IL108119A0 - Purine derivatives their preparation and pharmaceutical compositions containing them - Google Patents

Purine derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL108119A0
IL108119A0 IL10811993A IL10811993A IL108119A0 IL 108119 A0 IL108119 A0 IL 108119A0 IL 10811993 A IL10811993 A IL 10811993A IL 10811993 A IL10811993 A IL 10811993A IL 108119 A0 IL108119 A0 IL 108119A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
purine derivatives
purine
Prior art date
Application number
IL10811993A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL108119A0 publication Critical patent/IL108119A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL10811993A 1992-12-23 1993-12-21 Purine derivatives their preparation and pharmaceutical compositions containing them IL108119A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK921552A DK155292D0 (da) 1992-12-23 1992-12-23 Kemiske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
IL108119A0 true IL108119A0 (en) 1994-04-12

Family

ID=8105999

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10811993A IL108119A0 (en) 1992-12-23 1993-12-21 Purine derivatives their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US5484774A (xx)
EP (1) EP0675896A1 (xx)
JP (1) JPH08504777A (xx)
KR (1) KR960700260A (xx)
AU (1) AU690532B2 (xx)
BG (1) BG61607B1 (xx)
CA (1) CA2152341A1 (xx)
CZ (1) CZ164295A3 (xx)
DK (1) DK155292D0 (xx)
FI (1) FI953127A (xx)
HU (1) HUT72409A (xx)
IL (1) IL108119A0 (xx)
NO (1) NO952508L (xx)
NZ (1) NZ259323A (xx)
PL (1) PL175029B1 (xx)
SK (1) SK82695A3 (xx)
WO (1) WO1994014832A1 (xx)
ZA (1) ZA939663B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683989A (en) * 1993-12-17 1997-11-04 Novo Nordisk A/S Treatment of ischemias by administration of 2,N6 -substituted adenosines
AU2603197A (en) 1996-04-10 1997-10-29 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Use of an a1 adenosine receptor agonist to treat cerebral ischaemia
GB9610031D0 (en) * 1996-05-14 1996-07-17 Glaxo Group Ltd Chemical compounds
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
GB9913932D0 (en) 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
JP2001163854A (ja) * 1999-09-28 2001-06-19 Nippon Nohyaku Co Ltd チオアルキルアミン誘導体及びその製造方法
US7342003B2 (en) * 2001-10-25 2008-03-11 King Pharmaceuticals Research And Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
JP4956802B2 (ja) * 2003-09-10 2012-06-20 独立行政法人理化学研究所 非天然型塩基を有するヌクレオシド又はヌクレオチド及びその利用
WO2005033121A2 (en) * 2003-10-03 2005-04-14 King Pharmaceuticals Research & Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
CN101041638B (zh) * 2007-04-29 2010-05-26 浙江工业大学 含咪唑硫醚结构的手性胺及其制备方法与应用
CN101041637B (zh) * 2007-04-29 2010-06-09 浙江工业大学 含咪唑硫醚结构的手性胺质子酸盐及其制备方法与应用
CN105273026B (zh) * 2014-07-22 2018-11-06 上海医药工业研究院 一种药物中间体及其制备方法和应用
CN105273025B (zh) * 2014-07-22 2019-07-26 上海医药工业研究院 一种制备坎格雷洛的中间体及其制备方法和应用
CN105273027B (zh) * 2014-07-22 2018-11-06 上海医药工业研究院 坎格雷洛中间体及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788958A (fr) * 1971-09-18 1973-03-19 Schering Ag Derives d'adenosine et leur procede de preparation
ATE50777T1 (de) * 1984-04-18 1990-03-15 Whitby Research Inc Cardio-vasodilatatore n-6-substituierte adenosine.
CA2028002A1 (en) * 1989-10-19 1991-04-20 Daniel P. Becker Method of treating gastrointestinal motility disorders
US5055569A (en) * 1989-10-19 1991-10-08 G. D. Searle & Co. N-(6)-substituted adenosine compounds
AU654507B2 (en) * 1990-09-25 1994-11-10 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
HUT61567A (en) * 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
DK62692D0 (xx) * 1992-05-14 1992-05-14 Novo Nordisk As
WO1994002497A1 (en) * 1992-07-15 1994-02-03 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Sulfo-derivatives of adenosine

Also Published As

Publication number Publication date
PL175029B1 (pl) 1998-10-30
FI953127A (fi) 1995-08-21
BG61607B1 (bg) 1998-01-30
FI953127A0 (fi) 1995-06-22
AU5809394A (en) 1994-07-19
NO952508L (no) 1995-08-22
WO1994014832A1 (en) 1994-07-07
ZA939663B (en) 1995-06-23
BG99741A (bg) 1996-04-30
KR960700260A (ko) 1996-01-19
NZ259323A (en) 1996-06-25
AU690532B2 (en) 1998-04-30
CA2152341A1 (en) 1994-07-07
JPH08504777A (ja) 1996-05-21
CZ164295A3 (en) 1996-01-17
EP0675896A1 (en) 1995-10-11
NO952508D0 (no) 1995-06-22
SK82695A3 (en) 1996-04-03
US5484774A (en) 1996-01-16
DK155292D0 (da) 1992-12-23
PL309610A1 (en) 1995-10-30
HUT72409A (en) 1996-04-29
HU9501856D0 (en) 1995-08-28

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