GB1458205A - Fused pyrimidin-4- 3h-ones as antiallergy agents - Google Patents
Fused pyrimidin-4- 3h-ones as antiallergy agentsInfo
- Publication number
- GB1458205A GB1458205A GB5590073A GB5590073A GB1458205A GB 1458205 A GB1458205 A GB 1458205A GB 5590073 A GB5590073 A GB 5590073A GB 5590073 A GB5590073 A GB 5590073A GB 1458205 A GB1458205 A GB 1458205A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ones
- alkoxy
- alkyl
- antiallergy agents
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Abstract
1458205 Pharmaceutical compositions PFIZER Inc 3 Dec 1973 [13 April 1973] 55900/73 Heading A5B [Also in Division C2] Compounds I, II, III, IV and their cationic salts in which R is OH, alkoxy, NH 2 or NHOH, R 1 is H, alkyl or phenyl and each of R 2 , R 3 , R 4 and R 5 is H, halogen, alkyl or alkoxy and in addition R 2 and R 3 or R 3 and R 4 may be methylenedioxy or ethylenedioxy have anti-allergy properties and from with a carrier a pharmaceutical composition which may be administered orally, parenterally or by inhalation. The composition may also contain theophylline or sympathomimetic amines. Ethyl 7, 8-dimethoxy- 4 - oxo - 3H pyrimido[4, 5 -6 ]- quinoline-2-carboxylate causes hypertension and bradycardia in dogs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35102573A | 1973-04-13 | 1973-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1458205A true GB1458205A (en) | 1976-12-08 |
Family
ID=23379271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5590073A Expired GB1458205A (en) | 1973-04-13 | 1973-12-03 | Fused pyrimidin-4- 3h-ones as antiallergy agents |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5018481A (en) |
| AR (3) | AR205556A1 (en) |
| AT (1) | AT342596B (en) |
| BE (1) | BE813571A (en) |
| BG (1) | BG25988A3 (en) |
| CA (1) | CA1027945A (en) |
| CH (1) | CH619950A5 (en) |
| DD (1) | DD111207A5 (en) |
| DE (1) | DE2418498A1 (en) |
| DK (1) | DK142621B (en) |
| ES (1) | ES425238A1 (en) |
| FI (1) | FI55658C (en) |
| FR (1) | FR2225166B1 (en) |
| GB (1) | GB1458205A (en) |
| HU (1) | HU171157B (en) |
| IE (1) | IE41673B1 (en) |
| IL (1) | IL44569A (en) |
| LU (1) | LU69855A1 (en) |
| NL (1) | NL170285C (en) |
| NO (1) | NO139735C (en) |
| RO (1) | RO64918A (en) |
| YU (1) | YU36960B (en) |
| ZA (1) | ZA742351B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4011324A (en) * | 1976-01-20 | 1977-03-08 | Pfizer Inc. | Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents |
| DE2757915A1 (en) * | 1976-12-28 | 1978-07-06 | Mitsubishi Yuka Pharma | PYRIMIDOCHINOXALINE DERIVATIVES, METHOD FOR MANUFACTURING THE SAME AND MEDICINAL PRODUCTS FOR THE TREATMENT OF ALLERGIC ASTHMA |
| JPS59210071A (en) * | 1982-12-30 | 1984-11-28 | バイオメジヤ−・インコ−ポレ−テツド | Antiviral compound |
| DE68908786T2 (en) * | 1988-06-16 | 1994-03-17 | Smith Kline French Lab | Condensed pyrimidine derivatives, processes and intermediates for their preparation and pharmaceutical preparations containing them. |
| FR2682378B1 (en) * | 1991-10-10 | 1995-04-07 | Bellon Laboratoires | NOVEL DERIVATIVES OF FLUOROQUINOLEINE ACID CARBOXYLIC-3 AND THEIR PREPARATION. |
| FR2703681B1 (en) * | 1993-04-08 | 1995-05-12 | Bellon Labor Sa Roger | PROCESS FOR PREPARING FLUORO-6-HALOGENO-2 QUINOLEINE |
| US7482455B2 (en) * | 2002-10-16 | 2009-01-27 | Smithkline Beecham Corporation | Chemical compounds |
| CN114502665A (en) * | 2019-09-30 | 2022-05-13 | 富士胶片株式会社 | Colored resin particle dispersion, ink set, ink jet printing method, method for producing oil-soluble dye, and printed matter |
-
1973
- 1973-12-03 GB GB5590073A patent/GB1458205A/en not_active Expired
-
1974
- 1974-01-01 AR AR257178A patent/AR205556A1/en active
- 1974-01-01 AR AR257177A patent/AR207459A1/en active
- 1974-01-01 AR AR253237A patent/AR205342A1/en active
- 1974-04-04 NO NO741231A patent/NO139735C/en unknown
- 1974-04-04 IL IL44569A patent/IL44569A/en unknown
- 1974-04-10 DK DK200974AA patent/DK142621B/en not_active IP Right Cessation
- 1974-04-10 YU YU1016/74A patent/YU36960B/en unknown
- 1974-04-10 ES ES425238A patent/ES425238A1/en not_active Expired
