IL108633A - History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them - Google Patents

History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them

Info

Publication number
IL108633A
IL108633A IL10863394A IL10863394A IL108633A IL 108633 A IL108633 A IL 108633A IL 10863394 A IL10863394 A IL 10863394A IL 10863394 A IL10863394 A IL 10863394A IL 108633 A IL108633 A IL 108633A
Authority
IL
Israel
Prior art keywords
phenyl
compound
dioxide
ethyl
tetrahydro
Prior art date
Application number
IL10863394A
Other languages
English (en)
Hebrew (he)
Other versions
IL108633A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939303013A external-priority patent/GB9303013D0/en
Priority claimed from GB939315155A external-priority patent/GB9315155D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL108633A0 publication Critical patent/IL108633A0/xx
Publication of IL108633A publication Critical patent/IL108633A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL10863394A 1993-02-15 1994-02-14 History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them IL108633A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939303013A GB9303013D0 (en) 1993-02-15 1993-02-15 Hypolipidaemic compounds
GB939315155A GB9315155D0 (en) 1993-07-22 1993-07-22 Hypolipidaemic compounds

Publications (2)

Publication Number Publication Date
IL108633A0 IL108633A0 (en) 1994-05-30
IL108633A true IL108633A (en) 1998-07-15

Family

ID=26302465

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10863394A IL108633A (en) 1993-02-15 1994-02-14 History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them

Country Status (16)

Country Link
US (1) US5723458A (de)
EP (1) EP0683774B1 (de)
JP (1) JP2886341B2 (de)
AT (1) ATE225778T1 (de)
AU (1) AU6008894A (de)
CA (1) CA2156183A1 (de)
DE (1) DE69431517T2 (de)
DK (1) DK0683774T3 (de)
ES (1) ES2184758T3 (de)
HK (1) HK1003939A1 (de)
HU (1) HUT71610A (de)
IL (1) IL108633A (de)
PT (1) PT683774E (de)
TW (1) TW275064B (de)
WO (1) WO1994018184A1 (de)
ZA (1) ZA941003B (de)

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US5994391A (en) * 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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EP1354604A1 (de) * 1998-12-23 2003-10-22 G.D. Searle LLC. Kombinationen für kardiovaskuläre Indikationen
AU776953B2 (en) * 1998-12-23 2004-09-30 G.D. Searle Llc Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications
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US5276025A (en) * 1992-09-09 1994-01-04 Merck & Co., Inc. Heterobicyclic sulfonamides

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TW275064B (de) 1996-05-01
HUT71610A (en) 1996-01-29
DE69431517D1 (de) 2002-11-14
ATE225778T1 (de) 2002-10-15
JPH08506576A (ja) 1996-07-16
IL108633A0 (en) 1994-05-30
DK0683774T3 (da) 2003-02-10
JP2886341B2 (ja) 1999-04-26
HK1003939A1 (en) 1998-11-13
PT683774E (pt) 2003-02-28
AU6008894A (en) 1994-08-29
HU9501818D0 (en) 1995-08-28
DE69431517T2 (de) 2003-06-12
US5723458A (en) 1998-03-03
ES2184758T3 (es) 2003-04-16
WO1994018184A1 (en) 1994-08-18
EP0683774A1 (de) 1995-11-29
EP0683774B1 (de) 2002-10-09
ZA941003B (en) 1995-08-14
CA2156183A1 (en) 1994-08-18

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