IL114808A - Combinations of protease inhibitors for the treatment of hiv infection and aids - Google Patents
Combinations of protease inhibitors for the treatment of hiv infection and aidsInfo
- Publication number
- IL114808A IL114808A IL11480895A IL11480895A IL114808A IL 114808 A IL114808 A IL 114808A IL 11480895 A IL11480895 A IL 11480895A IL 11480895 A IL11480895 A IL 11480895A IL 114808 A IL114808 A IL 114808A
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- aids
- protease inhibitors
- combinations
- hiv
- Prior art date
Links
- 208000031886 HIV Infections Diseases 0.000 title 1
- 208000037357 HIV infectious disease Diseases 0.000 title 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004030 hiv protease inhibitor Substances 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 229940122440 HIV protease inhibitor Drugs 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229940042443 other antivirals in atc Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28947494A | 1994-08-11 | 1994-08-11 | |
| US33936994A | 1994-11-14 | 1994-11-14 | |
| US49246195A | 1995-07-20 | 1995-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL114808A0 IL114808A0 (en) | 1995-12-08 |
| IL114808A true IL114808A (en) | 1999-10-28 |
Family
ID=27403895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11480895A IL114808A (en) | 1994-08-11 | 1995-08-02 | Combinations of protease inhibitors for the treatment of hiv infection and aids |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0774969B8 (no) |
| JP (1) | JPH10504036A (no) |
| KR (1) | KR970704441A (no) |
| CN (1) | CN1101190C (no) |
| AT (1) | ATE232727T1 (no) |
| AU (1) | AU698664B2 (no) |
| CA (1) | CA2197207C (no) |
| CY (1) | CY2360B1 (no) |
| CZ (1) | CZ292577B6 (no) |
| DE (1) | DE69529678T2 (no) |
| DK (1) | DK0774969T3 (no) |
| ES (1) | ES2190456T3 (no) |
| FI (1) | FI970565A (no) |
| HU (1) | HUT76540A (no) |
| IL (1) | IL114808A (no) |
| MX (1) | MX9701121A (no) |
| NO (1) | NO314168B1 (no) |
| PL (1) | PL181578B1 (no) |
| SK (1) | SK18197A3 (no) |
| WO (1) | WO1996004913A1 (no) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA49803C2 (uk) * | 1994-06-03 | 2002-10-15 | Дж.Д. Сьорль Енд Ко | Спосіб лікування ретровірусних інфекцій |
| US6037157A (en) * | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
| CA2270546A1 (en) * | 1996-11-08 | 1998-05-22 | Japan Energy Corporation | Aids remedy |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US517041A (en) * | 1894-03-27 | Fruit-picker | ||
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| CA2096408C (en) * | 1990-11-19 | 2005-02-08 | Gary Anthony Decrescenzo | Retroviral protease inhibitors |
| DE69132423T2 (de) * | 1990-11-19 | 2001-04-26 | Monsanto Co | Inhibitoren retroviraler Proteasen |
| IE913840A1 (en) * | 1990-11-20 | 1992-05-20 | Abbott Lab | Retroviral protease inhibiting compounds |
| SG52731A1 (en) * | 1991-11-08 | 1998-09-28 | Merck & Co Inc | Hiv protease inhibitors useful for the treatment of aids |
| PT727419E (pt) * | 1992-12-29 | 2002-08-30 | Abbott Lab | Compostos intermediarios para a preparacao de inibidores da protease retroviral |
-
1995
- 1995-08-02 IL IL11480895A patent/IL114808A/xx not_active IP Right Cessation
- 1995-08-07 HU HU9700402A patent/HUT76540A/hu unknown
- 1995-08-07 JP JP8507422A patent/JPH10504036A/ja active Pending
- 1995-08-07 AT AT95930118T patent/ATE232727T1/de not_active IP Right Cessation
- 1995-08-07 CA CA002197207A patent/CA2197207C/en not_active Expired - Fee Related
- 1995-08-07 KR KR1019970700855A patent/KR970704441A/ko not_active Application Discontinuation
- 1995-08-07 CZ CZ1997389A patent/CZ292577B6/cs not_active IP Right Cessation
- 1995-08-07 CN CN95195548A patent/CN1101190C/zh not_active Expired - Fee Related
- 1995-08-07 WO PCT/US1995/009956 patent/WO1996004913A1/en active IP Right Grant
- 1995-08-07 PL PL95318506A patent/PL181578B1/pl not_active IP Right Cessation
- 1995-08-07 DK DK95930118T patent/DK0774969T3/da active
- 1995-08-07 ES ES95930118T patent/ES2190456T3/es not_active Expired - Lifetime
- 1995-08-07 DE DE69529678T patent/DE69529678T2/de not_active Expired - Fee Related
- 1995-08-07 MX MX9701121A patent/MX9701121A/es unknown
- 1995-08-07 SK SK181-97A patent/SK18197A3/sk unknown
- 1995-08-07 AU AU33611/95A patent/AU698664B2/en not_active Ceased
- 1995-08-07 EP EP95930118A patent/EP0774969B8/en not_active Expired - Lifetime
-
1997
- 1997-02-10 FI FI970565A patent/FI970565A/fi not_active Application Discontinuation
- 1997-02-11 NO NO19970632A patent/NO314168B1/no unknown
-
2003
- 2003-05-07 CY CY0300040A patent/CY2360B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO970632D0 (no) | 1997-02-11 |
| CZ38997A3 (en) | 1997-11-12 |
| DE69529678T2 (de) | 2003-09-25 |
| ATE232727T1 (de) | 2003-03-15 |
| CA2197207A1 (en) | 1996-02-22 |
| CN1101190C (zh) | 2003-02-12 |
| CZ292577B6 (cs) | 2003-10-15 |
| CN1160350A (zh) | 1997-09-24 |
| IL114808A0 (en) | 1995-12-08 |
| HUT76540A (en) | 1997-09-29 |
| CA2197207C (en) | 2006-10-17 |
| JPH10504036A (ja) | 1998-04-14 |
| PL318506A1 (en) | 1997-06-23 |
| EP0774969A1 (en) | 1997-05-28 |
| AU698664B2 (en) | 1998-11-05 |
| PL181578B1 (pl) | 2001-08-31 |
| DK0774969T3 (da) | 2003-03-31 |
| EP0774969B8 (en) | 2003-07-02 |
| KR970704441A (ko) | 1997-09-06 |
| FI970565A0 (fi) | 1997-02-10 |
| WO1996004913A1 (en) | 1996-02-22 |
| FI970565A (fi) | 1997-02-10 |
| DE69529678D1 (de) | 2003-03-27 |
| SK18197A3 (en) | 1997-09-10 |
| MX9701121A (es) | 1997-05-31 |
| ES2190456T3 (es) | 2003-08-01 |
| CY2360B1 (en) | 2004-06-04 |
| AU3361195A (en) | 1996-03-07 |
| NO970632L (no) | 1997-04-10 |
| EP0774969B1 (en) | 2003-02-19 |
| NO314168B1 (no) | 2003-02-10 |
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| Publication | Publication Date | Title |
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| AU2725392A (en) | Hiv protease inhibitors | |
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| MY109834A (en) | Benzoxazinones as inhibitors of hiv reverse transcriptase | |
| EP0766674A4 (en) | NOVEL HIV PROTEASE INHIBITORS | |
| DZ1766A1 (fr) | Inhibiteurs de vih protéase utiles pour le traitement du sida. | |
| HU9601649D0 (en) | Hiv protease inhibitors | |
| MX9705916A (es) | Terapia de combinacion para infeccion por vih usando el inhibidor de proteasa de vih indinavir y el inhibidor de transcriptasa inversa 3tc, opcionalmente junto con azt, ddi, o ddc. | |
| MX9700036A (es) | Combinacion de compuestos, uso en la preparacion de composiciones para tratar infeccion por el vir s de inmunodeficiencia humana, y composiciones obtenidas. | |
| IL114808A (en) | Combinations of protease inhibitors for the treatment of hiv infection and aids | |
| WO2002096359A3 (en) | Piperazine pentanamide hiv protease inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |