IL110581A0 - Insulin formulation - Google Patents
Insulin formulationInfo
- Publication number
- IL110581A0 IL110581A0 IL11058194A IL11058194A IL110581A0 IL 110581 A0 IL110581 A0 IL 110581A0 IL 11058194 A IL11058194 A IL 11058194A IL 11058194 A IL11058194 A IL 11058194A IL 110581 A0 IL110581 A0 IL 110581A0
- Authority
- IL
- Israel
- Prior art keywords
- insulin
- formulation
- zinc
- total
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/106,106 US5534488A (en) | 1993-08-13 | 1993-08-13 | Insulin formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
IL110581A0 true IL110581A0 (en) | 1994-11-11 |
Family
ID=22309529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11058194A IL110581A0 (en) | 1993-08-13 | 1994-08-08 | Insulin formulation |
Country Status (27)
Country | Link |
---|---|
US (1) | US5534488A (ko) |
EP (1) | EP0646379B1 (ko) |
JP (1) | JPH07149660A (ko) |
KR (1) | KR950005324A (ko) |
CN (1) | CN1109364A (ko) |
AT (1) | ATE207761T1 (ko) |
AU (1) | AU674975B2 (ko) |
BR (1) | BR9403204A (ko) |
CA (1) | CA2129763A1 (ko) |
CO (1) | CO4230235A1 (ko) |
CZ (1) | CZ193794A3 (ko) |
DE (1) | DE69428860T2 (ko) |
DK (1) | DK0646379T3 (ko) |
ES (1) | ES2164691T3 (ko) |
HU (1) | HUT67853A (ko) |
IL (1) | IL110581A0 (ko) |
NO (1) | NO942959L (ko) |
NZ (1) | NZ264197A (ko) |
PE (1) | PE14495A1 (ko) |
PH (1) | PH30757A (ko) |
PL (1) | PL177002B1 (ko) |
PT (1) | PT646379E (ko) |
RU (1) | RU2135205C1 (ko) |
TW (1) | TW326394B (ko) |
UA (1) | UA27874C2 (ko) |
YU (1) | YU50494A (ko) |
ZA (1) | ZA945939B (ko) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5578238A (en) * | 1992-10-30 | 1996-11-26 | Lord Corporation | Magnetorheological materials utilizing surface-modified particles |
AR002976A1 (es) * | 1995-03-31 | 1998-05-27 | Lilly Co Eli | Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas |
EP1396272A1 (en) * | 1997-12-23 | 2004-03-10 | Eli Lilly & Company | Insoluble Insulin Compositions for Controlling Blood Glucose |
CO4970787A1 (es) * | 1997-12-23 | 2000-11-07 | Lilly Co Eli | Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea |
US6956021B1 (en) * | 1998-08-25 | 2005-10-18 | Advanced Inhalation Research, Inc. | Stable spray-dried protein formulations |
WO2001000675A1 (en) * | 1999-06-29 | 2001-01-04 | Eli Lilly And Company | Protamine-free insoluble acylated insulin compositions |
US7678364B2 (en) | 1999-08-25 | 2010-03-16 | Alkermes, Inc. | Particles for inhalation having sustained release properties |
EP1265630B1 (en) * | 2000-03-24 | 2006-06-07 | Genentech, Inc. | Use of insulin for the treatment of cartilagenous disorders |
WO2002029833A1 (en) * | 2000-10-06 | 2002-04-11 | The Adviser - Defence Research & Development Organisation | A magneto sensitive fluid composition and a process for preparation thereof |
US6875368B2 (en) * | 2000-11-29 | 2005-04-05 | The Adviser Defence Research And Development Organisation, Ministry Of Defence, Government Of India | Magnetorheological fluid composition and a process for preparation thereof |
HUP0500733A3 (en) * | 2001-02-09 | 2010-01-28 | Genentech Inc | Crystallization of igf-1 |
DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
ES2664189T3 (es) | 2002-01-09 | 2018-04-18 | Emisphere Technologies, Inc. | Polimorfos de 4-(4-cloro-2-hidroxibenzoil)aminobutanoato de sodio |
DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
US7658721B2 (en) * | 2004-01-16 | 2010-02-09 | Biodel Inc. | Sublingual drug delivery device |
US20080248999A1 (en) * | 2007-04-04 | 2008-10-09 | Biodel Inc. | Amylin formulations |
US20080085298A1 (en) * | 2004-03-12 | 2008-04-10 | Biodel, Inc. | Rapid Mucosal Gel or Film Insulin Compositions |
DK2319500T3 (da) * | 2004-03-12 | 2013-02-04 | Biodel Inc | Hurtigtvirkende sammensætninger til afgivelse af lægemiddel |
US20080096800A1 (en) * | 2004-03-12 | 2008-04-24 | Biodel, Inc. | Rapid mucosal gel or film insulin compositions |
US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
ES2729825T3 (es) | 2004-05-06 | 2019-11-06 | Emisphere Tech Inc | Formas poliméricas cristalinas de N-[8-(2-hidroxibenzoil)amino]caprilato monosódico |
NZ551241A (en) * | 2004-05-14 | 2010-08-27 | Emisphere Tech Inc | Aryl ketone compounds and compositions for delivering active agents |
CN103223160B (zh) * | 2004-07-19 | 2015-02-18 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
WO2006017541A2 (en) * | 2004-08-03 | 2006-02-16 | Emisphere Technologies, Inc. | Antidiabetic oral insulin-biguanide combination |
US20060078622A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
US7713929B2 (en) * | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
US8084420B2 (en) * | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
AU2007238114B2 (en) * | 2006-04-12 | 2010-10-14 | Biodel, Inc. | Rapid acting and long acting insulin combination formulations |
EP3050568B1 (en) | 2007-03-13 | 2020-12-02 | JDS Therapeutics, LLC | Methods and compositions for the sustained release of chromium |
WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
PT2203181T (pt) | 2007-10-16 | 2018-05-10 | Biocon Ltd | Uma composição farmacêutica sólida para administração por via oral e o seu processo de fabrico |
AU2009204309B2 (en) * | 2008-01-04 | 2012-11-22 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
DK2349324T3 (en) | 2008-10-17 | 2017-12-11 | Sanofi Aventis Deutschland | COMBINATION OF AN INSULIN AND A GLP-1 AGONIST |
US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
PT2498802E (pt) | 2009-11-13 | 2015-04-13 | Sanofi Aventis Deutschland | Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina |
PE20121316A1 (es) | 2009-11-13 | 2012-10-05 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende un agonista de glp-1 y metionina |
CN102770153B (zh) * | 2010-02-22 | 2014-05-07 | 卡斯西部储备大学 | 呈可溶和结晶形式的长效胰岛素类似物制剂 |
HUE031181T2 (en) | 2010-08-30 | 2017-06-28 | Sanofi Aventis Deutschland | Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes |
MX344925B (es) | 2011-03-01 | 2017-01-11 | N21 Acquisition Holding Llc | Composiciones de insulina y cromo para el tratamiento y prevención de diabetes, hipoglucemia y alteraciones relacionadas. |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
FI3229828T3 (fi) | 2014-12-12 | 2023-05-29 | Sanofi Aventis Deutschland | Glargiini-insuliinin/liksisenatidin vakiosuhteinen formulaatio |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
EP3413900A1 (en) | 2016-02-11 | 2018-12-19 | Nutrition 21, LLC | Chromium containing compositions for improving health and fitness |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2626228A (en) * | 1945-05-17 | 1953-01-20 | Novo Terapeutisk Labor As | Method of producing crystalline insulin |
US2882202A (en) * | 1950-04-05 | 1959-04-14 | Novo Terapeutisk Labor As | Insulin crystal preparations and methods of producing them |
US2882203A (en) * | 1951-06-26 | 1959-04-14 | Novo Terapeutisk Labor As | Injectable insulin preparation with protracted effect |
US2849370A (en) * | 1953-06-04 | 1958-08-26 | Novo Terapeutisk Labortorium A | Injectable insulin preparations with protracted effect and process of producing same |
US3102077A (en) * | 1953-08-19 | 1963-08-27 | Christensen Henry Marinus | Preparation of insulin containing 2.75 to 8 percent zinc content |
US2819999A (en) * | 1953-11-13 | 1958-01-14 | Novo Terapeutisk Labor As | Process for crystallization of insulin using freeze dried insulin as seeding material |
US2799622A (en) * | 1953-11-14 | 1957-07-16 | Novo Terapeutisk Labor As | Process of producing insulin crystals of substantially uniform size and compositions thereof |
US3060093A (en) * | 1957-07-18 | 1962-10-23 | Nordisk Insulinlab | Slowly acting insulin preparation in crystalline form and method of preparation |
DE2933946A1 (de) * | 1979-08-22 | 1981-03-12 | Hoechst Ag, 6000 Frankfurt | Insulinkristallsuspension und verfahren zu ihrer herstellung. |
FI78616C (fi) * | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
PH23446A (en) * | 1986-10-20 | 1989-08-07 | Novo Industri As | Peptide preparations |
DE3827533A1 (de) * | 1988-08-13 | 1990-02-15 | Hoechst Ag | Pharmazeutische zubereitung zur behandlung des diabetes mellitus |
-
1993
- 1993-08-13 US US08/106,106 patent/US5534488A/en not_active Expired - Fee Related
-
1994
- 1994-08-04 HU HU9402287A patent/HUT67853A/hu unknown
- 1994-08-08 ZA ZA945939A patent/ZA945939B/xx unknown
- 1994-08-08 NZ NZ264197A patent/NZ264197A/en unknown
- 1994-08-08 IL IL11058194A patent/IL110581A0/xx not_active IP Right Cessation
- 1994-08-08 BR BR9403204A patent/BR9403204A/pt not_active Application Discontinuation
- 1994-08-08 PE PE1994248043A patent/PE14495A1/es not_active Application Discontinuation
- 1994-08-09 PH PH48764A patent/PH30757A/en unknown
- 1994-08-09 EP EP94305883A patent/EP0646379B1/en not_active Expired - Lifetime
- 1994-08-09 NO NO942959A patent/NO942959L/no not_active Application Discontinuation
- 1994-08-09 CA CA002129763A patent/CA2129763A1/en not_active Abandoned
- 1994-08-09 TW TW083107259A patent/TW326394B/zh active
- 1994-08-09 AT AT94305883T patent/ATE207761T1/de not_active IP Right Cessation
- 1994-08-09 DK DK94305883T patent/DK0646379T3/da active
- 1994-08-09 RU RU94028671A patent/RU2135205C1/ru active
- 1994-08-09 PT PT94305883T patent/PT646379E/pt unknown
- 1994-08-09 ES ES94305883T patent/ES2164691T3/es not_active Expired - Lifetime
- 1994-08-09 DE DE69428860T patent/DE69428860T2/de not_active Expired - Fee Related
- 1994-08-09 KR KR1019940019550A patent/KR950005324A/ko active IP Right Grant
- 1994-08-09 PL PL94304600A patent/PL177002B1/pl unknown
- 1994-08-09 UA UA94085696A patent/UA27874C2/uk unknown
- 1994-08-09 CO CO94035010A patent/CO4230235A1/es unknown
- 1994-08-10 YU YU50494A patent/YU50494A/sh unknown
- 1994-08-10 CZ CZ941937A patent/CZ193794A3/cs unknown
- 1994-08-10 JP JP6188204A patent/JPH07149660A/ja not_active Withdrawn
- 1994-08-10 CN CN94109082A patent/CN1109364A/zh active Pending
- 1994-08-12 AU AU70247/94A patent/AU674975B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
HU9402287D0 (en) | 1994-09-28 |
NO942959L (no) | 1995-02-14 |
AU7024794A (en) | 1995-02-23 |
PL304600A1 (en) | 1995-02-20 |
ZA945939B (en) | 1996-02-08 |
UA27874C2 (uk) | 2000-10-16 |
ES2164691T3 (es) | 2002-03-01 |
DK0646379T3 (da) | 2001-12-03 |
EP0646379A1 (en) | 1995-04-05 |
RU2135205C1 (ru) | 1999-08-27 |
DE69428860D1 (de) | 2001-12-06 |
CZ193794A3 (en) | 1995-03-15 |
TW326394B (en) | 1998-02-11 |
YU50494A (sh) | 1997-01-08 |
BR9403204A (pt) | 1995-04-18 |
ATE207761T1 (de) | 2001-11-15 |
AU674975B2 (en) | 1997-01-16 |
CO4230235A1 (es) | 1995-10-19 |
PT646379E (pt) | 2002-03-28 |
NO942959D0 (no) | 1994-08-09 |
DE69428860T2 (de) | 2002-05-02 |
HUT67853A (en) | 1995-05-29 |
PL177002B1 (pl) | 1999-09-30 |
PE14495A1 (es) | 1995-06-02 |
CN1109364A (zh) | 1995-10-04 |
KR950005324A (ko) | 1995-03-20 |
NZ264197A (en) | 1997-01-29 |
US5534488A (en) | 1996-07-09 |
JPH07149660A (ja) | 1995-06-13 |
CA2129763A1 (en) | 1995-02-14 |
EP0646379B1 (en) | 2001-10-31 |
PH30757A (en) | 1997-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |