IL125944A0 - Proton pump inhibitor - Google Patents
Proton pump inhibitorInfo
- Publication number
- IL125944A0 IL125944A0 IL12594497A IL12594497A IL125944A0 IL 125944 A0 IL125944 A0 IL 125944A0 IL 12594497 A IL12594497 A IL 12594497A IL 12594497 A IL12594497 A IL 12594497A IL 125944 A0 IL125944 A0 IL 125944A0
- Authority
- IL
- Israel
- Prior art keywords
- proton pump
- represent
- substituted
- compounds
- pump inhibitor
- Prior art date
Links
- 229940126409 proton pump inhibitor Drugs 0.000 title 1
- 239000000612 proton pump inhibitor Substances 0.000 title 1
- -1 3-substituted imidazo[1,2-d]-1,2,4-thiadiazoles Chemical class 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 102100021904 Potassium-transporting ATPase alpha chain 1 Human genes 0.000 abstract 1
- 102000006270 Proton Pumps Human genes 0.000 abstract 1
- 108010083204 Proton Pumps Proteins 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical class C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- JYZIHLWOWKMNNX-UHFFFAOYSA-N benzimidazole Chemical compound C1=C[CH]C2=NC=NC2=C1 JYZIHLWOWKMNNX-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 150000004867 thiadiazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/606,987 US5677302A (en) | 1996-02-26 | 1996-02-26 | Thiadiazole compounds useful as proton pump inhibitors |
PCT/CA1997/000125 WO1997031923A1 (fr) | 1996-02-26 | 1997-02-26 | Inhibiteur de pompe a protons |
Publications (1)
Publication Number | Publication Date |
---|---|
IL125944A0 true IL125944A0 (en) | 1999-04-11 |
Family
ID=24430335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12594497A IL125944A0 (en) | 1996-02-26 | 1997-02-26 | Proton pump inhibitor |
Country Status (21)
Country | Link |
---|---|
US (2) | US5677302A (fr) |
EP (1) | EP0883622B1 (fr) |
JP (1) | JPH11513993A (fr) |
KR (1) | KR19990087397A (fr) |
CN (1) | CN1216547A (fr) |
AT (1) | ATE217627T1 (fr) |
AU (1) | AU1762297A (fr) |
BR (1) | BR9707757A (fr) |
CA (1) | CA2247901A1 (fr) |
CZ (1) | CZ271298A3 (fr) |
DE (1) | DE69712608T2 (fr) |
DK (1) | DK0883622T3 (fr) |
ES (1) | ES2176675T3 (fr) |
HU (1) | HUP9901565A2 (fr) |
IL (1) | IL125944A0 (fr) |
NO (1) | NO983914L (fr) |
PL (1) | PL328863A1 (fr) |
PT (1) | PT883622E (fr) |
TR (1) | TR199801670T2 (fr) |
WO (1) | WO1997031923A1 (fr) |
YU (1) | YU42598A (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6852739B1 (en) * | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
US7365047B1 (en) * | 1999-09-28 | 2008-04-29 | The Regents Of The University Of California | Use of pentagastrin to inhibit gastric acid secretion or as a diuretic |
UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
CA2379375A1 (fr) * | 2002-03-28 | 2003-09-28 | Apotex Inc. | Derives sulfonamide d'imidazo-[1,2-d]-1,2,4-thiadiazoles substitues en position 3 et de [1,2,4]-thiadiazolo-[4,5-a]-benzimidazole substitue en position 3 employes comme inhibiteurs de la reticulation de la fibrine et de transglutaminases |
AU2003254282A1 (en) * | 2002-08-01 | 2004-02-23 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
MXPA04008070A (es) | 2003-03-10 | 2004-11-26 | Altana Pharma Ag | Novedoso proceso para la preparacion de roflumilasto. |
JP5383183B2 (ja) | 2005-03-16 | 2014-01-08 | タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロフルミラストを含有する矯味された剤形 |
US7803817B2 (en) * | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
US7981908B2 (en) * | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
JP5474541B2 (ja) * | 2006-07-25 | 2014-04-16 | ベクタ・リミテッド | 小さいジカルボン酸の誘導体と組み合わせてppiを用いる胃酸分泌を阻害する組成物および方法 |
US8653082B2 (en) * | 2009-02-25 | 2014-02-18 | Urifer Ltd. | 6-phenyl-2-[((piperidin-4-ylmethyl)-piperazin-1YL) or piperazin 1-ylmethyl)-piperidin-1-yl)]-imidazo[2,1-B][1,3,4]thiadiazole derivatives and their use |
CN110082487A (zh) * | 2019-05-13 | 2019-08-02 | 丽珠医药集团股份有限公司 | 检测试剂、检测系统及拉唑类药物肠吸收的试验方法 |
CN113880864A (zh) * | 2021-11-22 | 2022-01-04 | 吉首大学 | 含苯并咪唑骈杂硒咪唑亚胺的化合物及其制法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3864353A (en) * | 1973-12-17 | 1975-02-04 | Squibb & Sons Inc | 1-(1-Imidazolyl) (1,2,4) thiadiazolo (4,5-alpha) benzimidazoles |
US5106863A (en) * | 1990-03-26 | 1992-04-21 | Ortho Pharmaceutical Corporation | Substituted imidazole and pyridine derivatives |
DE4023215A1 (de) * | 1990-07-21 | 1992-01-23 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung |
-
1996
- 1996-02-26 US US08/606,987 patent/US5677302A/en not_active Expired - Fee Related
-
1997
- 1997-02-21 US US08/803,650 patent/US6093738A/en not_active Expired - Fee Related
- 1997-02-26 CN CN97193847A patent/CN1216547A/zh active Pending
- 1997-02-26 WO PCT/CA1997/000125 patent/WO1997031923A1/fr not_active Application Discontinuation
- 1997-02-26 YU YU42598A patent/YU42598A/sh unknown
- 1997-02-26 BR BR9707757-7A patent/BR9707757A/pt unknown
- 1997-02-26 PL PL97328863A patent/PL328863A1/xx unknown
- 1997-02-26 PT PT97903172T patent/PT883622E/pt unknown
- 1997-02-26 TR TR1998/01670T patent/TR199801670T2/xx unknown
- 1997-02-26 CZ CZ982712A patent/CZ271298A3/cs unknown
- 1997-02-26 HU HU9901565A patent/HUP9901565A2/hu unknown
- 1997-02-26 DK DK97903172T patent/DK0883622T3/da active
- 1997-02-26 CA CA002247901A patent/CA2247901A1/fr not_active Abandoned
- 1997-02-26 EP EP97903172A patent/EP0883622B1/fr not_active Expired - Lifetime
- 1997-02-26 AU AU17622/97A patent/AU1762297A/en not_active Abandoned
- 1997-02-26 AT AT97903172T patent/ATE217627T1/de not_active IP Right Cessation
- 1997-02-26 IL IL12594497A patent/IL125944A0/xx unknown
- 1997-02-26 JP JP9530480A patent/JPH11513993A/ja not_active Ceased
- 1997-02-26 ES ES97903172T patent/ES2176675T3/es not_active Expired - Lifetime
- 1997-02-26 KR KR1019980706813A patent/KR19990087397A/ko not_active Application Discontinuation
- 1997-02-26 DE DE69712608T patent/DE69712608T2/de not_active Expired - Fee Related
-
1998
- 1998-08-26 NO NO983914A patent/NO983914L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CN1216547A (zh) | 1999-05-12 |
NO983914D0 (no) | 1998-08-26 |
PL328863A1 (en) | 1999-03-01 |
ATE217627T1 (de) | 2002-06-15 |
BR9707757A (pt) | 2000-10-24 |
ES2176675T3 (es) | 2002-12-01 |
US5677302A (en) | 1997-10-14 |
DK0883622T3 (da) | 2002-09-09 |
PT883622E (pt) | 2002-09-30 |
DE69712608D1 (de) | 2002-06-20 |
KR19990087397A (ko) | 1999-12-27 |
NO983914L (no) | 1998-10-23 |
EP0883622A1 (fr) | 1998-12-16 |
HUP9901565A2 (hu) | 1999-08-30 |
JPH11513993A (ja) | 1999-11-30 |
WO1997031923A1 (fr) | 1997-09-04 |
US6093738A (en) | 2000-07-25 |
TR199801670T2 (xx) | 1998-11-23 |
DE69712608T2 (de) | 2002-08-29 |
CZ271298A3 (cs) | 1999-02-17 |
YU42598A (sh) | 2000-12-28 |
EP0883622B1 (fr) | 2002-05-15 |
CA2247901A1 (fr) | 1997-09-04 |
AU1762297A (en) | 1997-09-16 |
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