DE69409101D1 - Verfahren zur herstellung von 6-fluoro-2-halogeno-chinolin - Google Patents

Verfahren zur herstellung von 6-fluoro-2-halogeno-chinolin

Info

Publication number
DE69409101D1
DE69409101D1 DE69409101T DE69409101T DE69409101D1 DE 69409101 D1 DE69409101 D1 DE 69409101D1 DE 69409101 T DE69409101 T DE 69409101T DE 69409101 T DE69409101 T DE 69409101T DE 69409101 D1 DE69409101 D1 DE 69409101D1
Authority
DE
Germany
Prior art keywords
pct
fluoro
hal
hydrogen atom
quinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69409101T
Other languages
English (en)
Other versions
DE69409101T2 (de
Inventor
Herve Garcia
Roland Jacquot
Patrick Leon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of DE69409101D1 publication Critical patent/DE69409101D1/de
Application granted granted Critical
Publication of DE69409101T2 publication Critical patent/DE69409101T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69409101T 1993-04-08 1994-04-07 Verfahren zur herstellung von 6-fluoro-2-halogeno-chinolin Expired - Fee Related DE69409101T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9304163A FR2703681B1 (fr) 1993-04-08 1993-04-08 Procede de preparation de fluoro-6-halogeno-2 quinoleine
PCT/FR1994/000391 WO1994024113A1 (fr) 1993-04-08 1994-04-07 Procede de preparation de fluoro-6 halogeno-2 quinoleine

Publications (2)

Publication Number Publication Date
DE69409101D1 true DE69409101D1 (de) 1998-04-23
DE69409101T2 DE69409101T2 (de) 1998-07-23

Family

ID=9445879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409101T Expired - Fee Related DE69409101T2 (de) 1993-04-08 1994-04-07 Verfahren zur herstellung von 6-fluoro-2-halogeno-chinolin

Country Status (21)

Country Link
US (1) US5624933A (de)
EP (1) EP0693060B1 (de)
JP (1) JP3666753B2 (de)
KR (1) KR100330141B1 (de)
AT (1) ATE164155T1 (de)
AU (1) AU680493B2 (de)
CA (1) CA2158746C (de)
CZ (1) CZ283705B6 (de)
DE (1) DE69409101T2 (de)
DK (1) DK0693060T3 (de)
ES (1) ES2114189T3 (de)
FI (1) FI113263B (de)
FR (1) FR2703681B1 (de)
GR (1) GR3026401T3 (de)
HU (1) HU221861B1 (de)
IL (1) IL109255A (de)
NO (1) NO305752B1 (de)
NZ (1) NZ265072A (de)
SK (1) SK281139B6 (de)
TW (1) TW261612B (de)
WO (1) WO1994024113A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7510170B2 (en) 2006-11-09 2009-03-31 Guan Hong Enterprise Co., Ltd. Humidifying fan

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1458205A (en) * 1973-04-13 1976-12-08 Pfizer Fused pyrimidin-4- 3h-ones as antiallergy agents
US4190659A (en) * 1973-08-27 1980-02-26 Sandoz, Inc. Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4710507A (en) * 1983-12-22 1987-12-01 Pfizer Inc. Quinolone inotropic agents
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
NZ232090A (en) * 1989-01-16 1990-12-21 Bellon Labor Sa Roger Halogen-containing 1-substituted-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof
NZ232091A (en) * 1989-01-16 1990-12-21 Bellon Labor Sa Roger 7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof
NZ232092A (en) * 1989-01-16 1992-05-26 Bellon Labor Sa Roger 8-halo-7-fluoro-4-oxo-1,4-dihydro-benzo(b)(1,8) naphthyridine-3-carboxylic acid esters and preparation thereof
US4948894A (en) * 1989-02-21 1990-08-14 American Cyanamid Company 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
FR2682384B1 (fr) * 1991-10-10 1995-04-07 Bellon Laboratoires Procede de preparation de benzo (b) naphtyridines.
FR2682378B1 (fr) * 1991-10-10 1995-04-07 Bellon Laboratoires Nouveaux derives de l'acide fluoroquinoleine carboxylique-3 et leur preparation.

Also Published As

Publication number Publication date
ATE164155T1 (de) 1998-04-15
NO305752B1 (no) 1999-07-19
US5624933A (en) 1997-04-29
FR2703681B1 (fr) 1995-05-12
HUT73560A (en) 1996-08-28
EP0693060A1 (de) 1996-01-24
SK281139B6 (sk) 2000-12-11
AU6540894A (en) 1994-11-08
GR3026401T3 (en) 1998-06-30
CZ283705B6 (cs) 1998-06-17
TW261612B (de) 1995-11-01
FI954750A (fi) 1995-10-05
HU221861B1 (hu) 2003-02-28
CA2158746A1 (fr) 1994-10-27
JP3666753B2 (ja) 2005-06-29
JPH08508747A (ja) 1996-09-17
AU680493B2 (en) 1997-07-31
FI113263B (fi) 2004-03-31
KR960701854A (ko) 1996-03-28
NO953914L (no) 1995-10-02
KR100330141B1 (ko) 2002-09-27
SK125695A3 (en) 1996-06-05
DK0693060T3 (da) 1998-10-19
IL109255A0 (en) 1994-07-31
EP0693060B1 (de) 1998-03-18
CZ260095A3 (en) 1996-01-17
CA2158746C (fr) 2006-08-29
FR2703681A1 (fr) 1994-10-14
WO1994024113A1 (fr) 1994-10-27
IL109255A (en) 2000-01-31
NO953914D0 (no) 1995-10-02
FI954750A0 (fi) 1995-10-05
NZ265072A (en) 1997-08-22
ES2114189T3 (es) 1998-05-16
HU9502934D0 (en) 1995-12-28
DE69409101T2 (de) 1998-07-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY, FR

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8339 Ceased/non-payment of the annual fee