ATE217879T1 - 4,7-dialkoxy-n-acetylneuraminsaurederivate und methoden zur erkennung von influenza typ a und b in klinischen proben - Google Patents

4,7-dialkoxy-n-acetylneuraminsaurederivate und methoden zur erkennung von influenza typ a und b in klinischen proben

Info

Publication number
ATE217879T1
ATE217879T1 AT97940823T AT97940823T ATE217879T1 AT E217879 T1 ATE217879 T1 AT E217879T1 AT 97940823 T AT97940823 T AT 97940823T AT 97940823 T AT97940823 T AT 97940823T AT E217879 T1 ATE217879 T1 AT E217879T1
Authority
AT
Austria
Prior art keywords
dialkoxy
viruses
acid derivatives
clinical samples
substrates
Prior art date
Application number
AT97940823T
Other languages
English (en)
Inventor
Avraham Liav
Joyce Anne Hansjergen
Craig David Shimasaki
Original Assignee
Oklahoma Med Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma Med Res Found filed Critical Oklahoma Med Res Found
Application granted granted Critical
Publication of ATE217879T1 publication Critical patent/ATE217879T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02Acyclic radicals
    • C07H7/027Keto-aldonic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/50Indoles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
AT97940823T 1996-09-25 1997-09-05 4,7-dialkoxy-n-acetylneuraminsaurederivate und methoden zur erkennung von influenza typ a und b in klinischen proben ATE217879T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/718,666 US5719020A (en) 1996-09-25 1996-09-25 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens
PCT/US1997/015602 WO1998013372A1 (en) 1996-09-25 1997-09-05 4,7-dialkoxy-n-acetylneuraminic acid derivatives and methods for detection of influenza type a and b viruses in clinical specimens

Publications (1)

Publication Number Publication Date
ATE217879T1 true ATE217879T1 (de) 2002-06-15

Family

ID=24886990

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97940823T ATE217879T1 (de) 1996-09-25 1997-09-05 4,7-dialkoxy-n-acetylneuraminsaurederivate und methoden zur erkennung von influenza typ a und b in klinischen proben

Country Status (16)

Country Link
US (1) US5719020A (de)
EP (1) EP0888371B1 (de)
JP (1) JP4070817B2 (de)
CN (2) CN1091447C (de)
AT (1) ATE217879T1 (de)
AU (1) AU716275B2 (de)
BR (1) BR9706776A (de)
CA (1) CA2237790A1 (de)
DE (1) DE69712747T2 (de)
ES (1) ES2173481T3 (de)
HK (1) HK1016988A1 (de)
IL (1) IL124511A (de)
NO (1) NO310822B1 (de)
NZ (1) NZ330443A (de)
PL (1) PL327109A1 (de)
WO (1) WO1998013372A1 (de)

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US6667161B1 (en) * 1997-10-27 2003-12-23 Ibbex, Inc. Chromogenic substrates of sialidase of bacterial, viral, protozoa, and vertebrate origin and methods of making and using the same
CN1285003A (zh) * 1997-12-18 2001-02-21 塞普拉科有限公司 检测和诊断流感病毒的筛选方法
US6303764B1 (en) 1998-09-24 2001-10-16 Zymetx, Inc. Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
US6555698B1 (en) * 1998-11-17 2003-04-29 Tropix, Inc. Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor
AU4342100A (en) * 1999-04-16 2000-11-02 Zymetx, Inc. Viral detection method using viral encoded enzymes and chemiluminescent substrates
US6420552B1 (en) 1999-09-10 2002-07-16 Zymetx, Inc. Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
US6627396B1 (en) * 1999-10-28 2003-09-30 The Regents Of The University Of California Influenza sensor
SE9904289D0 (sv) * 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
WO2003077865A2 (en) * 2002-03-15 2003-09-25 Baxter International Inc. Methods and compositions for directing cells to target organs
BR0314471A (pt) * 2002-10-10 2005-08-02 Us Dept Veterans Affairs Detecção, localização e estadiamento de tumores usando linfócitos ativados classificados dirigidos a um epitopo especìfico do tumor
EP2018564B1 (de) * 2006-05-18 2010-05-12 Veterinärmedizinische Universität Wien Nachweisverfahren für grippeviren
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US20090098527A1 (en) * 2006-09-12 2009-04-16 Fischer Gerald W Biological organism identification product and methods
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
EP2772267B1 (de) 2007-08-27 2016-04-27 Longhorn Vaccines and Diagnostics, LLC Immunogene Zusammensetzungen und Verfahren
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
DK2535428T3 (en) 2007-10-01 2015-11-23 Longhorn Vaccines & Diagnostics Llc Biological prøvesamlings- and transport system, and methods of using
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
US9119866B2 (en) 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
CA3207612A1 (en) 2012-01-26 2013-08-01 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
CA2908028C (en) * 2013-04-01 2022-10-18 Becton, Dickinson And Company Methods and kits for the diagnosis of influenza
WO2016183292A1 (en) 2015-05-14 2016-11-17 Longhorn Vaccines And Diagnostics, Llc Rapid methods for the extraction of nucleic acids from biological samples
PL3516067T3 (pl) * 2016-09-19 2022-08-08 Julius-Maximilians-Universität Würzburg Związek i guma do żucia zawierająca ten związek do wykrywania wirusów za pomocą smaku
TWI631340B (zh) * 2017-06-16 2018-08-01 國立臺北科技大學 檢測神經胺酸酶活性的方法
CN107446004B (zh) * 2017-08-10 2020-05-01 济南山目生物医药科技有限公司 一种2-(4’-甲基伞形酮)-alpha-N-乙酰基神经氨酸钠的合成方法
US20220145407A1 (en) * 2019-03-05 2022-05-12 Japan Science And Technology Agency Method and kit for detecting influenza virus, and method for diagnosing influenza virus infection

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US3950322A (en) * 1973-08-27 1976-04-13 Research Corporation Fluorogenic substrate glycosides
JPS5925699A (ja) * 1982-08-03 1984-02-09 Torii Yakuhin Kk 酵素活性測定方法
JPS60164499A (ja) * 1984-02-07 1985-08-27 Kyowa Medetsukusu Kk 酵素活性測定法
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US5081017A (en) * 1986-02-18 1992-01-14 Texas Bioresource Corporation Method and apparatus for detection and quantitation of bacteria
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CA2072368C (en) * 1989-12-29 1998-06-30 Gregory A. Turner Methods for diagnosing human influenza and 4-position modified chromogenic n-acetylneuraminic acid substrates for use therein
WO1991009971A1 (en) * 1990-01-05 1991-07-11 Symex Corp. Chromogenic 5-position modified neuraminic acid substrates and methods for diagnosing human influenza therewith
AU7150891A (en) * 1990-01-10 1991-08-05 Symex Corp. Chromogenic 9-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith
CZ288492B6 (en) * 1990-04-24 2001-06-13 Biota Scient Management Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon
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WO1992006691A1 (en) * 1990-10-19 1992-04-30 Biota Scientific Management Pty. Ltd. Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
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US5489675A (en) * 1992-06-25 1996-02-06 E. I. Du Pont De Nemours And Company Disaccharide sialidase substrates and inhibitors
US5556963A (en) * 1994-08-05 1996-09-17 Oklahoma Medical Research Foundation Synthesis of 4-alkoxy-N-acetylneuraminic acid

Also Published As

Publication number Publication date
EP0888371A1 (de) 1999-01-07
CN1091447C (zh) 2002-09-25
DE69712747D1 (de) 2002-06-27
NZ330443A (en) 1998-12-23
PL327109A1 (en) 1998-11-23
NO310822B1 (no) 2001-09-03
JP2000501748A (ja) 2000-02-15
WO1998013372A1 (en) 1998-04-02
CN1205011A (zh) 1999-01-13
HK1016988A1 (en) 1999-11-12
IL124511A (en) 2002-08-14
CN1147589C (zh) 2004-04-28
JP4070817B2 (ja) 2008-04-02
NO982343D0 (no) 1998-05-22
CA2237790A1 (en) 1998-04-02
BR9706776A (pt) 1999-05-18
AU4251297A (en) 1998-04-17
NO982343L (no) 1998-07-01
CN1324954A (zh) 2001-12-05
US5719020A (en) 1998-02-17
IL124511A0 (en) 1998-12-06
AU716275B2 (en) 2000-02-24
DE69712747T2 (de) 2002-11-21
EP0888371B1 (de) 2002-05-22
ES2173481T3 (es) 2002-10-16

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