IL125800A0 - Thermally stabilized contrast agent - Google Patents

Thermally stabilized contrast agent

Info

Publication number
IL125800A0
IL125800A0 IL12580097A IL12580097A IL125800A0 IL 125800 A0 IL125800 A0 IL 125800A0 IL 12580097 A IL12580097 A IL 12580097A IL 12580097 A IL12580097 A IL 12580097A IL 125800 A0 IL125800 A0 IL 125800A0
Authority
IL
Israel
Prior art keywords
contrast agent
thermally stabilized
stabilized contrast
freeze
thermally
Prior art date
Application number
IL12580097A
Other languages
English (en)
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of IL125800A0 publication Critical patent/IL125800A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
IL12580097A 1996-02-19 1997-02-19 Thermally stabilized contrast agent IL125800A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Publications (1)

Publication Number Publication Date
IL125800A0 true IL125800A0 (en) 1999-04-11

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12580097A IL125800A0 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Country Status (18)

Country Link
EP (1) EP0885016B1 (zh)
JP (1) JP4250747B2 (zh)
KR (1) KR100501863B1 (zh)
CN (1) CN1092988C (zh)
AT (1) ATE237362T1 (zh)
AU (1) AU722735B2 (zh)
CA (1) CA2246778A1 (zh)
CZ (1) CZ262698A3 (zh)
DE (1) DE69720979T2 (zh)
EA (1) EA000900B1 (zh)
EE (1) EE9800248A (zh)
ES (1) ES2197331T3 (zh)
HU (1) HUP9900812A3 (zh)
IL (1) IL125800A0 (zh)
NO (1) NO313815B1 (zh)
NZ (1) NZ331372A (zh)
PL (1) PL328309A1 (zh)
WO (1) WO1997029782A1 (zh)

Families Citing this family (42)

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MXPA99001053A (es) * 1996-08-02 2002-03-11 Nycomed Imaging As Mejoramientos en o que se relacionan con agentes de contraste.
GB9717542D0 (en) * 1997-08-19 1997-10-22 Nycomed Imaging As Process
EP1308171A1 (en) 2000-07-13 2003-05-07 Daiichi Pharmaceutical Co., Ltd. Pharmaceutical compositions containing dds compounds
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
ATE299378T1 (de) * 2001-01-31 2005-07-15 Bracco Research Sa Lyophilisierbares kontrastmittel, gasgefüllte mikrobläschen enthaltend
WO2004049950A1 (en) 2002-11-29 2004-06-17 Amersham Health As Ultrasound triggering method
DK1590006T3 (da) * 2003-02-04 2010-12-20 Bracco Suisse Sa Ultralydskontrastmidler og fremgangsmåde til frembringelse deraf
JP5513708B2 (ja) 2003-12-22 2014-06-04 ブラッコ・シュイス・ソシエテ・アノニム 造影イメージング用の気体封入マイクロベシクル・アセンブリー
CN103120799A (zh) 2004-08-18 2013-05-29 博莱科瑞士股份有限公司 用于反差成像的充气微泡组合物
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
CA2662087C (en) 2006-09-05 2015-01-06 Bracco Research Sa Gas-filled microvesicles with polymer-modified lipids
EP2117603A2 (en) 2006-12-19 2009-11-18 Bracco International B.V. Targeting and therapeutic compounds and gas-filled microvesicles comprising said compounds
RU2010114029A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Астрессин и бета-эндорфин для применения в качестве терапевтических средств
CA2699222A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
JP5395794B2 (ja) 2007-09-11 2014-01-22 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのガラニンペプチドの使用
KR20100058555A (ko) 2007-09-11 2010-06-03 몬도바이오테크 래보래토리즈 아게 치료제로서의 ｂｐｐ－ｂ의 용도
AU2008303942A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of BFGF 1-24 and optionally (ARG 8) vasopressin to treat eg S. pneumoniae infection
US20100210538A1 (en) 2007-09-11 2010-08-19 Dorian Bevec Therapeutic uses of intermedin 47 and 53 peptides
WO2009033667A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2197465A2 (en) 2007-09-11 2010-06-23 Mondobiotech Laboratories AG Use of angiotensin ii as a therapeutic agent in the treatment of eg s. pneumoniae infection
KR20100059866A (ko) 2007-09-11 2010-06-04 몬도바이오테크 래보래토리즈 아게 Ｂ－타입 나트륨이뇨 펩티드 및 인간 성장 호르몬 １－４３의 치료적 용도
WO2009033746A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
KR20100061478A (ko) 2007-09-11 2010-06-07 몬도바이오테크 래보래토리즈 아게 치료제로서의 세크레틴 및 임의의 유로딜라틴의 용도
KR20100061679A (ko) 2007-09-11 2010-06-08 몬도바이오테크 래보래토리즈 아게 치료적 적용을 위한 티로트로핀 방출 호르몬
EP2090322A1 (en) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of fsh receptor ligands for diagnosis and therapy of cancer
CA2748995C (en) 2008-10-07 2018-01-16 Bracco Suisse Sa Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
BR112013003393B1 (pt) 2010-08-09 2021-07-13 Bracco Suisse Sa Suspensão aquosa compreendendo microvesícula cheia com gás e precursor da referida microvesícula
EP2426202A1 (en) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinases as targets for anti-diabetic therapy
CN103269717B (zh) 2010-12-24 2016-08-03 博莱科瑞士股份有限公司 气体填充微囊泡用作疫苗
DK2768484T3 (da) * 2011-10-21 2019-10-07 Jazz Pharmaceuticals Res Llc Lyofiliserede liposomer
EP2589383A1 (en) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin FKBP subtype-specific rapamycin analogue for use in treatment of diseases
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) * 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (en) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
BR112017011881A2 (pt) 2014-12-22 2018-01-02 Bracco Suisse Sa microvesículas cheias com gás para uso como vacina
CA3091952A1 (en) 2018-03-07 2019-09-12 Bracco Suisse Sa Preparation of size-controlled microvesicles
CN114007656A (zh) 2019-06-25 2022-02-01 博莱科瑞士股份有限公司 用于制备标准化充气微泡的冻干组合物
CN114025807A (zh) 2019-06-25 2022-02-08 博莱科瑞士股份有限公司 用于制备标准化充气微泡的冻干组合物
US10953023B1 (en) 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (en) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Antisense-oligonucleotides for prevention of kidney dysfunction promoted by endothelial dysfunction by ephrin-b2 suppression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
CN1092988C (zh) 2002-10-23
CZ262698A3 (cs) 1999-03-17
EA199800739A1 (ru) 1999-02-25
CA2246778A1 (en) 1997-08-21
EP0885016A1 (en) 1998-12-23
KR100501863B1 (ko) 2005-09-27
ATE237362T1 (de) 2003-05-15
HUP9900812A2 (hu) 1999-07-28
AU1805197A (en) 1997-09-02
AU722735B2 (en) 2000-08-10
JP4250747B2 (ja) 2009-04-08
EP0885016B1 (en) 2003-04-16
EA000900B1 (ru) 2000-06-26
ES2197331T3 (es) 2004-01-01
CN1213971A (zh) 1999-04-14
NO313815B1 (no) 2002-12-09
DE69720979T2 (de) 2004-02-26
HUP9900812A3 (en) 1999-11-29
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
JP2000506122A (ja) 2000-05-23
WO1997029782A1 (en) 1997-08-21
NZ331372A (en) 2000-01-28
NO983584L (no) 1998-10-16
DE69720979D1 (de) 2003-05-22
PL328309A1 (en) 1999-01-18
EE9800248A (et) 1999-02-15

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees