IL112590A - Insulin sensitisers for use in the treatment of renal diseases - Google Patents

Insulin sensitisers for use in the treatment of renal diseases

Info

Publication number
IL112590A
IL112590A IL11259095A IL11259095A IL112590A IL 112590 A IL112590 A IL 112590A IL 11259095 A IL11259095 A IL 11259095A IL 11259095 A IL11259095 A IL 11259095A IL 112590 A IL112590 A IL 112590A
Authority
IL
Israel
Prior art keywords
insulin sensitiser
medicament
formula
pharmaceutically acceptable
insulin
Prior art date
Application number
IL11259095A
Other languages
English (en)
Other versions
IL112590A0 (en
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9402624A external-priority patent/GB9402624D0/en
Priority claimed from GB9410214A external-priority patent/GB9410214D0/en
Priority claimed from GBGB9426019.7A external-priority patent/GB9426019D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL112590A0 publication Critical patent/IL112590A0/xx
Publication of IL112590A publication Critical patent/IL112590A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11259095A 1994-02-10 1995-02-09 Insulin sensitisers for use in the treatment of renal diseases IL112590A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9402624A GB9402624D0 (en) 1994-02-10 1994-02-10 Novel method
GB9410214A GB9410214D0 (en) 1994-05-21 1994-05-21 Novel method
GBGB9426019.7A GB9426019D0 (en) 1994-12-22 1994-12-22 Novel method

Publications (2)

Publication Number Publication Date
IL112590A0 IL112590A0 (en) 1995-06-29
IL112590A true IL112590A (en) 2002-08-14

Family

ID=27267046

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11259095A IL112590A (en) 1994-02-10 1995-02-09 Insulin sensitisers for use in the treatment of renal diseases

Country Status (11)

Country Link
EP (1) EP0777469A1 (es)
JP (1) JPH09512249A (es)
CN (2) CN1083715C (es)
AP (1) AP553A (es)
AU (1) AU700826B2 (es)
CA (1) CA2182986A1 (es)
IL (1) IL112590A (es)
MX (1) MX9603338A (es)
SG (1) SG47100A1 (es)
TW (1) TW475896B (es)
WO (1) WO1995021608A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5885997A (en) * 1996-07-01 1999-03-23 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5985884A (en) * 1996-07-01 1999-11-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6313113B1 (en) 1997-04-15 2001-11-06 Reddy-Cheminor, Inc. Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6011031A (en) * 1997-05-30 2000-01-04 Dr. Reddy's Research Foundation Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
GB9711683D0 (en) * 1997-06-05 1997-08-06 Smithkline Beecham Plc Composition
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
OA11871A (en) 1999-04-23 2006-03-27 Smithkline Beecham Plc Novel pharmaceutical.
BR0013375A (pt) * 1999-08-17 2002-07-23 Smithkline Beecham Plc Composições farmacêuticas contendo derivados tiazolidinodiona e processo para sua preparação
EP1284291A4 (en) * 2000-05-25 2005-06-08 Yamanouchi Pharma Co Ltd PROMOTER OF HUMAN PGC-1
GB0019223D0 (en) * 2000-08-04 2000-09-27 Smithkline Beecham Plc Novel pharmaceutical
JP2008531707A (ja) 2005-03-03 2008-08-14 スミスクライン ビーチャム コーポレーション 医薬品
EP2155769B1 (en) 2007-05-04 2012-06-27 Katholieke Universiteit Leuven KU Leuven Research & Development Tissue degeneration protection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
GB9023584D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
FR2680512B1 (fr) * 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JPH05310719A (ja) * 1992-04-28 1993-11-22 Terumo Corp チアゾリジン−２，４−ジオン誘導体

Also Published As

Publication number Publication date
CN1083715C (zh) 2002-05-01
EP0777469A1 (en) 1997-06-11
CN1318372A (zh) 2001-10-24
WO1995021608A1 (en) 1995-08-17
AP553A (en) 1996-11-06
AP9500717A0 (en) 1995-04-30
SG47100A1 (en) 1998-03-20
JPH09512249A (ja) 1997-12-09
IL112590A0 (en) 1995-06-29
AU1578395A (en) 1995-08-29
CA2182986A1 (en) 1995-08-17
MX9603338A (es) 1997-03-29
TW475896B (en) 2002-02-11
CN1145027A (zh) 1997-03-12
AU700826B2 (en) 1999-01-14

Similar Documents

Publication Publication Date Title
AP553A (en) Use of insulin sensitizers for treating renal failure.
KR100697582B1 (ko) 케톤증 개선제
RU2190425C2 (ru) Способ и композиция для лечения и предупреждения гиперурикемии
EP0695183B1 (en) Use of thiazolidinediones for the treatment of atherosclerosis and eating disorders
NO314065B1 (no) Farmasöytisk sammensetning omfattende en insulinsensitivitetsenhancer og etbiguanid ved behandling av diabetes
EP0921798A1 (en) Novel treatment of leptine resistance
US20010044458A1 (en) Use of insulin sensitisers for treating renal diseases
US20020115699A1 (en) Method for treating renal disease
WO2000076488A2 (en) Use of a ppar agonist for treating type 1 diabetes
US20040266833A1 (en) Novel use of certain insulin sensitizers or ppar-gamma agonists
NZ506200A (en) Use of a leptine sensitiser in combination with leptin to treat leptine resistance conditions (e.g. obesity)
CZ7799A3 (cs) Farmaceutický prostředek proti leptinové rezistenci
AU7217000A (en) Novel treatment of leptin resistance
CZ32998A3 (cs) Výroba léčiva pro snížení množství exogenního insulinu
HU224436B1 (hu) Az 5-[4-{2-[N-metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxotiazolidin alkalmazása vesebetegségek kezelésére szolgáló gyógyszerkészítmények előállítására
BG107384A (bg) ИЗПОЛЗВАНЕ НА PPARгама АГОНИСТ ЗА ПОЛУЧАВАНЕ НА МЕДИКАМЕНТ ЗА ЛЕЧЕНИЕ И ПРОФИЛАКТИКА НА СЪСТОЯНИЯ СВЪРЗАНИ СЪС СЪРДЕЧНА ИНСУЛИНОВА РЕЗИСТЕНТНОСТ
ZA200300283B (en) Treatment and prevention of cardiac insulin resistance associated conditions.
CZ198798A3 (cs) Způsob glykace proteinu, jeho použití a farmaceutický přípravek s jeho obsahem
AU2000254153A1 (en) Treatment and prevention of cardiac insulin resistance associated conditions
AU6662400A (en) Use of thiazolidinediones for the treatment of atherosclerosis and eating disorders
CZ20024067A3 (cs) Léčivo pro léčení nebo profylaxi srdeční rezistence na insulin

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees