IL124511A - 2, 4, 7-trietherified-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens - Google Patents

2, 4, 7-trietherified-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens

Info

Publication number
IL124511A
IL124511A IL12451197A IL12451197A IL124511A IL 124511 A IL124511 A IL 124511A IL 12451197 A IL12451197 A IL 12451197A IL 12451197 A IL12451197 A IL 12451197A IL 124511 A IL124511 A IL 124511A
Authority
IL
Israel
Prior art keywords
viruses
chromogenic
acid
clinical
color
Prior art date
Application number
IL12451197A
Other languages
English (en)
Other versions
IL124511A0 (en
Original Assignee
Oklahoma Med Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma Med Res Found filed Critical Oklahoma Med Res Found
Publication of IL124511A0 publication Critical patent/IL124511A0/xx
Publication of IL124511A publication Critical patent/IL124511A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/027—Keto-aldonic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/50—Indoles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
IL12451197A 1996-09-25 1997-09-05 2, 4, 7-trietherified-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens IL124511A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/718,666 US5719020A (en) 1996-09-25 1996-09-25 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens
PCT/US1997/015602 WO1998013372A1 (en) 1996-09-25 1997-09-05 4,7-dialkoxy-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens

Publications (2)

Publication Number Publication Date
IL124511A0 IL124511A0 (en) 1998-12-06
IL124511A true IL124511A (en) 2002-08-14

Family

ID=24886990

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12451197A IL124511A (en) 1996-09-25 1997-09-05 2, 4, 7-trietherified-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens

Country Status (16)

Country Link
US (1) US5719020A (ja)
EP (1) EP0888371B1 (ja)
JP (1) JP4070817B2 (ja)
CN (2) CN1091447C (ja)
AT (1) ATE217879T1 (ja)
AU (1) AU716275B2 (ja)
BR (1) BR9706776A (ja)
CA (1) CA2237790A1 (ja)
DE (1) DE69712747T2 (ja)
ES (1) ES2173481T3 (ja)
HK (1) HK1016988A1 (ja)
IL (1) IL124511A (ja)
NO (1) NO310822B1 (ja)
NZ (1) NZ330443A (ja)
PL (1) PL327109A1 (ja)
WO (1) WO1998013372A1 (ja)

Families Citing this family (30)

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US6667161B1 (en) * 1997-10-27 2003-12-23 Ibbex, Inc. Chromogenic substrates of sialidase of bacterial, viral, protozoa, and vertebrate origin and methods of making and using the same
EP1038037A4 (en) * 1997-12-18 2003-02-12 Sepracor Inc DETERMINATION PROCEDURE FOR DETECTING AND DIAGNOSING THE INFLUENCE VIRUS
US6303764B1 (en) 1998-09-24 2001-10-16 Zymetx, Inc. Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
US6555698B1 (en) * 1998-11-17 2003-04-29 Tropix, Inc. Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor
WO2000063423A2 (en) * 1999-04-16 2000-10-26 Zymetx, Inc. Viral detection method using viral encoded enzymes and chemiluminescent substrates
US6420552B1 (en) 1999-09-10 2002-07-16 Zymetx, Inc. Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
US6627396B1 (en) * 1999-10-28 2003-09-30 The Regents Of The University Of California Influenza sensor
SE9904289D0 (sv) * 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
AU2003267949A1 (en) * 2002-03-15 2003-12-31 U.S. Government As Represented By The Department Of Veterans Affairs Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs
EA200500625A1 (ru) * 2002-10-10 2006-06-30 Дипартмент Оф Ветеранс Афэрс Обнаружение, локализация и определение стадий опухолей с помощью меченых активированных лимфоцитов, направленных на специфический опухолевый эпитоп
EA014533B1 (ru) * 2006-05-18 2010-12-30 Ветеринермедицинише Универзитет Вин Способы обнаружения вирусов гриппа
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US20090098527A1 (en) * 2006-09-12 2009-04-16 Fischer Gerald W Biological organism identification product and methods
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US9598462B2 (en) 2012-01-26 2017-03-21 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
CA2697373C (en) 2007-08-27 2019-05-21 Longhorn Vaccines & Diagnostics, Llc Immunogenic compositions and methods
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
EP3020832A1 (en) 2007-10-01 2016-05-18 Longhorn Vaccines and Diagnostics, LLC Biological specimen collection and transport system and methods of use
US9119866B2 (en) * 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
RU2713112C2 (ru) 2013-04-01 2020-02-03 Бектон, Дикинсон Энд Компани Способы и средства для диагностики гриппа
WO2016183292A1 (en) 2015-05-14 2016-11-17 Longhorn Vaccines And Diagnostics, Llc Rapid methods for the extraction of nucleic acids from biological samples
PL3516067T3 (pl) * 2016-09-19 2022-08-08 Julius-Maximilians-Universität Würzburg Związek i guma do żucia zawierająca ten związek do wykrywania wirusów za pomocą smaku
TWI631340B (zh) * 2017-06-16 2018-08-01 國立臺北科技大學 檢測神經胺酸酶活性的方法
CN107446004B (zh) * 2017-08-10 2020-05-01 济南山目生物医药科技有限公司 一种2-(4’-甲基伞形酮)-alpha-N-乙酰基神经氨酸钠的合成方法
US20220145407A1 (en) * 2019-03-05 2022-05-12 Japan Science And Technology Agency Method and kit for detecting influenza virus, and method for diagnosing influenza virus infection

