IL109255A - Process for the preparation of 6-fluoro-2-haloquinolines and their use in the preparation of antimicrobial 1,8-benzo(b) naphthyridine derivatives - Google Patents
Process for the preparation of 6-fluoro-2-haloquinolines and their use in the preparation of antimicrobial 1,8-benzo(b) naphthyridine derivativesInfo
- Publication number
- IL109255A IL109255A IL10925594A IL10925594A IL109255A IL 109255 A IL109255 A IL 109255A IL 10925594 A IL10925594 A IL 10925594A IL 10925594 A IL10925594 A IL 10925594A IL 109255 A IL109255 A IL 109255A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- fluoro
- pct
- hal
- hydrogen atom
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000005054 naphthyridines Chemical class 0.000 title 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9304163A FR2703681B1 (fr) | 1993-04-08 | 1993-04-08 | Procede de preparation de fluoro-6-halogeno-2 quinoleine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL109255A0 IL109255A0 (en) | 1994-07-31 |
| IL109255A true IL109255A (en) | 2000-01-31 |
Family
ID=9445879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10925594A IL109255A (en) | 1993-04-08 | 1994-04-07 | Process for the preparation of 6-fluoro-2-haloquinolines and their use in the preparation of antimicrobial 1,8-benzo(b) naphthyridine derivatives |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5624933A (cs) |
| EP (1) | EP0693060B1 (cs) |
| JP (1) | JP3666753B2 (cs) |
| KR (1) | KR100330141B1 (cs) |
| AT (1) | ATE164155T1 (cs) |
| AU (1) | AU680493B2 (cs) |
| CA (1) | CA2158746C (cs) |
| CZ (1) | CZ283705B6 (cs) |
| DE (1) | DE69409101T2 (cs) |
| DK (1) | DK0693060T3 (cs) |
| ES (1) | ES2114189T3 (cs) |
| FI (1) | FI113263B (cs) |
| FR (1) | FR2703681B1 (cs) |
| GR (1) | GR3026401T3 (cs) |
| HU (1) | HU221861B1 (cs) |
| IL (1) | IL109255A (cs) |
| NO (1) | NO305752B1 (cs) |
| NZ (1) | NZ265072A (cs) |
| SK (1) | SK281139B6 (cs) |
| TW (1) | TW261612B (cs) |
| WO (1) | WO1994024113A1 (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7510170B2 (en) | 2006-11-09 | 2009-03-31 | Guan Hong Enterprise Co., Ltd. | Humidifying fan |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1458205A (en) * | 1973-04-13 | 1976-12-08 | Pfizer | Fused pyrimidin-4- 3h-ones as antiallergy agents |
| US4190659A (en) * | 1973-08-27 | 1980-02-26 | Sandoz, Inc. | Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters |
| US4710507A (en) * | 1983-12-22 | 1987-12-01 | Pfizer Inc. | Quinolone inotropic agents |
| DK111387A (da) * | 1986-03-05 | 1987-09-06 | Otsuka Pharma Co Ltd | Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne |
| DE3713672A1 (de) * | 1987-04-24 | 1988-11-17 | Bayer Ag | Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren |
| NZ232092A (en) * | 1989-01-16 | 1992-05-26 | Bellon Labor Sa Roger | 8-halo-7-fluoro-4-oxo-1,4-dihydro-benzo(b)(1,8) naphthyridine-3-carboxylic acid esters and preparation thereof |
| NZ232090A (en) * | 1989-01-16 | 1990-12-21 | Bellon Labor Sa Roger | Halogen-containing 1-substituted-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof |
| NZ232091A (en) * | 1989-01-16 | 1990-12-21 | Bellon Labor Sa Roger | 7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof |
| US4948894A (en) * | 1989-02-21 | 1990-08-14 | American Cyanamid Company | 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids |
| RO108347B1 (ro) * | 1989-10-30 | 1994-04-28 | Bellon Labor Sa Roger | DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA |
| FR2682384B1 (fr) * | 1991-10-10 | 1995-04-07 | Bellon Laboratoires | Procede de preparation de benzo (b) naphtyridines. |
| FR2682378B1 (fr) * | 1991-10-10 | 1995-04-07 | Bellon Laboratoires | Nouveaux derives de l'acide fluoroquinoleine carboxylique-3 et leur preparation. |
-
1993
- 1993-04-08 FR FR9304163A patent/FR2703681B1/fr not_active Expired - Fee Related
-
1994
- 1994-04-07 IL IL10925594A patent/IL109255A/xx active IP Right Grant
- 1994-04-07 AU AU65408/94A patent/AU680493B2/en not_active Ceased
- 1994-04-07 CA CA002158746A patent/CA2158746C/fr not_active Expired - Fee Related
- 1994-04-07 DK DK94913146T patent/DK0693060T3/da active
- 1994-04-07 ES ES94913146T patent/ES2114189T3/es not_active Expired - Lifetime
- 1994-04-07 TW TW083103037A patent/TW261612B/zh active
- 1994-04-07 DE DE69409101T patent/DE69409101T2/de not_active Expired - Fee Related
- 1994-04-07 EP EP94913146A patent/EP0693060B1/fr not_active Expired - Lifetime
- 1994-04-07 HU HU9502934A patent/HU221861B1/hu not_active IP Right Cessation
- 1994-04-07 SK SK1256-95A patent/SK281139B6/sk unknown
- 1994-04-07 CZ CZ952600A patent/CZ283705B6/cs not_active IP Right Cessation
- 1994-04-07 JP JP52281694A patent/JP3666753B2/ja not_active Expired - Fee Related
- 1994-04-07 AT AT94913146T patent/ATE164155T1/de not_active IP Right Cessation
- 1994-04-07 NZ NZ265072A patent/NZ265072A/xx unknown
- 1994-04-07 KR KR1019950704416A patent/KR100330141B1/ko not_active Expired - Fee Related
- 1994-04-07 WO PCT/FR1994/000391 patent/WO1994024113A1/fr active IP Right Grant
- 1994-10-20 US US08/448,404 patent/US5624933A/en not_active Expired - Fee Related
-
1995
- 1995-10-02 NO NO953914A patent/NO305752B1/no unknown
- 1995-10-05 FI FI954750A patent/FI113263B/fi not_active IP Right Cessation
-
1998
- 1998-03-19 GR GR970402800T patent/GR3026401T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |