BG102081A - New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application - Google Patents

New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application

Info

Publication number
BG102081A
BG102081A BG102081A BG10208197A BG102081A BG 102081 A BG102081 A BG 102081A BG 102081 A BG102081 A BG 102081A BG 10208197 A BG10208197 A BG 10208197A BG 102081 A BG102081 A BG 102081A
Authority
BG
Bulgaria
Prior art keywords
preparation
azabicyclo
heptane
application
new derivatives
Prior art date
Application number
BG102081A
Other languages
Bulgarian (bg)
Other versions
BG63084B1 (en
Inventor
Denis Largeau
Patrick Leon
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9506353A external-priority patent/FR2734822B1/en
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of BG102081A publication Critical patent/BG102081A/en
Publication of BG63084B1 publication Critical patent/BG63084B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

The derivatives are used for the preparation of adenosineagonists. They have the general formulawhere R is a hydrogen atom or optionally radical with the formulawhere R1 is alkyl radical containing from 1 to 4 carbon atoms, andAr is phenyl radical or optionally a substituted - or - naphtylradical.18 claims
BG102081A 1995-05-30 1997-11-28 New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application BG63084B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9506353A FR2734822B1 (en) 1995-05-30 1995-05-30 NEW 2-AZABICYCLO (2.2.1) HEPTANE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION
PCT/FR1996/000793 WO1996038447A1 (en) 1995-05-30 1996-05-28 2-azabicyclo[2.2.1]heptane derivatives, preparation and application thereof

Publications (2)

Publication Number Publication Date
BG102081A true BG102081A (en) 1998-11-30
BG63084B1 BG63084B1 (en) 2001-03-30

Family

ID=9479463

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102081A BG63084B1 (en) 1995-05-30 1997-11-28 New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application

Country Status (25)

Country Link
EP (1) EP0828740B1 (en)
JP (2) JP4097287B2 (en)
KR (1) KR100488393B1 (en)
CN (1) CN1249034C (en)
AP (1) AP973A (en)
AT (1) ATE205210T1 (en)
AU (1) AU711057B2 (en)
BG (1) BG63084B1 (en)
BR (1) BR9608513A (en)
CA (1) CA2219456A1 (en)
CZ (1) CZ286483B6 (en)
DE (1) DE69615020T2 (en)
DK (1) DK0828740T3 (en)
EA (1) EA000963B1 (en)
ES (1) ES2163023T3 (en)
GR (1) GR3036536T3 (en)
HU (1) HUP9900787A3 (en)
NO (1) NO311431B1 (en)
OA (1) OA10543A (en)
PL (1) PL186195B1 (en)
PT (1) PT828740E (en)
RO (1) RO119414B1 (en)
SI (1) SI0828740T1 (en)
SK (1) SK283809B6 (en)
UA (1) UA64695C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0719719A (en) * 1993-07-05 1995-01-20 Matsushita Electric Ind Co Ltd Heat insulation box

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4803272A (en) * 1987-02-24 1989-02-07 E. I. Du Pont De Nemours And Company S-modified adenosyl-1,8-diamino-3-thiooctane derivatives
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
JP4097287B2 (en) 2008-06-11
UA64695C2 (en) 2004-03-15
AP973A (en) 2001-06-08
HUP9900787A2 (en) 1999-07-28
PT828740E (en) 2002-02-28
HUP9900787A3 (en) 2001-05-28
CN1249034C (en) 2006-04-05
CZ286483B6 (en) 2000-04-12
EP0828740B1 (en) 2001-09-05
CN1397549A (en) 2003-02-19
ES2163023T3 (en) 2002-01-16
KR100488393B1 (en) 2005-08-30
NO975487L (en) 1997-11-28
MX9708995A (en) 1998-03-31
SK283809B6 (en) 2004-02-03
BR9608513A (en) 1999-02-02
CA2219456A1 (en) 1996-12-05
KR19990022103A (en) 1999-03-25
AP9701149A0 (en) 1998-01-31
DK0828740T3 (en) 2002-12-02
RO119414B1 (en) 2004-10-29
DE69615020D1 (en) 2001-10-11
PL186195B1 (en) 2003-11-28
OA10543A (en) 2002-05-31
NO975487D0 (en) 1997-11-28
EA199700440A1 (en) 1998-08-27
PL323680A1 (en) 1998-04-14
BG63084B1 (en) 2001-03-30
SI0828740T1 (en) 2001-12-31
NO311431B1 (en) 2001-11-26
GR3036536T3 (en) 2001-12-31
AU711057B2 (en) 1999-10-07
CZ377797A3 (en) 1998-03-18
SK161297A3 (en) 1998-04-08
EA000963B1 (en) 2000-08-28
AU6008796A (en) 1996-12-18
EP0828740A1 (en) 1998-03-18
DE69615020T2 (en) 2002-03-21
JPH11505861A (en) 1999-05-25
JP2007262089A (en) 2007-10-11
ATE205210T1 (en) 2001-09-15

Similar Documents

Publication Publication Date Title
AU5165393A (en) Substituted benzylaminoquinuclidines as substance p antagonists
GR3023938T3 (en) 3',5'-ditertbutyl-4'-hydroxyflavones, method for their preparation and pharmaceutical compositions with an antioxidant and antivasoconstricting activity
ES8505518A1 (en) Amino-acids derivatives, process for their preparation and their use.
ES8101550A1 (en) Pyrrolidine-2-methanol derivatives, process for their preparation and medicaments containing them.
AU576199B2 (en) Beta-carboline derivatives
ZA831226B (en) Novel derivatives of psoralen
AU667904B2 (en) Antitumoral compounds
BG102081A (en) New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application
AU2030397A (en) Use of n-aryl-2-hydroxyalkylamides for stimulating or inducing hair growth and/or arresting hair loss
GR3005131T3 (en)
AU2845489A (en) Process for preparing hydroxyakylating agents, the agents so obtained, and their use
AU2307595A (en) A process for the preparation of 5,6-dihydroxy-2-amino- 1,2,3,4-tetrahydronaphthalene derivatives
TW328083B (en) New derivatives of β-methoxy acrylic acid, their preparation process and their use as pesticides
CA2152919A1 (en) Prodrugs of Antiinflammatory 3-Acyl-2-Oxindole-1-Carboxamides
ATE18993T1 (en) DIBENZOCYCLOHEPTENYLIDE COMPOUNDS FOR USE IN MODULATION OF IMMUNE RESPONSE.
JO1676B1 (en) Further indenoindoles compounds ii
MX9804255A (en) Dithiazoldioxides and the use thereof as microbicides.
ES8702909A1 (en) Tetrahydro-beta-carboline derivatives and process for the preparation thereof.
EP0195668A3 (en) Carbacyclin derivatives
TW358809B (en) Phenylamidinothiophene compound and anti-inflammatory agent containing the same
ES8602825A1 (en) Pesticidal phosphorodithioic compounds.
MX9605415A (en) Propiophenone derivative and processes for preparing the same.