IL109128A - Phosphonomethyl dipeptides and pharmaceutical preparations containing them - Google Patents

Phosphonomethyl dipeptides and pharmaceutical preparations containing them

Info

Publication number
IL109128A
IL109128A IL10912894A IL10912894A IL109128A IL 109128 A IL109128 A IL 109128A IL 10912894 A IL10912894 A IL 10912894A IL 10912894 A IL10912894 A IL 10912894A IL 109128 A IL109128 A IL 109128A
Authority
IL
Israel
Prior art keywords
compound
leucyl
alkyl
tryptophan
hydrogen
Prior art date
Application number
IL10912894A
Other languages
English (en)
Hebrew (he)
Other versions
IL109128A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL109128A0 publication Critical patent/IL109128A0/xx
Publication of IL109128A publication Critical patent/IL109128A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)
IL10912894A 1993-03-30 1994-03-25 Phosphonomethyl dipeptides and pharmaceutical preparations containing them IL109128A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93400824A EP0618224A1 (en) 1993-03-30 1993-03-30 Phosphonomethyldipeptides

Publications (2)

Publication Number Publication Date
IL109128A0 IL109128A0 (en) 1994-06-24
IL109128A true IL109128A (en) 1999-09-22

Family

ID=8214693

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10912894A IL109128A (en) 1993-03-30 1994-03-25 Phosphonomethyl dipeptides and pharmaceutical preparations containing them

Country Status (20)

Country Link
EP (2) EP0618224A1 (el)
JP (1) JP3541230B2 (el)
KR (1) KR100311852B1 (el)
CN (1) CN1120844A (el)
AT (1) ATE192456T1 (el)
AU (1) AU670866B2 (el)
CA (1) CA2156742C (el)
DE (1) DE69424281T2 (el)
DK (1) DK0691985T3 (el)
ES (1) ES2148322T3 (el)
FI (1) FI954656A (el)
GR (1) GR3034015T3 (el)
HU (1) HU217836B (el)
IL (1) IL109128A (el)
NO (1) NO953877L (el)
NZ (1) NZ262996A (el)
PT (1) PT691985E (el)
TW (1) TW290550B (el)
WO (1) WO1994022908A1 (el)
ZA (1) ZA942091B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583123A (en) * 1994-12-22 1996-12-10 Ciba-Geigy Corporation Certain tetrazole derivatives
US5550119A (en) * 1995-03-02 1996-08-27 Ciba-Geigy Corporation Phosphono substituted tetrazole derivatives as ECE inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726714D0 (en) * 1987-11-14 1987-12-16 Beecham Group Plc Compounds
JP2811608B2 (ja) * 1991-04-26 1998-10-15 日本ケミファ株式会社 ホスホン酸アミド誘導体およびエンドセリン変換酵素阻害剤
JPH05105698A (ja) * 1991-06-13 1993-04-27 Takeda Chem Ind Ltd ホスホン酸誘導体、その製造法および用途

Also Published As

Publication number Publication date
NZ262996A (en) 1996-06-25
PT691985E (pt) 2000-08-31
DE69424281T2 (de) 2000-09-21
KR100311852B1 (ko) 2002-02-28
DK0691985T3 (da) 2000-08-07
TW290550B (el) 1996-11-11
JP3541230B2 (ja) 2004-07-07
HU217836B (hu) 2000-04-28
CA2156742A1 (en) 1994-10-13
AU670866B2 (en) 1996-08-01
IL109128A0 (en) 1994-06-24
AU6298994A (en) 1994-10-24
NO953877L (no) 1995-11-30
FI954656A0 (fi) 1995-09-29
WO1994022908A1 (en) 1994-10-13
ATE192456T1 (de) 2000-05-15
DE69424281D1 (en) 2000-06-08
CN1120844A (zh) 1996-04-17
EP0691985B1 (en) 2000-05-03
EP0618224A1 (en) 1994-10-05
NO953877D0 (no) 1995-09-29
ZA942091B (en) 1994-10-24
GR3034015T3 (en) 2000-11-30
CA2156742C (en) 2001-04-17
EP0691985A1 (en) 1996-01-17
HUT72465A (en) 1996-04-29
JPH08508480A (ja) 1996-09-10
ES2148322T3 (es) 2000-10-16
KR960701088A (ko) 1996-02-24
HU9502852D0 (en) 1995-11-28
FI954656A (fi) 1995-09-29

Similar Documents

Publication Publication Date Title
US4346078A (en) Novel anticoagulant agmatine derivatives and process for the preparation thereof
EP0640617B1 (en) Substituted azepino (2,1-a)isoquinoline compounds
US5169841A (en) Renin inhibitors
JPH09504525A (ja) ビスホスホン酸塩類と成長ホルモン分泌促進薬との併用剤
AU715305B2 (en) Thrombin inhibitors
EP0595878A1 (en) Acylmercaptoalkanoyldipeptides, methods of preparation and their therapeutic use
KR100354654B1 (ko) 피리미디논 화합물, 이를 함유하는 약제학적 조성물 및이의 제조 방법.
NO317640B1 (no) Nye fosfonsyresubstituerte benzazepinon-N-edikksyrederivater, fremgangsmate for deres fremstilling, og legemidler inneholdende slike
US5587375A (en) Azepinone compounds useful in the inhibition of ACE and NEP
EP0500989B1 (en) N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents
EP0691985B1 (en) Phosphonomethyldipeptides
US5608078A (en) Phosphonomethyldipeptides and process for preparation thereof
EP1200432B1 (en) Amido spiropiperidines promote the release of growth hormone
HU203770B (en) Process for producing histidine derivatives and pharmaceutical compositions containing them as active components
US4400511A (en) 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids
US4456594A (en) N-Carboxyalkylproline-containing tripeptides
HU203771B (en) Process for producing renine-inhibiting dipeptide-carbamoyl-derivatives and pharmaceutical compositions containing them as active components
HU204070B (en) Process for producing dipeptide derivatvies having renin inhibiting effect and pharmaceutical compositions comprising same
US4386075A (en) Renally active tetrapeptides
WO2000012539A1 (fr) Composes de peptides
MXPA01006708A (en) Thrombin inhibitors
JPH05310695A (ja) 芳香族化合物
JPH0328418B2 (el)

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void