- 1974-04-10 NL NLAANVRAGE7404894,A patent/NL170285C/en not_active IP Right Cessation
- 1974-04-10 FI FI1095/74A patent/FI55658C/en active
- 1974-04-11 DD DD177859A patent/DD111207A5/xx unknown
- 1974-04-11 BE BE1005874A patent/BE813571A/en not_active IP Right Cessation
- 1974-04-11 DE DE2418498A patent/DE2418498A1/en not_active Ceased
- 1974-04-11 CA CA197,461A patent/CA1027945A/en not_active Expired
- 1974-04-11 IE IE781/74A patent/IE41673B1/en unknown
- 1974-04-11 CH CH511074A patent/CH619950A5/en not_active IP Right Cessation
- 1974-04-11 ZA ZA00742351A patent/ZA742351B/en unknown
- 1974-04-12 HU HU74PI00000413A patent/HU171157B/en unknown
- 1974-04-12 FR FR7413092A patent/FR2225166B1/fr not_active Expired
- 1974-04-12 LU LU69855A patent/LU69855A1/xx unknown
- 1974-04-13 JP JP49041582A patent/JPS5018481A/ja active Pending
- 1974-04-13 BG BG7426410A patent/BG25988A3/xx unknown
- 1974-04-13 RO RO7478412A patent/RO64918A/en unknown
- 1974-04-16 AT AT315174A patent/AT342596B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1027945A (en) | 1978-03-14 |
| DE2418498A1 (en) | 1974-11-07 |
| DK142621C (en) | 1981-08-03 |
| HU171157B (en) | 1977-11-28 |
| NL170285C (en) | 1982-10-18 |
| LU69855A1 (en) | 1974-11-21 |
| DD111207A5 (en) | 1975-02-05 |
| ATA315174A (en) | 1977-08-15 |
| AU6750074A (en) | 1975-10-09 |
| AR205556A1 (en) | 1976-05-14 |
| DK142621B (en) | 1980-12-01 |
| FI55658C (en) | 1979-09-10 |
| YU101674A (en) | 1982-06-18 |
| AT342596B (en) | 1978-04-10 |
| BG25988A3 (en) | 1979-01-12 |
| NL170285B (en) | 1982-05-17 |
| RO64918A (en) | 1980-01-15 |
| NO139735C (en) | 1979-05-02 |
| NL7404894A (en) | 1974-10-15 |
| CH619950A5 (en) | 1980-10-31 |
| IE41673L (en) | 1974-10-13 |
| FR2225166A1 (en) | 1974-11-08 |
| JPS5018481A (en) | 1975-02-26 |
| BE813571A (en) | 1974-10-11 |
| IL44569A0 (en) | 1974-06-30 |
| IE41673B1 (en) | 1980-02-27 |
| NO741231L (en) | 1974-10-15 |
| AR205342A1 (en) | 1976-04-30 |
| YU36960B (en) | 1984-08-31 |
| AR207459A1 (en) | 1976-10-08 |
| FR2225166B1 (en) | 1977-06-03 |
| IL44569A (en) | 1979-05-31 |
| ZA742351B (en) | 1975-04-30 |
| ES425238A1 (en) | 1976-05-16 |
| FI55658B (en) | 1979-05-31 |
| NO139735B (en) | 1979-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5671073A (en) | Imidazole derivative | |
| MY102087A (en) | Phenethanolamine derivatives. | |
| ES8406080A1 (en) | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same. | |
| EP0092391A3 (en) | Novel piperidine derivatives and pharmaceutical compositions containing same | |
| GB1268894A (en) | Substituted cinnamamides and compositions containing them | |
| GB1458205A (en) | Fused pyrimidin-4- 3h-ones as antiallergy agents | |
| ES8502099A1 (en) | Derivatives of dihydrodibenzocycloheptylidene-ethylamine. | |
| GB1432809A (en) | Coumarin derivatives | |
| GB1369249A (en) | Amines the preparation thereof and their use in pharmaceutical compositions | |
| GB1439724A (en) | Berbine derivatives and pharmaceutical compositions containing them | |
| GB1174051A (en) | Aminophenol Derivatives and Analgesic and Antipyretic Compositions | |
| GB1180794A (en) | Novel Arylhydrazino-Imidazolines and Preparation Thereof | |
| IE39546B1 (en) | Quinazoline-derived amines | |
| GB1289240A (en) | ||
| GB1397731A (en) | Monothiachromone-2-carboxylic acids | |
| IE40893L (en) | PYRIMIDO [1,2-a] QUINOLINES | |
| GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
| ES8400099A1 (en) | Diazolyl alkanoles, process for their preparation and their use as antimycotic agents. | |
| ES405479A1 (en) | Benzodiazepin-2-ones | |
| GB1453863A (en) | Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity | |
| ES8503356A1 (en) | Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same. | |
| GB1181295A (en) | Improvements in or relating to Naphthalene Derivatives and the Manufacture Thereof | |
| IE39658B1 (en) | N-substituted glycinates, a process for their preparation and pharmaceutical compositions containing them | |
| GB1244481A (en) | Benzothiazine derivatives and the preparation thereof | |
| US3498987A (en) | 9,9-dimethyl-10-amino-alkylacridans |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |