ATE232727T1 - Kombinationen von hiv-protease inhibitoren - Google Patents

Kombinationen von hiv-protease inhibitoren

Info

Publication number
ATE232727T1
ATE232727T1 AT95930118T AT95930118T ATE232727T1 AT E232727 T1 ATE232727 T1 AT E232727T1 AT 95930118 T AT95930118 T AT 95930118T AT 95930118 T AT95930118 T AT 95930118T AT E232727 T1 ATE232727 T1 AT E232727T1
Authority
AT
Austria
Prior art keywords
hiv protease
hiv
protease inhibitors
combinations
treatment
Prior art date
Application number
AT95930118T
Other languages
English (en)
Inventor
Paul J Deutsch
Emilio A Emini
Joseph P Vacca
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE232727T1 publication Critical patent/ATE232727T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT95930118T 1994-08-11 1995-08-07 Kombinationen von hiv-protease inhibitoren ATE232727T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28947494A 1994-08-11 1994-08-11
US33936994A 1994-11-14 1994-11-14
US49246195A 1995-07-20 1995-07-20
PCT/US1995/009956 WO1996004913A1 (en) 1994-08-11 1995-08-07 Hiv protease inhibitor combination

Publications (1)

Publication Number Publication Date
ATE232727T1 true ATE232727T1 (de) 2003-03-15

Family

ID=27403895

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95930118T ATE232727T1 (de) 1994-08-11 1995-08-07 Kombinationen von hiv-protease inhibitoren

Country Status (20)

Country Link
EP (1) EP0774969B8 (de)
JP (1) JPH10504036A (de)
KR (1) KR970704441A (de)
CN (1) CN1101190C (de)
AT (1) ATE232727T1 (de)
AU (1) AU698664B2 (de)
CA (1) CA2197207C (de)
CY (1) CY2360B1 (de)
CZ (1) CZ292577B6 (de)
DE (1) DE69529678T2 (de)
DK (1) DK0774969T3 (de)
ES (1) ES2190456T3 (de)
FI (1) FI970565A (de)
HU (1) HUT76540A (de)
IL (1) IL114808A (de)
MX (1) MX9701121A (de)
NO (1) NO314168B1 (de)
PL (1) PL181578B1 (de)
SK (1) SK18197A3 (de)
WO (1) WO1996004913A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA49803C2 (uk) * 1994-06-03 2002-10-15 Дж.Д. Сьорль Енд Ко Спосіб лікування ретровірусних інфекцій
US6037157A (en) * 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
AU716760B2 (en) * 1996-11-08 2000-03-09 Japan Energy Corporation Aids therapeutic composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US517041A (en) * 1894-03-27 Fruit-picker
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
HU9301446D0 (en) * 1990-11-19 1993-11-29 Monsanto Co Inhibitors or fetrovirus protease
ES2151618T3 (es) * 1990-11-19 2001-01-01 Monsanto Co Inhibidores de proteasas retrovirales.
IE20010533A1 (en) * 1990-11-20 2003-03-05 Abbott Lab Intermediates for preparing retroviral protease inhibiting compounds
DK0541168T3 (da) * 1991-11-08 1998-05-11 Merck & Co Inc HIV-proteaseinhibitorer, som er egnede til behandling af AIDS
DK0727419T3 (da) * 1992-12-29 2002-06-10 Abbott Lab Mellemprodukter til fremstilling af forbindelser, som inhiberer retroviral protease

Also Published As

Publication number Publication date
DK0774969T3 (da) 2003-03-31
PL181578B1 (pl) 2001-08-31
DE69529678D1 (de) 2003-03-27
MX9701121A (es) 1997-05-31
IL114808A (en) 1999-10-28
NO314168B1 (no) 2003-02-10
PL318506A1 (en) 1997-06-23
CZ292577B6 (cs) 2003-10-15
FI970565A0 (fi) 1997-02-10
EP0774969B1 (de) 2003-02-19
EP0774969B8 (de) 2003-07-02
AU698664B2 (en) 1998-11-05
ES2190456T3 (es) 2003-08-01
CZ38997A3 (en) 1997-11-12
JPH10504036A (ja) 1998-04-14
HUT76540A (en) 1997-09-29
CY2360B1 (en) 2004-06-04
CA2197207C (en) 2006-10-17
CA2197207A1 (en) 1996-02-22
FI970565A (fi) 1997-02-10
NO970632D0 (no) 1997-02-11
SK18197A3 (en) 1997-09-10
DE69529678T2 (de) 2003-09-25
KR970704441A (ko) 1997-09-06
WO1996004913A1 (en) 1996-02-22
CN1160350A (zh) 1997-09-24
EP0774969A1 (de) 1997-05-28
NO970632L (no) 1997-04-10
AU3361195A (en) 1996-03-07
CN1101190C (zh) 2003-02-12
IL114808A0 (en) 1995-12-08

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