO2000020019A2 (en) | 1998-10-04 | 1999-09-30 | A composition for the prevention and/or treatment of atherosclerosis |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9914631A true BR9914631A (pt) | 2001-07-03 |
Family
ID=11072009
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9914631-2A BR9914631A (pt) | 1998-10-04 | 1999-09-30 | Composição imunológica oral indutora de tolerância para prevenção e/ou tratamento de enfermidades e método para prevenção e/ou tratamento de enfermidades |
Country Status (17)
Country | Link |
---|---|
US (2) | US20030114367A1 (pt) |
EP (1) | EP1126867B1 (pt) |
JP (1) | JP4834219B2 (pt) |
KR (1) | KR100680707B1 (pt) |
CN (2) | CN100430090C (pt) |
AT (1) | ATE240115T1 (pt) |
AU (1) | AU760582B2 (pt) |
BR (1) | BR9914631A (pt) |
CA (1) | CA2345445C (pt) |
DE (1) | DE69907945T2 (pt) |
DK (1) | DK1126867T3 (pt) |
ES (1) | ES2198163T3 (pt) |
HK (2) | HK1076600A1 (pt) |
HU (1) | HUP0104410A3 (pt) |
IL (1) | IL126447A (pt) |
PT (1) | PT1126867E (pt) |
WO (1) | WO2000020019A2 (pt) |
Families Citing this family (23)
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KR100361933B1 (ko) * | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
US20050197283A1 (en) * | 1998-10-04 | 2005-09-08 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
US6458953B1 (en) * | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
JP4789311B2 (ja) * | 1999-07-16 | 2011-10-12 | エンゾー セラピューティクス, インコーポレイテッド | 新規の選択的免疫ダウンレギュレーション(sidr)媒介性移植プロセス、被験体における疾患を予防または処置するためのプロセス、およびsidrを確立するために有用である、馴化またはプログラミングされた細胞、組織または器官を含む組成物 |
CA2394504A1 (en) * | 1999-12-15 | 2001-06-21 | Peptor Ltd. | Fragments and antagonists of heat shock protein 60 |
US6812205B2 (en) | 2000-03-15 | 2004-11-02 | The Brigham & Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
FR2816060A1 (fr) * | 2000-10-27 | 2002-05-03 | Pf Medicament | Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules |
GB0028122D0 (en) * | 2000-11-17 | 2001-01-03 | St Georges Entpr Ltd | Method |
JP4191997B2 (ja) * | 2001-01-04 | 2008-12-03 | ヴァスキュラー バイオジェニックス リミテッド | アテローム性動脈硬化を防止および処置するために斑関連分子を用いる方法および斑関連分子を含有する組成物 |
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US20030077279A1 (en) * | 2001-10-24 | 2003-04-24 | Cedars-Sinai Medical Center | Methods for treating vascular disease by inhibiting toll-like receptor-4 |
WO2003099833A2 (en) * | 2002-05-17 | 2003-12-04 | Board Of Regents, The University Of Texas System | Beta-2-glycoprotein 1 is an inhibitor of angiogenesis |
GB0226105D0 (en) * | 2002-11-08 | 2002-12-18 | St Georges S Entpr Ltd | Pain relief agents |
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EP1676602A1 (en) * | 2005-01-04 | 2006-07-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis |
AU2006206187B2 (en) * | 2005-01-24 | 2011-03-10 | Board Of Regents, The University Of Texas System | Fc-fusion constructs binding to phosphatidylserine and their therapeutic use |
BRPI0618569A2 (pt) * | 2005-11-14 | 2011-09-06 | Nestec Sa | promoção de toleráncia oral com proteìnas glicadas |
US8961982B2 (en) * | 2005-12-16 | 2015-02-24 | The Regents Of The University Of California | Modulation of developmental immune programming and protection against cardiovascular disease, diabetes, infectious diseases, and cancer |
JP5654446B2 (ja) * | 2008-04-10 | 2015-01-14 | ザ・トロンボシス・リサーチ・インスティテュートThe Thrombosis Research Institute | 抗アテロームワクチン |
EP2328911A4 (en) | 2008-09-22 | 2012-03-14 | Cedars Sinai Medical Center | HUMAN MD-2 IN SHORT FORM AS NEGATIVE REGULATOR OF TOLL-4 TYPE RECEIVER SIGNALING |
US9512196B2 (en) | 2008-09-22 | 2016-12-06 | Cedars-Sinai Medical Center | Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling |
CN103185801B (zh) * | 2011-12-30 | 2015-04-15 | 深圳市亚辉龙生物科技有限公司 | 一种检测抗β2糖蛋白I抗体的试剂装置及其方法 |
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JP4191997B2 (ja) * | 2001-01-04 | 2008-12-03 | ヴァスキュラー バイオジェニックス リミテッド | アテローム性動脈硬化を防止および処置するために斑関連分子を用いる方法および斑関連分子を含有する組成物 |
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-
1998
- 1998-10-04 IL IL12644798A patent/IL126447A/en not_active IP Right Cessation
-
1999
- 1999-09-30 ES ES99970026T patent/ES2198163T3/es not_active Expired - Lifetime
- 1999-09-30 CA CA2345445A patent/CA2345445C/en not_active Expired - Fee Related
- 1999-09-30 PT PT99970026T patent/PT1126867E/pt unknown
- 1999-09-30 AT AT99970026T patent/ATE240115T1/de active
- 1999-09-30 US US09/806,400 patent/US20030114367A1/en not_active Abandoned
- 1999-09-30 DE DE69907945T patent/DE69907945T2/de not_active Expired - Lifetime
- 1999-09-30 BR BR9914631-2A patent/BR9914631A/pt not_active Application Discontinuation
- 1999-09-30 CN CNB2004100119407A patent/CN100430090C/zh not_active Expired - Fee Related
- 1999-09-30 WO PCT/IL1999/000519 patent/WO2000020019A2/en active IP Right Grant
- 1999-09-30 EP EP99970026A patent/EP1126867B1/en not_active Expired - Lifetime
- 1999-09-30 KR KR1020017004285A patent/KR100680707B1/ko not_active IP Right Cessation
- 1999-09-30 DK DK99970026T patent/DK1126867T3/da active
- 1999-09-30 JP JP2000573378A patent/JP4834219B2/ja not_active Expired - Fee Related
- 1999-09-30 CN CNB998140309A patent/CN1176716C/zh not_active Expired - Fee Related
- 1999-09-30 AU AU59966/99A patent/AU760582B2/en not_active Ceased
- 1999-09-30 HU HU0104410A patent/HUP0104410A3/hu unknown
-
2001
- 2001-09-04 US US09/944,592 patent/US20020025321A1/en not_active Abandoned
-
2002
- 2002-07-19 HK HK05108561.7A patent/HK1076600A1/xx not_active IP Right Cessation
- 2002-07-19 HK HK02105365A patent/HK1043743A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2345445C (en) | 2010-08-24 |
WO2000020019A3 (en) | 2000-06-09 |
HK1043743A1 (en) | 2002-09-27 |
KR100680707B1 (ko) | 2007-02-08 |
US20030114367A1 (en) | 2003-06-19 |
ES2198163T3 (es) | 2004-01-16 |
CN1332636A (zh) | 2002-01-23 |
CN100430090C (zh) | 2008-11-05 |
HUP0104410A3 (en) | 2004-07-28 |
AU5996699A (en) | 2000-04-26 |
KR20010083886A (ko) | 2001-09-03 |
IL126447A0 (en) | 1999-08-17 |
AU760582B2 (en) | 2003-05-15 |
US20020025321A1 (en) | 2002-02-28 |
EP1126867B1 (en) | 2003-05-14 |
JP2002526416A (ja) | 2002-08-20 |
IL126447A (en) | 2004-09-27 |
HK1076600A1 (en) | 2006-01-20 |
CA2345445A1 (en) | 2000-04-13 |
DE69907945D1 (de) | 2003-06-18 |
PT1126867E (pt) | 2003-09-30 |
WO2000020019A2 (en) | 2000-04-13 |
DE69907945T2 (de) | 2004-03-11 |
CN1616085A (zh) | 2005-05-18 |
ATE240115T1 (de) | 2003-05-15 |
DK1126867T3 (da) | 2003-09-08 |
JP4834219B2 (ja) | 2011-12-14 |
HUP0104410A2 (hu) | 2002-03-28 |
CN1176716C (zh) | 2004-11-24 |
EP1126867A2 (en) | 2001-08-29 |
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