DK0865486T3 - Stabilt biotinyleret biomolekylepræparat og fremgangsmåder - Google Patents

Stabilt biotinyleret biomolekylepræparat og fremgangsmåder

Info

Publication number
DK0865486T3
DK0865486T3 DK96937005T DK96937005T DK0865486T3 DK 0865486 T3 DK0865486 T3 DK 0865486T3 DK 96937005 T DK96937005 T DK 96937005T DK 96937005 T DK96937005 T DK 96937005T DK 0865486 T3 DK0865486 T3 DK 0865486T3
Authority
DK
Denmark
Prior art keywords
methods
compositions
stable
biomolecule
protectant
Prior art date
Application number
DK96937005T
Other languages
Danish (da)
English (en)
Inventor
Steven J Burton
James C Pearson
Peter A D Edwardson
Alan Menzies
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK0865486T3 publication Critical patent/DK0865486T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK96937005T 1995-11-09 1996-10-24 Stabilt biotinyleret biomolekylepræparat og fremgangsmåder DK0865486T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/555,602 US6551794B1 (en) 1995-11-09 1995-11-09 Stable biotinylated biomolecule composition

Publications (1)

Publication Number Publication Date
DK0865486T3 true DK0865486T3 (da) 2006-02-06

Family

ID=24217905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96937005T DK0865486T3 (da) 1995-11-09 1996-10-24 Stabilt biotinyleret biomolekylepræparat og fremgangsmåder

Country Status (13)

Country Link
US (1) US6551794B1 (fr)
EP (1) EP0865486B1 (fr)
JP (2) JP2000514778A (fr)
AT (1) ATE312910T1 (fr)
AU (1) AU717383B2 (fr)
BR (1) BR9611430A (fr)
CA (1) CA2237357C (fr)
DE (1) DE69635584T2 (fr)
DK (1) DK0865486T3 (fr)
ES (1) ES2252761T3 (fr)
IL (1) IL124375A (fr)
NZ (1) NZ321443A (fr)
WO (1) WO1997017435A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW466116B (en) 1997-03-04 2001-12-01 Hayashibara Biochem Lab Reduction inhibitory agent for active-oxygen eliminating activity, method for inhibiting the reduction of said activity, and composition containing said agent
EP1037969A4 (fr) * 1997-12-09 2003-05-21 Bristol Myers Squibb Co Hybrides d'enzymes de conversion du fibrinogene
US6187555B1 (en) 1998-04-16 2001-02-13 3M Innovative Properties Company Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
WO2001087357A2 (fr) * 2000-05-17 2001-11-22 The American National Red Cross Irradiation gamma de produits pharmaceutiques a base de proteine
US6506365B1 (en) * 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
US20030068416A1 (en) * 2001-09-24 2003-04-10 Wilson Burgess Method of lyophylization to reduce solvent content and enhance product recovery
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
EP1852443A1 (fr) 2006-05-05 2007-11-07 Leukocare AG Matrice tridimensionelle biocompatible pour la immobilisation de substances biologiques
EP2058335B1 (fr) * 2007-11-07 2020-06-24 Leukocare Ag Matrice tridimensionnelle biocompatible pour l'immobilisation de substances biologiques
US20150299657A1 (en) * 2014-04-16 2015-10-22 General Electric Company Gamma stabilized dextran solutions and methods of use
US20160252434A1 (en) * 2014-04-16 2016-09-01 General Electric Company Gamma sterilized dextran solutions and methods of use
IN2014DN09624A (fr) * 2012-05-14 2015-07-31 Teijin Ltd
CN103446600B (zh) * 2012-05-31 2020-05-22 通用电气公司 为含有葡萄糖氧化酶的膜杀菌的方法和相应的生物传感器
JP6951243B2 (ja) * 2015-03-12 2021-10-20 三洋化成工業株式会社 タンパク質組成物の製造方法及びタンパク質組成物
CN112852666A (zh) * 2021-01-19 2021-05-28 新疆河润水业有限责任公司 一种微生物菌剂的制备方法及采用微生物菌剂制备的微生物肥料

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3779706A (en) * 1971-10-04 1973-12-18 Energy Sciences Inc Process for bulk sterilization, minimizing chemical and physical damage
GB8331514D0 (en) 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
WO1986002077A1 (fr) 1984-10-02 1986-04-10 Meade Harry M Production de polypeptides analogues a la streptavidine
IL76234A0 (en) 1985-08-28 1986-01-31 Yeda Res & Dev New biotinylation reagents
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4897346A (en) * 1986-07-15 1990-01-30 Beckman Instruments, Inc. Stabilized liquid enzyme composition for glucose determination
US4709037A (en) 1987-02-17 1987-11-24 Hoechst Celanese Corporation Biotinylating agents
US4794082A (en) 1987-02-17 1988-12-27 Hoechst Celanese Corporation Biotinylating agents
US4798795A (en) 1987-02-17 1989-01-17 Hoechst Celanese Corporation Biotinylating agents
JPS63246382A (ja) 1987-04-02 1988-10-13 Karupisu Shokuhin Kogyo Kk ビオチニル試薬及びそれを用いるビオチニル化法
US5043288A (en) 1988-06-20 1991-08-27 Motsenbocker Marvin A Immobilize molecular binding partners to contact activating supports
FR2638099B1 (fr) 1988-10-20 1991-01-25 Immunotech Sa Immunoadsorbant a faible taux de relargage et son procede d'obtention
US4897364A (en) 1989-02-27 1990-01-30 Motorola, Inc. Method for locos isolation using a framed oxidation mask and a polysilicon buffer layer
US5026785A (en) 1989-05-12 1991-06-25 The United States Of America As Represented By The Department Of Health And Human Services Avidin and streptavidin modified water-soluble polymers such as polyacrylamide, and the use thereof in the construction of soluble multivalent macromolecular conjugates
JPH05331071A (ja) * 1992-01-17 1993-12-14 Asahi Chem Ind Co Ltd カルシトニン遺伝子関連ペプチド類の凍結乾燥組成物および安定化法
US5306824A (en) 1992-04-15 1994-04-26 Georgia Tech Research Corporation Biotinylated isocoumarins
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
JP3007785B2 (ja) * 1993-03-16 2000-02-07 旭化成工業株式会社 トロンボモジュリン組成物およびその変性防止方法
ATE193319T1 (de) 1993-12-03 2000-06-15 Buckman Labor Inc Enzymstabilisierung durch blockcopolymere
JPH07194378A (ja) 1993-12-28 1995-08-01 Fuji Seito Kk トレハロースによる酵素の安定化法
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
WO1997011183A1 (fr) * 1995-04-11 1997-03-27 Trustees Of Boston University Proteines mutantes de streptavidine
US5691152A (en) * 1995-11-09 1997-11-25 E. R. Squibb & Sons, Inc. Stable avidin composition

Also Published As

Publication number Publication date
AU7477796A (en) 1997-05-29
ATE312910T1 (de) 2005-12-15
EP0865486A4 (fr) 2002-06-26
DE69635584T2 (de) 2006-09-21
IL124375A0 (en) 1998-12-06
NZ321443A (en) 2000-01-28
ES2252761T3 (es) 2006-05-16
WO1997017435A1 (fr) 1997-05-15
AU717383B2 (en) 2000-03-23
DE69635584D1 (de) 2006-01-19
EP0865486B1 (fr) 2005-12-14
US6551794B1 (en) 2003-04-22
JP2007295936A (ja) 2007-11-15
BR9611430A (pt) 1999-06-29
CA2237357C (fr) 2002-07-30
EP0865486A1 (fr) 1998-09-23
CA2237357A1 (fr) 1997-05-15
JP2000514778A (ja) 2000-11-07
IL124375A (en) 2002-04-21

Similar Documents

Publication Publication Date Title
DK0865486T3 (da) Stabilt biotinyleret biomolekylepræparat og fremgangsmåder
BG103977A (en) Low molecular rotamase enzymic activity inhibitors
CA2227901A1 (fr) Adjuvant ameliore pour ciment
CA2405716A1 (fr) Nouvelles compositions chimiquement modifiees de proteines stimulant erythropoietine et procedes
AU5060900A (en) Chemically modified lipolytic enzyme
CA2159055A1 (fr) Compositions contenant des polysaccharides polyanioniques et des polymeres bioabsorbables hydrophobes
CA2273064A1 (fr) Nouveaux processus pour amplifier de l'acide nucleique, processus de marquage post-terminaison pour la determination des sequences nucleotidiques et production d'acides nucleiquesa stabilite thermodynamique reduite
AU1803601A (en) Methods and compositions for the introduction of molecules into cells
MXPA00006887A (es) Compuestos de polimero-pigmento.
NO992167D0 (no) Preparater og fremgangsmÕter for immobilisering av nukleinsyrer til faste bµrere
GB2337051A (en) Process for making maleic anhydride polymers which include maleamic acid and/or its cyclic imide repeat units
CA2273078A1 (fr) Utilisation d'acides nucleiques lies a des macromolecules porteuses
DE69922880D1 (de) Enzymzusammensetzungen, die in vivo Oligosaccharide bilden können
HUP0202434A2 (en) Flocculation of cell material
WO2001021760A3 (fr) Fioles rotatives de culture de cellules
AU2831900A (en) Stereocomplex hydrogels
AU3101300A (en) Compositions containing alpha-sulfofatty acid esters and methods of making and using the same
AU2001266638A1 (en) Compositions containing alpha-sulfofatty acid esters and methods of making the same
AU5297999A (en) Use of a composition
IL138688A0 (en) Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
ES2007245A6 (es) Metodo para producir nuevas composiciones secas que contienen polisacaridos, asi como composicion y producto alimenticio.
NO974545L (no) Eksopolysakkaridnedbrytende enzym, og anvendelse av samme
ES2181897T3 (es) Composicion enzimatica.
HUP9801439A2 (hu) Béta-D-Galakotpiranozil-D-xilózok alkalmazása bél laktáz kimutatására alkalmas készítmények és oldatok előállításánál, valamint eljárás a vegyületek előállítására
AU2787400A (en) Compositions and methods for modulating growth or differentiation of growth-factor dependent cells