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US3950322A (en) * 1973-08-27 1976-04-13 Research Corporation Fluorogenic substrate glycosides
JPS5925699A (ja) * 1982-08-03 1984-02-09 Torii Yakuhin Kk 酵素活性測定方法
JPS60164499A (ja) * 1984-02-07 1985-08-27 Kyowa Medetsukusu Kk 酵素活性測定法
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US5081017A (en) * 1986-02-18 1992-01-14 Texas Bioresource Corporation Method and apparatus for detection and quantitation of bacteria
US4810636A (en) * 1986-12-09 1989-03-07 Miles Inc. Chromogenic acridinone enzyme substrates
ES2097804T3 (es) * 1989-12-29 1997-04-16 Oklahoma Med Res Found Metodos para diagnosticar la gripe humana y sustratos cromogenos de acido n-acetilneuraminico para usar en estos metodos.
WO1991009971A1 (en) * 1990-01-05 1991-07-11 Symex Corp. Chromogenic 5-position modified neuraminic acid substrates and methods for diagnosing human influenza therewith
WO1991010744A1 (en) * 1990-01-10 1991-07-25 Symex Corp. Chromogenic 9-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith
AP249A (en) * 1990-04-24 1993-03-17 Biota Scient Management Pty Ltd Anti-viral compounds.
US5252485A (en) * 1990-08-10 1993-10-12 Savant Instruments, Inc. Unit for hydrolyzing amino-acid containing specimens
WO1992006691A1 (en) * 1990-10-19 1992-04-30 Biota Scientific Management Pty. Ltd. Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
US5252458A (en) * 1990-12-31 1993-10-12 Symex Corp. Method for visually detecting the presence of a virus in a clinical specimen
US5489675A (en) * 1992-06-25 1996-02-06 E. I. Du Pont De Nemours And Company Disaccharide sialidase substrates and inhibitors
US5556963A (en) * 1994-08-05 1996-09-17 Oklahoma Medical Research Foundation Synthesis of 4-alkoxy-N-acetylneuraminic acid

Also Published As

Publication number Publication date
ES2173481T3 (es) 2002-10-16
CA2237790A1 (en) 1998-04-02
EP0888371B1 (en) 2002-05-22
NZ330443A (en) 1998-12-23
BR9706776A (pt) 1999-05-18
DE69712747D1 (de) 2002-06-27
NO982343D0 (no) 1998-05-22
NO982343L (no) 1998-07-01
IL124511A0 (en) 1998-12-06
EP0888371A1 (en) 1999-01-07
CN1147589C (zh) 2004-04-28
AU4251297A (en) 1998-04-17
WO1998013372A1 (en) 1998-04-02
CN1324954A (zh) 2001-12-05
JP4070817B2 (ja) 2008-04-02
ATE217879T1 (de) 2002-06-15
CN1205011A (zh) 1999-01-13
NO310822B1 (no) 2001-09-03
JP2000501748A (ja) 2000-02-15
PL327109A1 (en) 1998-11-23
CN1091447C (zh) 2002-09-25
HK1016988A1 (en) 1999-11-12
US5719020A (en) 1998-02-17
AU716275B2 (en) 2000-02-24
DE69712747T2 (de) 2002-11-21

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Legal Events

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FF Patent granted
KB Patent renewed
RH1 Patent not in force