IL121969A - 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds - Google Patents

10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds

Info

Publication number
IL121969A
IL121969A IL12196997A IL12196997A IL121969A IL 121969 A IL121969 A IL 121969A IL 12196997 A IL12196997 A IL 12196997A IL 12196997 A IL12196997 A IL 12196997A IL 121969 A IL121969 A IL 121969A
Authority
IL
Israel
Prior art keywords
trioxatricyclo
pentadecanone
derivatives
compounds
preparation
Prior art date
Application number
IL12196997A
Other languages
English (en)
Other versions
IL121969A0 (en
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of IL121969A0 publication Critical patent/IL121969A0/xx
Publication of IL121969A publication Critical patent/IL121969A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
IL12196997A 1996-10-24 1997-10-14 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds IL121969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19644195A DE19644195A1 (de) 1996-10-24 1996-10-24 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IL121969A0 IL121969A0 (en) 1998-03-10
IL121969A true IL121969A (en) 2000-06-29

Family

ID=7809858

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12196997A IL121969A (en) 1996-10-24 1997-10-14 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds

Country Status (27)

Country Link
US (1) US5912235A (ja)
EP (1) EP0838469B1 (ja)
JP (1) JP4175682B2 (ja)
KR (1) KR100466495B1 (ja)
CN (1) CN1093133C (ja)
AR (1) AR009809A1 (ja)
AT (1) ATE211745T1 (ja)
AU (1) AU726092B2 (ja)
BR (2) BR9705143A (ja)
CA (1) CA2219311C (ja)
CZ (1) CZ291768B6 (ja)
DE (2) DE19644195A1 (ja)
DK (1) DK0838469T3 (ja)
DZ (1) DZ2322A1 (ja)
ES (1) ES2170318T3 (ja)
HK (1) HK1010885A1 (ja)
HU (1) HU222540B1 (ja)
IL (1) IL121969A (ja)
MX (1) MX9707974A (ja)
NO (1) NO308362B1 (ja)
NZ (1) NZ328979A (ja)
PL (1) PL184693B1 (ja)
PT (1) PT838469E (ja)
RU (1) RU2181727C2 (ja)
SK (1) SK283114B6 (ja)
UA (1) UA44310C2 (ja)
ZA (1) ZA979059B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998023629A1 (fr) * 1996-11-26 1998-06-04 Chugai Seiyaku Kabushiki Kaisha Composes de macrolides comportant une chaine a 13 elements, medicament les contenant et leur procede de preparation
PT1489090E (pt) * 2000-08-17 2006-05-31 Kitasato Inst Novos derivados de pseudoeritromicina
JP2003007917A (ja) * 2001-06-19 2003-01-10 Sanyo Electric Co Ltd 回路装置の製造方法
US6986882B2 (en) * 2002-01-17 2006-01-17 Astrazeneca Ab Therapy for functional dyspepsia
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
GB0611907D0 (en) 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
JP2009501199A (ja) 2005-07-12 2009-01-15 グラクソ グループ リミテッド Gpr38アゴニストとしてのピペラジンヘテロアリール誘導体
MX2008001211A (es) 2005-07-26 2008-03-24 Glaxo Group Ltd Derivados de bencilpiperazina y su uso medico.
CA2632779A1 (en) * 2005-12-08 2007-06-14 Pfizer Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
DE602007006019D1 (de) 2006-06-28 2010-06-02 Glaxo Group Ltd Für die behandlung von durch den gpr38-rezeptor vermittelten krankheiten geeignete piperazinylderivate
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス, インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
RU2533116C2 (ru) 2009-02-27 2014-11-20 Раквалиа Фарма Инк. Оксииндольные производные, обладающие агонистической активностью в отношении мотилинового рецептора
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NZ328979A (en) 1998-10-28
CN1093133C (zh) 2002-10-23
JPH10130297A (ja) 1998-05-19
BR9705157A (pt) 1999-09-28
CZ291768B6 (cs) 2003-05-14
JP4175682B2 (ja) 2008-11-05
ATE211745T1 (de) 2002-01-15
CA2219311C (en) 2007-09-04
CN1186808A (zh) 1998-07-08
US5912235A (en) 1999-06-15
NO974934D0 (no) 1997-10-24
SK283114B6 (sk) 2003-02-04
PT838469E (pt) 2002-05-31
HU222540B1 (hu) 2003-08-28
HK1010885A1 (en) 1999-07-02
HU9701660D0 (en) 1997-12-29
PL322802A1 (en) 1998-04-27
DE19644195A1 (de) 1998-04-30
KR100466495B1 (ko) 2005-05-27
CA2219311A1 (en) 1998-04-24
AR009809A1 (es) 2000-05-03
HUP9701660A2 (hu) 1998-05-28
KR19980032626A (ko) 1998-07-25
AU4278897A (en) 1998-04-30
DE59705964D1 (de) 2002-02-14
EP0838469A1 (de) 1998-04-29
NO308362B1 (no) 2000-09-04
RU2181727C2 (ru) 2002-04-27
MX9707974A (es) 1998-04-30
ZA979059B (en) 1998-05-07
DZ2322A1 (fr) 2002-12-28
UA44310C2 (uk) 2002-02-15
DK0838469T3 (da) 2002-03-18
PL184693B1 (pl) 2002-12-31
SK141997A3 (en) 1998-05-06
BR9705143A (pt) 2000-12-12
HUP9701660A3 (en) 1998-08-28
ES2170318T3 (es) 2002-08-01
IL121969A0 (en) 1998-03-10
EP0838469B1 (de) 2002-01-09
NO974934L (no) 1998-04-27
AU726092B2 (en) 2000-11-02
CZ310697A3 (cs) 1998-06-17

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IL121969A (en) 10,13,15-trioxatricyclo¬9.2.1.1.9.6¾-pentadecanone derivatives their preparation and pharmaceutical compositions containing these compounds

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees