IL106217A - Pharmaceutical compositions containing organic nitrites for vasodilator therapy - Google Patents
Pharmaceutical compositions containing organic nitrites for vasodilator therapyInfo
- Publication number
- IL106217A IL106217A IL106217A IL10621793A IL106217A IL 106217 A IL106217 A IL 106217A IL 106217 A IL106217 A IL 106217A IL 10621793 A IL10621793 A IL 10621793A IL 106217 A IL106217 A IL 106217A
- Authority
- IL
- Israel
- Prior art keywords
- nitrite
- dosage form
- nitrites
- composition
- organic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/908,224 US5278192A (en) | 1992-07-02 | 1992-07-02 | Method of vasodilator therapy for treating a patient with a condition |
Publications (2)
Publication Number | Publication Date |
---|---|
IL106217A0 IL106217A0 (en) | 1993-11-15 |
IL106217A true IL106217A (en) | 1998-04-05 |
Family
ID=25425396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL106217A IL106217A (en) | 1992-07-02 | 1993-07-02 | Pharmaceutical compositions containing organic nitrites for vasodilator therapy |
Country Status (19)
Country | Link |
---|---|
US (2) | US5278192A (no) |
EP (1) | EP0604642A1 (no) |
JP (1) | JP2729333B2 (no) |
KR (1) | KR0170789B1 (no) |
CN (1) | CN1086997A (no) |
AU (1) | AU667948B2 (no) |
CA (1) | CA2116785C (no) |
CZ (1) | CZ39894A3 (no) |
HU (1) | HUT70501A (no) |
IL (1) | IL106217A (no) |
MX (1) | MX9303982A (no) |
NO (1) | NO305886B1 (no) |
NZ (1) | NZ254490A (no) |
OA (1) | OA09890A (no) |
PL (1) | PL302613A1 (no) |
SK (1) | SK23594A3 (no) |
TW (1) | TW261530B (no) |
WO (1) | WO1994001103A1 (no) |
ZA (1) | ZA934771B (no) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5278192A (en) * | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
US5646181A (en) * | 1992-07-02 | 1997-07-08 | Research Foundation Of State University Of New York | Method and compositions for treating impotence |
GB9301192D0 (en) | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
US5973011A (en) * | 1994-03-30 | 1999-10-26 | Isis Pharma Gmbh | Pharmaceutical preparations and medicaments for the prevention and treatment of endothelial dysfunction |
US5681278A (en) * | 1994-06-23 | 1997-10-28 | Cormedics Corp. | Coronary vasculature treatment method |
US5594032A (en) * | 1994-11-10 | 1997-01-14 | Gonzalez-Cadavid; Nestor F. | Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA |
US5665077A (en) * | 1995-04-24 | 1997-09-09 | Nitrosci Pharmaceuticals Llc | Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis |
US5645839A (en) * | 1995-06-07 | 1997-07-08 | Trustees Of Boston University | Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis |
US5658936A (en) * | 1995-09-18 | 1997-08-19 | Brigham & Women's Hospital, Inc. | Enhancement of erectile function with renin-angiotensin system inhibitors |
US6387407B1 (en) | 1995-09-29 | 2002-05-14 | L.A.M. Pharmaceutical Corporation | Topical drug preparations |
US6251436B1 (en) | 1995-09-29 | 2001-06-26 | L.A.M. Pharmaceutical Corporation | Drug preparations for treating sexual dysfunction |
US5897880A (en) | 1995-09-29 | 1999-04-27 | Lam Pharmaceuticals, Llc. | Topical drug preparations |
US6036977A (en) * | 1995-09-29 | 2000-03-14 | L.A.M. Pharmaceutical Corp. | Drug preparations for treating sexual dysfunction |
WO1997027745A1 (en) * | 1996-01-31 | 1997-08-07 | Technology Licensing Co. L.L.C. | Method of diagnosis and treatment and related compositions and apparatus |
US6258032B1 (en) * | 1997-01-29 | 2001-07-10 | William M. Hammesfahr | Method of diagnosis and treatment and related compositions and apparatus |
GB9608408D0 (en) | 1996-04-23 | 1996-06-26 | Adams Michael A | Treatment of erectile dysfunction |
US5797887A (en) * | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
US5958884A (en) * | 1997-04-11 | 1999-09-28 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating erectile dysfunction |
US6191156B1 (en) | 1997-04-11 | 2001-02-20 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating bladder dysfunction |
ZA989356B (en) * | 1997-10-16 | 1998-11-16 | Isis Pharma Gmbh | Pharmaceutical preparations |
US6056966A (en) * | 1998-05-18 | 2000-05-02 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for treating impotence |
US6314956B1 (en) * | 1999-09-08 | 2001-11-13 | Duke University | Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders |
US7045152B2 (en) | 1999-09-08 | 2006-05-16 | Duke University | Treating pulmonary disorders with gaseous agent causing repletion of GSNO |
CA2410632A1 (en) | 2000-06-22 | 2001-12-27 | David S. Garvey | Nitrosated and nitrosylated taxanes, compositions and methods of use |
WO2002013982A1 (en) | 2000-08-11 | 2002-02-21 | Whitlock David R | Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same |
US20020172712A1 (en) * | 2001-03-19 | 2002-11-21 | Alan Drizen | Antiemetic, anti-motion sustained release drug delivery system |
US7235523B2 (en) * | 2001-04-13 | 2007-06-26 | Children's Hospital Medical Center | Methods for the treatment of hepatic disorders |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20030138494A1 (en) * | 2001-05-15 | 2003-07-24 | L.A.M. Pharmaceutical Corporation | Drug preparations for treating sexual dysfunction |
US6676855B2 (en) * | 2001-08-02 | 2004-01-13 | Duke University | Use of a blood-flow decrease preventing agent in conjunction with insufflating gas |
US20040225275A1 (en) * | 2001-08-02 | 2004-11-11 | Reynolds James Dixon | Fetal physiology during maternal surgery or diagnosis |
US20050244382A9 (en) * | 2002-01-11 | 2005-11-03 | Whitlock David R | Compositions including ammonia oxidizing bacteria and methods of using same |
AU2003210808A1 (en) | 2002-03-06 | 2003-09-22 | Duke University | Methods and composition based on discovery of metabolism of nitroclycerin |
US7776925B2 (en) * | 2002-03-06 | 2010-08-17 | Duke University | Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria |
US20060263419A1 (en) * | 2002-03-12 | 2006-11-23 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
US8822473B2 (en) * | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
AU2003248558B8 (en) | 2002-05-21 | 2009-07-09 | Gilead Sciences, Inc. | Method of treating diabetes |
US6936639B2 (en) * | 2002-08-21 | 2005-08-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroxyl progenitors in the treatment of heart failure |
WO2005063221A1 (en) * | 2003-12-19 | 2005-07-14 | Duke University | Measuring vasodilating activity of blood samples to track disease course |
EP1865770A4 (en) * | 2005-04-07 | 2010-12-29 | Nitromed Inc | EVALUATION OF THE GENETIC RISK OF CARDIAC INSUFFICIENCY: IMPACT OF THE GENETIC VARIATION OF NOS3 |
CA2610922A1 (en) * | 2005-06-13 | 2006-12-21 | Yeda Research And Development Co. Ltd. | Use of allylmercaptocaptopril for treating or preventing obesity and obesity related diseases |
WO2007041681A2 (en) * | 2005-10-04 | 2007-04-12 | Nitromed, Inc. | Methods for treating respiratory disorders |
US8030511B2 (en) * | 2006-03-14 | 2011-10-04 | Gustafsson Lars E | Method for the manufacture of therapeutic compounds and compositions, compounds and compositions produced therewith, and their use |
US7625852B2 (en) * | 2006-06-07 | 2009-12-01 | Henry Hadry | Nail polish remover |
US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
WO2009065142A2 (en) | 2007-11-15 | 2009-05-22 | Biomedical Research Foundation Of Northwest Louisiana | Use of nitrite salts in chronic ischemia |
US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
CA2777066C (en) | 2009-10-14 | 2020-02-18 | TheraVasc, LLC | Pharmaceutical formulations of nitrite and uses thereof |
WO2011063339A1 (en) * | 2009-11-23 | 2011-05-26 | Cardioxyl Pharmaceuticals, Inc. | Nitroxyl donors for the treatment of pulmonary hypertension |
WO2011071947A2 (en) * | 2009-12-07 | 2011-06-16 | Johns Hopkins University | Bis-acylated hydroxylamine derivatives |
CA2782110A1 (en) * | 2009-12-07 | 2011-06-16 | Johns Hopkins University | N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives |
US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
WO2013009998A2 (en) | 2011-07-12 | 2013-01-17 | Pursuit Vascular, Inc. | Device for delivery of antimicrobial agent into trans-dermal catheter |
RU2015105097A (ru) * | 2012-08-23 | 2016-10-10 | Кардиолинкс Аг | Композиции аминоалкилнитрата с пролонгированным высвобождением |
EP2958573B1 (en) | 2013-02-20 | 2019-05-08 | The Board of Supervisors of the Louisiana State University Mechanical and Agricultural College | Pharmaceutical formulations of nitrite and uses thereof |
CA2946050C (en) | 2014-04-15 | 2023-08-29 | Aobiome Llc | Ammonia-oxidizing nitrosomonas eutropha strain d23 |
US11225640B2 (en) | 2014-04-15 | 2022-01-18 | Aobiome Llc | Ammonia oxidizing bacteria for treatment of psoriasis |
EP3137122B1 (en) | 2014-05-02 | 2019-09-04 | Excelsior Medical Corporation | Strip package for antiseptic cap |
JP6822978B2 (ja) | 2015-05-08 | 2021-01-27 | アイシーユー・メディカル・インコーポレーテッド | 治療薬のエミッタを受け入れるように構成された医療用コネクタ |
CA3040277A1 (en) | 2016-10-14 | 2018-04-19 | Icu Medical, Inc. | Sanitizing caps for medical connectors |
WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
AU2019384564B2 (en) | 2018-11-21 | 2023-11-23 | Icu Medical, Inc. | Antimicrobial device comprising a cap with ring and insert |
GB2579240B (en) * | 2018-11-27 | 2020-12-16 | Attgeno Ab | New processes, compositions and medical uses |
GB202007929D0 (en) * | 2020-05-27 | 2020-07-08 | Attgeno Ab | New medical uses |
WO2022072663A1 (en) * | 2020-10-01 | 2022-04-07 | Emergent Product Development Gaithersburg Inc. | Stabilized alkyl nitrite compositions |
CA3204371A1 (en) | 2020-12-07 | 2022-06-16 | Icu Medical, Inc. | Peritoneal dialysis caps, systems and methods |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3106511A (en) * | 1961-12-14 | 1963-10-08 | Revlon | Amyl nitrite inhalant composition |
CA1163195A (en) * | 1980-06-26 | 1984-03-06 | Alec D. Keith | Polymeric diffusion matrix containing a vasodilator |
US4450175A (en) * | 1982-09-23 | 1984-05-22 | Warshaw Thelma G | Method and compositions for treating acne |
DE3305690A1 (de) * | 1983-02-18 | 1984-08-30 | Heinrich Mack Nachf., 7918 Illertissen | Glycerinmononitrate zur behandlung der angina pectoris |
US4751087A (en) * | 1985-04-19 | 1988-06-14 | Riker Laboratories, Inc. | Transdermal nitroglycerin delivery system |
US4681584A (en) * | 1985-05-03 | 1987-07-21 | Alza Corporation | Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes |
US4615699A (en) * | 1985-05-03 | 1986-10-07 | Alza Corporation | Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes |
JPH06696B2 (ja) * | 1987-01-27 | 1994-01-05 | 積水化学工業株式会社 | テ−プ製剤 |
JPH06697B2 (ja) * | 1987-01-27 | 1994-01-05 | 積水化学工業株式会社 | テ−プ製剤 |
US4956181A (en) * | 1987-05-08 | 1990-09-11 | Eastman Kodak | Nitrate therapy for angina pectoris |
US5278192A (en) * | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
-
1992
- 1992-07-02 US US07/908,224 patent/US5278192A/en not_active Expired - Fee Related
-
1993
- 1993-06-30 US US08/199,280 patent/US5489610A/en not_active Expired - Fee Related
- 1993-06-30 JP JP6503397A patent/JP2729333B2/ja not_active Expired - Fee Related
- 1993-06-30 WO PCT/US1993/006235 patent/WO1994001103A1/en not_active Application Discontinuation
- 1993-06-30 CA CA002116785A patent/CA2116785C/en not_active Expired - Fee Related
- 1993-06-30 AU AU46587/93A patent/AU667948B2/en not_active Ceased
- 1993-06-30 SK SK235-94A patent/SK23594A3/sk unknown
- 1993-06-30 EP EP93916879A patent/EP0604642A1/en not_active Withdrawn
- 1993-06-30 KR KR1019940700689A patent/KR0170789B1/ko not_active IP Right Cessation
- 1993-06-30 NZ NZ254490A patent/NZ254490A/xx unknown
- 1993-06-30 CZ CZ94398A patent/CZ39894A3/cs unknown
- 1993-06-30 HU HU9400627A patent/HUT70501A/hu unknown
- 1993-06-30 PL PL93302613A patent/PL302613A1/xx unknown
- 1993-07-01 MX MX9303982A patent/MX9303982A/es not_active IP Right Cessation
- 1993-07-02 CN CN93116247A patent/CN1086997A/zh active Pending
- 1993-07-02 IL IL106217A patent/IL106217A/en not_active IP Right Cessation
- 1993-07-02 ZA ZA934771A patent/ZA934771B/xx unknown
- 1993-08-20 TW TW082106738A patent/TW261530B/zh active
-
1994
- 1994-02-28 OA OA60477A patent/OA09890A/en unknown
- 1994-02-28 NO NO940691A patent/NO305886B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO940691D0 (no) | 1994-02-28 |
JPH06510800A (ja) | 1994-12-01 |
CZ39894A3 (en) | 1994-11-16 |
TW261530B (no) | 1995-11-01 |
JP2729333B2 (ja) | 1998-03-18 |
NO305886B1 (no) | 1999-08-16 |
PL302613A1 (en) | 1994-09-05 |
EP0604642A1 (en) | 1994-07-06 |
AU667948B2 (en) | 1996-04-18 |
SK23594A3 (en) | 1994-08-10 |
CA2116785C (en) | 1998-04-07 |
CA2116785A1 (en) | 1994-01-20 |
HU9400627D0 (en) | 1994-06-28 |
KR0170789B1 (ko) | 1999-02-01 |
US5278192A (en) | 1994-01-11 |
CN1086997A (zh) | 1994-05-25 |
AU4658793A (en) | 1994-01-31 |
ZA934771B (en) | 1994-01-20 |
IL106217A0 (en) | 1993-11-15 |
NO940691L (no) | 1994-03-18 |
HUT70501A (en) | 1995-10-30 |
MX9303982A (es) | 1994-02-28 |
US5489610A (en) | 1996-02-06 |
NZ254490A (en) | 1997-08-22 |
OA09890A (en) | 1994-09-15 |
WO1994001103A1 (en) | 1994-01-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
RH1 | Patent not in force |