IL112403A - A method for producing mature growth hormone from cattle at the end of which amine alanine in E.COLI - Google Patents

A method for producing mature growth hormone from cattle at the end of which amine alanine in E.COLI

Info

Publication number
IL112403A
IL112403A IL11240386A IL11240386A IL112403A IL 112403 A IL112403 A IL 112403A IL 11240386 A IL11240386 A IL 11240386A IL 11240386 A IL11240386 A IL 11240386A IL 112403 A IL112403 A IL 112403A
Authority
IL
Israel
Prior art keywords
bgh
dna
coli
growth hormone
sequence
Prior art date
Application number
IL11240386A
Other languages
English (en)
Hebrew (he)
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/704,362 external-priority patent/US4861868A/en
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of IL112403A publication Critical patent/IL112403A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/168Steroids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/184Hormones
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/10Feeding-stuffs specially adapted for particular animals for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Birds (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL11240386A 1985-02-22 1986-02-21 A method for producing mature growth hormone from cattle at the end of which amine alanine in E.COLI IL112403A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/704,362 US4861868A (en) 1985-02-22 1985-02-22 Production of proteins in procaryotes
US06/824,202 US5037806A (en) 1985-02-22 1986-02-04 Biologically active method using somatotropins
IL7795086A IL77950A (en) 1985-02-22 1986-02-21 Method and preparations for increasing milk production in cattle

Publications (1)

Publication Number Publication Date
IL112403A true IL112403A (en) 2001-10-31

Family

ID=27107310

Family Applications (4)

Application Number Title Priority Date Filing Date
IL7795086A IL77950A (en) 1985-02-22 1986-02-21 Method and preparations for increasing milk production in cattle
IL11240386A IL112403A (en) 1985-02-22 1986-02-21 A method for producing mature growth hormone from cattle at the end of which amine alanine in E.COLI
IL11240286A IL112402A (en) 1985-02-22 1986-02-21 Methods for producing N-alanyl porcine somatotropin and compositions thereof
IL11240395A IL112403A0 (en) 1985-02-22 1995-01-20 Method for producing a heterologous polypeptide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL7795086A IL77950A (en) 1985-02-22 1986-02-21 Method and preparations for increasing milk production in cattle

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11240286A IL112402A (en) 1985-02-22 1986-02-21 Methods for producing N-alanyl porcine somatotropin and compositions thereof
IL11240395A IL112403A0 (en) 1985-02-22 1995-01-20 Method for producing a heterologous polypeptide

Country Status (22)

Country Link
US (1) US5037806A (ja)
EP (1) EP0193515B1 (ja)
JP (3) JP2583214B2 (ja)
KR (1) KR920000849B1 (ja)
CN (3) CN1021973C (ja)
AT (1) ATE141327T1 (ja)
AU (2) AU596575B2 (ja)
CA (1) CA1338981C (ja)
DE (1) DE3650553T2 (ja)
DK (1) DK80886A (ja)
ES (1) ES8801851A1 (ja)
GR (1) GR860509B (ja)
HU (1) HU210671B (ja)
IE (1) IE80663B1 (ja)
IL (4) IL77950A (ja)
LT (1) LT3916B (ja)
MX (1) MX9203728A (ja)
NO (1) NO300551B1 (ja)
NZ (1) NZ215260A (ja)
PT (1) PT82070B (ja)
RO (1) RO106956B1 (ja)
RU (2) RU2072393C1 (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101981B1 (en) 1980-08-26 2006-09-05 Regents Of The University Of California Bovine growth hormone recombinantly produced in E. coli
US6692941B1 (en) 1980-08-26 2004-02-17 The Regents Of The University Of California Bovine growth hormone
US4861868A (en) * 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
US5141922A (en) * 1985-02-22 1992-08-25 Monsanto Company Biologically active proteins and a method for their use
US6916914B1 (en) * 1985-06-26 2005-07-12 Pharmacia & Upjohn Co. Purification of somatotropin from transformed microorganisms
AU599922B2 (en) * 1985-09-10 1990-08-02 Natinco Nv Improving carcass quality
IE67890B1 (en) 1986-03-27 1996-05-01 Monsanto Co Enhanced Protein production in bacteria by employing a novel ribosome binding site
GB8701848D0 (en) * 1987-01-28 1987-03-04 Celltech Ltd Polypeptides
US5104806A (en) * 1987-03-12 1992-04-14 Amgen, Inc. Porcine growth hormone analogs encoding dna
US5244882A (en) * 1987-03-12 1993-09-14 Amgen, Inc. Porcine growth hormone analogs, and compositions
US4863736A (en) 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
AU3058489A (en) * 1988-02-17 1989-09-06 Upjohn Company, The Methods for controlling norleucine content in polypeptides
US5130422A (en) * 1988-08-29 1992-07-14 Monsanto Company Variant somatotropin-encoding DNA
US5089473A (en) * 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
US5663305A (en) * 1989-07-10 1997-09-02 The Upjohn Company Somatotropin analogs
EP0482124B1 (en) * 1989-07-10 1993-12-22 The Upjohn Company Somatotropin analogs
DE3930522A1 (de) * 1989-09-13 1991-03-21 Bayer Ag Rekombinante aprotinin-varianten - gentechnisches verfahren zur mikrobiellen herstellung von homogen prozessierten aprotinin-varianten sowie die therapeutische anwendung derselben
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US6583115B1 (en) 1989-10-12 2003-06-24 Ohio University/Edison Biotechnology Institute Methods for treating acromegaly and giantism with growth hormone antagonists
US6787336B1 (en) 1989-10-12 2004-09-07 Ohio University/Edison Biotechnology Institute DNA encoding growth hormone antagonists
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5951972A (en) * 1990-05-04 1999-09-14 American Cyanamid Company Stabilization of somatotropins and other proteins by modification of cysteine residues
US5767080A (en) * 1996-05-01 1998-06-16 Cargill, Incorporated Enhanced milk production in dairy cattle
GB9803424D0 (en) * 1998-02-18 1998-04-15 Pfizer Ltd Performance enhancement
KR20010080015A (ko) 1998-10-05 2001-08-22 다케다 야쿠힌 고교 가부시키가이샤 N-말단 메티오닌의 제거방법
US6890731B1 (en) * 2000-03-27 2005-05-10 Applera Corporation Isolated human G-protein coupled receptors that are members of the aminergic subfamily, nucleic acid molecules encoding human GPCR proteins, and uses thereof
CN101665788B (zh) * 2009-09-21 2011-11-09 山西大学 人工合成猪生长激素基因及其表达纯化方法
CN101907626A (zh) * 2010-07-20 2010-12-08 广东省农业科学院兽医研究所 一种猪饲料中猪源蛋白的检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
IL59690A (en) 1980-03-24 1983-11-30 Yeda Res & Dev Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
JPS58996A (ja) * 1981-06-01 1983-01-06 ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− 細菌中での牛成長ホルモン遺伝子のクロ−ン化
US4436824A (en) * 1981-06-09 1984-03-13 Ortho Diagnostic Systems, Inc. Leukocyte migration through antigen containing agaroses for immunocompetence testing
EP0085036A1 (en) * 1982-01-18 1983-08-03 Monsanto Company Method for improved bovine milk production
EP0095361B1 (en) 1982-05-25 1989-07-26 Eli Lilly And Company Cloning vectors for expression of exogenous protein
EP0103395A3 (en) * 1982-08-17 1985-05-22 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
AU2092983A (en) * 1982-11-08 1984-05-17 Genentech Inc. Porcine growth hormone produced by recombinant dna technology
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
US4661454A (en) * 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
CA1340597C (en) * 1984-08-27 1999-06-22 Haim Aviv Expression vectors containing pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods
HU196714B (en) * 1984-10-04 1989-01-30 Monsanto Co Process for producing non-aqueous composition comprising somatotropin
US4861868A (en) * 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes

Also Published As

Publication number Publication date
RU2072393C1 (ru) 1997-01-27
EP0193515B1 (en) 1996-08-14
PT82070A (en) 1986-03-01
IE860467L (en) 1986-08-22
DK80886D0 (da) 1986-02-21
IL112403A0 (en) 1995-03-30
CN1021973C (zh) 1993-09-01
IL112402A (en) 1997-02-18
ES8801851A1 (es) 1988-02-16
JP2634390B2 (ja) 1997-07-23
ATE141327T1 (de) 1996-08-15
EP0193515A3 (en) 1990-05-30
IL112402A0 (en) 1995-03-30
LT3916B (en) 1996-04-25
RO106956B1 (ro) 1993-08-30
CN86101830A (zh) 1986-09-03
NO300551B1 (no) 1997-06-16
DE3650553T2 (de) 1997-02-27
DE3650553D1 (de) 1996-09-19
US5037806A (en) 1991-08-06
KR920000849B1 (ko) 1992-01-30
AU4282589A (en) 1990-02-08
KR870008028A (ko) 1987-09-23
JP2863113B2 (ja) 1999-03-03
HU210671B (en) 1995-06-28
JPH07309890A (ja) 1995-11-28
CN1051302A (zh) 1991-05-15
GR860509B (en) 1986-06-18
JP2583214B2 (ja) 1997-02-19
DK80886A (da) 1986-11-21
CA1338981C (en) 1997-03-11
AU596575B2 (en) 1990-05-10
JPH07304687A (ja) 1995-11-21
EP0193515A2 (en) 1986-09-03
NZ215260A (en) 1989-01-06
MX9203728A (es) 1992-09-01
CN1100272A (zh) 1995-03-22
ES552234A0 (es) 1988-02-16
IE80663B1 (en) 1998-11-18
LTIP1819A (en) 1995-08-25
AU632293B2 (en) 1992-12-24
PT82070B (pt) 1988-01-22
RU2094439C1 (ru) 1997-10-27
IL77950A (en) 1996-09-12
HUT40701A (en) 1987-01-28
NO860658L (no) 1986-08-25
AU5385486A (en) 1986-08-28
JPS61233629A (ja) 1986-10-17

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