IL113465A - Pharmaceutical compositions comprising bisphosphonic acids and salts thereof and their preparation - Google Patents

Pharmaceutical compositions comprising bisphosphonic acids and salts thereof and their preparation

Info

Publication number
IL113465A
IL113465A IL11346595A IL11346595A IL113465A IL 113465 A IL113465 A IL 113465A IL 11346595 A IL11346595 A IL 11346595A IL 11346595 A IL11346595 A IL 11346595A IL 113465 A IL113465 A IL 113465A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
salts
bisphosphonic acids
preparation
binder
Prior art date
Application number
IL11346595A
Other languages
English (en)
Other versions
IL113465A0 (en
Original Assignee
Merck & Co Inc U S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22891482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL113465(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc U S filed Critical Merck & Co Inc U S
Publication of IL113465A0 publication Critical patent/IL113465A0/xx
Publication of IL113465A publication Critical patent/IL113465A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL11346595A 1994-04-29 1995-04-24 Pharmaceutical compositions comprising bisphosphonic acids and salts thereof and their preparation IL113465A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23690494A 1994-04-29 1994-04-29

Publications (2)

Publication Number Publication Date
IL113465A0 IL113465A0 (en) 1995-07-31
IL113465A true IL113465A (en) 2005-09-25

Family

ID=22891482

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11346595A IL113465A (en) 1994-04-29 1995-04-24 Pharmaceutical compositions comprising bisphosphonic acids and salts thereof and their preparation

Country Status (33)

Country Link
EP (1) EP0756484B1 (ar)
JP (1) JP3838658B2 (ar)
KR (1) KR100390719B1 (ar)
CN (2) CN1147202A (ar)
AT (1) ATE225661T1 (ar)
AU (1) AU694217C (ar)
BG (1) BG62878B1 (ar)
CA (1) CA2188567C (ar)
CO (1) CO4560546A1 (ar)
CZ (1) CZ291574B6 (ar)
DE (1) DE69528525T2 (ar)
DK (1) DK0756484T3 (ar)
ES (1) ES2183873T3 (ar)
FI (1) FI118206B (ar)
HK (1) HK1009246A1 (ar)
HR (1) HRP950261B1 (ar)
HU (1) HUT76297A (ar)
IL (1) IL113465A (ar)
LV (1) LV13114B (ar)
MX (1) MX9605222A (ar)
MY (1) MY120491A (ar)
NO (1) NO964567D0 (ar)
NZ (1) NZ284719A (ar)
PL (1) PL316987A1 (ar)
PT (1) PT756484E (ar)
RU (1) RU2149003C1 (ar)
SA (1) SA95160013B1 (ar)
SK (1) SK283785B6 (ar)
TW (1) TW390813B (ar)
UA (1) UA44733C2 (ar)
WO (1) WO1995029679A1 (ar)
YU (1) YU49458B (ar)
ZA (1) ZA953437B (ar)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19615812A1 (de) * 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
IL133405A0 (en) * 1997-06-11 2001-04-30 Procter & Gamble Film-coated tablet for improved upper gastrointestinal tract safety
IL121623A (en) * 1997-08-26 2000-06-29 Unipharm Ltd Process for the preparation of solid oral dosage forms comprising alendronic acid
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
EP0998932A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
EP0998933A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Verfahren zur Herstellung von bisphosphonathaltigen pharmazeutischen Zusammensetzungen zur oralen Applikation
BR0010808A (pt) * 1999-05-21 2002-08-27 Novartis Ag Composições farmacêuticas e usos
PL196485B1 (pl) * 2000-05-11 2008-01-31 Inst Farmaceutyczny Stała doustna kompozycja farmaceutyczna zawierająca aminową pochodną kwasu bisfosfonowego i sposób jej wytwarzania
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
KR20120065435A (ko) 2002-05-10 2012-06-20 에프. 호프만-라 로슈 아게 골다공증 치료 및 예방용 비스포스폰산
BR0309691A (pt) 2002-12-20 2005-08-02 Hoffmann La Roche Formulação de ibandronato em alta dose
BRPI0412523A (pt) * 2003-07-11 2006-09-19 Hoffmann La Roche forma de dosagem oral de mesilato de saquinavir
EP1978933A2 (en) * 2005-12-15 2008-10-15 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
GB0616794D0 (en) 2006-08-24 2006-10-04 Arrow Int Ltd Solid dosage form
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
KR102622198B1 (ko) * 2018-03-30 2024-01-09 한미약품 주식회사 빌다글립틴을 함유하는 경구용 고형제제 및 그의 제조 방법
CN112972400A (zh) * 2021-03-09 2021-06-18 华侨大学 可快速崩解的米诺膦酸颗粒及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
US4973576A (en) * 1987-03-10 1990-11-27 Yamanouchi Pharmaceutical Co., Ltd. Bisphophonic acid derivatives and pharmaceutical compositions containing the same
FR2629716B1 (fr) * 1988-04-07 1991-07-19 Sanofi Sa Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique
PH27186A (en) * 1989-09-07 1993-04-16 Ciba Geigy Ag Double-coated granules of disodium pamidronate
FI89366C (fi) * 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
TW237386B (ar) * 1992-04-15 1995-01-01 Ciba Geigy
SE501389C2 (sv) * 1992-04-24 1995-01-30 Leiras Oy Farmaceutiskt preparat och förfarande för dess framställning
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .

Also Published As

Publication number Publication date
HUT76297A (en) 1997-07-28
HU9602986D0 (en) 1997-01-28
PL316987A1 (en) 1997-03-03
ATE225661T1 (de) 2002-10-15
NZ284719A (en) 1998-06-26
DE69528525T2 (de) 2003-11-27
NO964567L (no) 1996-10-28
HRP950261A2 (en) 1997-02-28
PT756484E (pt) 2002-12-31
DE69528525D1 (de) 2002-11-14
MX9605222A (es) 1997-09-30
NO964567D0 (no) 1996-10-28
KR100390719B1 (ko) 2003-10-17
CN1147202A (zh) 1997-04-09
HK1009246A1 (en) 1999-05-28
TW390813B (en) 2000-05-21
YU49458B (sh) 2006-03-03
IL113465A0 (en) 1995-07-31
BG100911A (en) 1997-07-31
FI118206B (fi) 2007-08-31
CO4560546A1 (es) 1998-02-10
UA44733C2 (uk) 2002-03-15
AU2393995A (en) 1995-11-29
CA2188567A1 (en) 1995-11-09
LV13114B (en) 2004-06-20
BG62878B1 (bg) 2000-10-31
MY120491A (en) 2005-11-30
SK139096A3 (en) 1997-05-07
CN1781489A (zh) 2006-06-07
JPH09512551A (ja) 1997-12-16
RU2149003C1 (ru) 2000-05-20
YU27395A (sh) 1998-07-10
EP0756484A1 (en) 1997-02-05
CZ291574B6 (cs) 2003-04-16
DK0756484T3 (da) 2002-11-25
KR970702050A (ko) 1997-05-13
JP3838658B2 (ja) 2006-10-25
CZ315296A3 (en) 1997-04-16
AU694217C (en) 2005-12-15
WO1995029679A1 (en) 1995-11-09
HRP950261B1 (en) 2003-08-31
FI964315A (fi) 1996-10-25
FI964315A0 (fi) 1996-10-25
ZA953437B (en) 1996-01-17
ES2183873T3 (es) 2003-04-01
SK283785B6 (sk) 2004-01-08
SA95160013B1 (ar) 2005-11-23
EP0756484B1 (en) 2002-10-09
CA2188567C (en) 2007-02-20
AU694217B2 (en) 1998-07-16

Similar Documents

Publication Publication Date Title
IL113465A0 (en) Pharmaceutical compositions comprising bisphosphonic acids and salts thereof and their preparation
CA2149052A1 (en) Dry mix formulation for bisphosphonic acids
HUP0204114A2 (hu) Bifoszfonáttartalmú parenterális gyógyászati készítmény
NZ332314A (en) Oral pharmaceutical preparation containing ibandronate or salts thereof in the form of an inner section containing the active ingredient surrounded by a coating free of the active ingredient
HK1072539A1 (en) Use of bisphosphonates in the preparation of a medicament for the treatment of conditings of abnormally increased bone turnover
EP1417975A4 (en) AGENT FOR THE TREATMENT OF DISEASES COMING WITH BONE SCONES WITH EP SB 4 / SB AGONIST AS AN ACTIVE AGENT
CA2221417A1 (en) Anhydrous alendronate monosodium salt formulations
NZ515541A (en) Pharmaceutical compositions comprising bisphosphonates to treat angiogenesis
CA2024694A1 (en) Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
CA2035179A1 (en) Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
CA2200651A1 (en) Sodium alendronate preparation for local administration
EP0341961A3 (en) Polymalonic acids as boneaffinity agents
WO2004058235A3 (en) Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin d derivative
BR9808233A (pt) Preparação farmacêutica
ATE330616T1 (de) Verabreichung von bisphosphonaten durch inhalation zur behandlung von knochenresorption und osteoporosis
IS4392A (is) Pýridýlbisfosfónöt til notkunar sem efni til lækninga
ES2152865A1 (es) Utilizacion de bisfosfonatos en la preparacion de composiciones farmaceuticas para uso intramuscular.
BR0106601A (pt) Composição farmacêutica contendo bisfosfonato para o tratamento de doenças relacionadas ao metabolismo de cálcio e/ou fosfato, seu uso na preparação de medicamento para o tratamento de doenças relacionadas ao metabolismo de cálcio e/ou fosfato, método de tratamento de doenças relacionadas ao metabolismo de cálcio e/ou fosfato
IL141218A0 (en) Alendronic acid, pharmaceutically acceptable salts thereof or mixtures thereof, for use as a medicament or for use in the manufacture of a medicament, pharmaceutical compositions and kits comprising any of thereof, all for inhibiting bone resorption
GEP20002179B (en) Means for Treatment of Herpes

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees