IL124375A - Stable biomolecular preparation that has undergone biotinylation and methods for its preparation - Google Patents

Stable biomolecular preparation that has undergone biotinylation and methods for its preparation

Info

Publication number
IL124375A
IL124375A IL12437596A IL12437596A IL124375A IL 124375 A IL124375 A IL 124375A IL 12437596 A IL12437596 A IL 12437596A IL 12437596 A IL12437596 A IL 12437596A IL 124375 A IL124375 A IL 124375A
Authority
IL
Israel
Prior art keywords
composition
biomolecule
biotinylated
biotin
enzyme
Prior art date
Application number
IL12437596A
Other languages
English (en)
Hebrew (he)
Other versions
IL124375A0 (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL124375A0 publication Critical patent/IL124375A0/xx
Publication of IL124375A publication Critical patent/IL124375A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
IL12437596A 1995-11-09 1996-10-24 Stable biomolecular preparation that has undergone biotinylation and methods for its preparation IL124375A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/555,602 US6551794B1 (en) 1995-11-09 1995-11-09 Stable biotinylated biomolecule composition
PCT/US1996/017200 WO1997017435A1 (fr) 1995-11-09 1996-10-24 Compositions stables a base de biomolecules biotinylees et leurs procedes d'utilisation

Publications (2)

Publication Number Publication Date
IL124375A0 IL124375A0 (en) 1998-12-06
IL124375A true IL124375A (en) 2002-04-21

Family

ID=24217905

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12437596A IL124375A (en) 1995-11-09 1996-10-24 Stable biomolecular preparation that has undergone biotinylation and methods for its preparation

Country Status (13)

Country Link
US (1) US6551794B1 (fr)
EP (1) EP0865486B1 (fr)
JP (2) JP2000514778A (fr)
AT (1) ATE312910T1 (fr)
AU (1) AU717383B2 (fr)
BR (1) BR9611430A (fr)
CA (1) CA2237357C (fr)
DE (1) DE69635584T2 (fr)
DK (1) DK0865486T3 (fr)
ES (1) ES2252761T3 (fr)
IL (1) IL124375A (fr)
NZ (1) NZ321443A (fr)
WO (1) WO1997017435A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW466116B (en) 1997-03-04 2001-12-01 Hayashibara Biochem Lab Reduction inhibitory agent for active-oxygen eliminating activity, method for inhibiting the reduction of said activity, and composition containing said agent
JP2001526027A (ja) * 1997-12-09 2001-12-18 ブリストル−マイヤーズ スクイブ カンパニー フィブリノーゲン変換酵素ハイブリド
US6187555B1 (en) 1998-04-16 2001-02-13 3M Innovative Properties Company Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
AU2001263200A1 (en) * 2000-05-17 2001-11-26 The American National Red Cross Gamma irradiation of protein-based pharmaceutical products
US6506365B1 (en) * 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
US20030068416A1 (en) * 2001-09-24 2003-04-10 Wilson Burgess Method of lyophylization to reduce solvent content and enhance product recovery
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
EP1852443A1 (fr) 2006-05-05 2007-11-07 Leukocare AG Matrice tridimensionelle biocompatible pour la immobilisation de substances biologiques
EP2058335B1 (fr) * 2007-11-07 2020-06-24 Leukocare Ag Matrice tridimensionnelle biocompatible pour l'immobilisation de substances biologiques
US20150299657A1 (en) * 2014-04-16 2015-10-22 General Electric Company Gamma stabilized dextran solutions and methods of use
US20160252434A1 (en) * 2014-04-16 2016-09-01 General Electric Company Gamma sterilized dextran solutions and methods of use
TWI590836B (zh) * 2012-05-14 2017-07-11 Teijin Ltd Radiation sterilization-resistant protein composition
CN103446600B (zh) * 2012-05-31 2020-05-22 通用电气公司 为含有葡萄糖氧化酶的膜杀菌的方法和相应的生物传感器
CN108064229B (zh) * 2015-03-12 2021-12-28 三洋化成工业株式会社 蛋白质组合物的制造方法和蛋白质组合物
CN112852666A (zh) * 2021-01-19 2021-05-28 新疆河润水业有限责任公司 一种微生物菌剂的制备方法及采用微生物菌剂制备的微生物肥料

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3779706A (en) * 1971-10-04 1973-12-18 Energy Sciences Inc Process for bulk sterilization, minimizing chemical and physical damage
GB8331514D0 (en) 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
DE3583940D1 (de) 1984-10-02 1991-10-02 Harry M Meade Herstellung von streptavidinaehnlichen polypeptiden.
IL76234A0 (en) 1985-08-28 1986-01-31 Yeda Res & Dev New biotinylation reagents
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4897346A (en) * 1986-07-15 1990-01-30 Beckman Instruments, Inc. Stabilized liquid enzyme composition for glucose determination
US4794082A (en) 1987-02-17 1988-12-27 Hoechst Celanese Corporation Biotinylating agents
US4798795A (en) 1987-02-17 1989-01-17 Hoechst Celanese Corporation Biotinylating agents
US4709037A (en) 1987-02-17 1987-11-24 Hoechst Celanese Corporation Biotinylating agents
JPS63246382A (ja) 1987-04-02 1988-10-13 Karupisu Shokuhin Kogyo Kk ビオチニル試薬及びそれを用いるビオチニル化法
US5043288A (en) 1988-06-20 1991-08-27 Motsenbocker Marvin A Immobilize molecular binding partners to contact activating supports
FR2638099B1 (fr) 1988-10-20 1991-01-25 Immunotech Sa Immunoadsorbant a faible taux de relargage et son procede d'obtention
US4897364A (en) 1989-02-27 1990-01-30 Motorola, Inc. Method for locos isolation using a framed oxidation mask and a polysilicon buffer layer
US5026785A (en) 1989-05-12 1991-06-25 The United States Of America As Represented By The Department Of Health And Human Services Avidin and streptavidin modified water-soluble polymers such as polyacrylamide, and the use thereof in the construction of soluble multivalent macromolecular conjugates
JPH05331071A (ja) * 1992-01-17 1993-12-14 Asahi Chem Ind Co Ltd カルシトニン遺伝子関連ペプチド類の凍結乾燥組成物および安定化法
US5306824A (en) 1992-04-15 1994-04-26 Georgia Tech Research Corporation Biotinylated isocoumarins
CN1091315A (zh) 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
JP3007785B2 (ja) * 1993-03-16 2000-02-07 旭化成工業株式会社 トロンボモジュリン組成物およびその変性防止方法
EP0731834B1 (fr) 1993-12-03 2000-05-24 Buckman Laboratories International, Inc. Stabilisation d'enzymes par des copolymeres sequences
JPH07194378A (ja) 1993-12-28 1995-08-01 Fuji Seito Kk トレハロースによる酵素の安定化法
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
CA2222035A1 (fr) * 1995-04-11 1997-03-27 Trustees Of Boston University Proteines mutantes de streptavidine
US5691152A (en) * 1995-11-09 1997-11-25 E. R. Squibb & Sons, Inc. Stable avidin composition

Also Published As

Publication number Publication date
ES2252761T3 (es) 2006-05-16
DE69635584T2 (de) 2006-09-21
JP2007295936A (ja) 2007-11-15
EP0865486B1 (fr) 2005-12-14
EP0865486A1 (fr) 1998-09-23
NZ321443A (en) 2000-01-28
DK0865486T3 (da) 2006-02-06
AU717383B2 (en) 2000-03-23
ATE312910T1 (de) 2005-12-15
US6551794B1 (en) 2003-04-22
WO1997017435A1 (fr) 1997-05-15
IL124375A0 (en) 1998-12-06
EP0865486A4 (fr) 2002-06-26
DE69635584D1 (de) 2006-01-19
AU7477796A (en) 1997-05-29
BR9611430A (pt) 1999-06-29
CA2237357C (fr) 2002-07-30
JP2000514778A (ja) 2000-11-07
CA2237357A1 (fr) 1997-05-15

Similar Documents

Publication Publication Date Title
JP2007295936A (ja) 安定なビオチン化生体分子の組成物及び方法
US5998155A (en) Stable composition of immobilized protein having affinity for biotin
CA2235243C (fr) Preparations et procedes pour stabiliser des materiaux biologiques a l'aide de procedes de dessiccation sans congelation
JPH02265984A (ja) 物質の貯蔵
US5219749A (en) Process for isolating and preparing purified chitin deacetylase
US5770194A (en) Fibrin sealant compositions and methods for utilizing same
US3711574A (en) Copolymers of acrylamide gas
Lee et al. Oligomeric structure of the multifunctional protein CAD that initiates pyrimidine biosynthesis in mammalian cells.
RU2074891C1 (ru) Способ доочистки химопапаина
Larsen et al. Polymerization of Penicillins: V. Separation, identification and quantitative determination of Antigenic Polymerization products in Ampicillin Sodium preparations by high-performance liquid chromatography
CN112972662B (zh) 一种蛋白酶k的冻干保护剂及制备方法和应用
Yamazaki et al. Isolation and characterization of a protein subunit of broad bean mottle virus
RU2054044C1 (ru) Способ получения рекомбинантного человеческого свободного от метионина на n-конце гамма-интерферона
King et al. Reaction of tobacco mosaic virus with maleic anhydride and some possible applications to X-ray diffraction analysis
JPS6027517B2 (ja) その場で重合させて蛋白質を固定化する方法
EP0367302A2 (fr) Procédé pour la semi-synthèse d'insuline humaine protéase I d'Achromobacter réticulée soluble dans l'eau pour sa mise en oeuvre et procédé pour la préparation de celle-ci
JPH0757760B2 (ja) 生体由来物質の固定化方法
Lindsay et al. Spore resistance and the basic mechanism of heat resistance
Berre et al. Some characteristics of the coagulation Factor X a purified from human serum
JP2004163423A (ja) 血液凝固促進剤及び血液検査用容器
JPS59206314A (ja) 血液製剤中の病原体不活化法
RU1838407C (ru) Способ получени химопапаина
DE1935711A1 (de) Wasserunloesliches,traegergebundenes Protein
Karsakevich et al. Immobilization of the enzyme L-asparaginase of E. coli on polysaccharides. V. Preparation and properties of polymeric conjugates based on water-soluble CM-cellulose differing by the quantitative amounts of polymer
Richardson THE AMINO ACID SEQUENCE OF THE

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees