IL106217A - Pharmaceutical compositions containing organic nitrites for vasodilator therapy - Google Patents

Pharmaceutical compositions containing organic nitrites for vasodilator therapy

Info

Publication number
IL106217A
IL106217A IL106217A IL10621793A IL106217A IL 106217 A IL106217 A IL 106217A IL 106217 A IL106217 A IL 106217A IL 10621793 A IL10621793 A IL 10621793A IL 106217 A IL106217 A IL 106217A
Authority
IL
Israel
Prior art keywords
nitrite
dosage form
nitrites
composition
organic
Prior art date
Application number
IL106217A
Other languages
English (en)
Other versions
IL106217A0 (en
Original Assignee
Baker Norton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baker Norton Pharma filed Critical Baker Norton Pharma
Publication of IL106217A0 publication Critical patent/IL106217A0/xx
Publication of IL106217A publication Critical patent/IL106217A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL106217A 1992-07-02 1993-07-02 Pharmaceutical compositions containing organic nitrites for vasodilator therapy IL106217A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/908,224 US5278192A (en) 1992-07-02 1992-07-02 Method of vasodilator therapy for treating a patient with a condition

Publications (2)

Publication Number Publication Date
IL106217A0 IL106217A0 (en) 1993-11-15
IL106217A true IL106217A (en) 1998-04-05

Family

ID=25425396

Family Applications (1)

Application Number Title Priority Date Filing Date
IL106217A IL106217A (en) 1992-07-02 1993-07-02 Pharmaceutical compositions containing organic nitrites for vasodilator therapy

Country Status (19)

Country Link
US (2) US5278192A (es)
EP (1) EP0604642A1 (es)
JP (1) JP2729333B2 (es)
KR (1) KR0170789B1 (es)
CN (1) CN1086997A (es)
AU (1) AU667948B2 (es)
CA (1) CA2116785C (es)
CZ (1) CZ39894A3 (es)
HU (1) HUT70501A (es)
IL (1) IL106217A (es)
MX (1) MX9303982A (es)
NO (1) NO305886B1 (es)
NZ (1) NZ254490A (es)
OA (1) OA09890A (es)
PL (1) PL302613A1 (es)
SK (1) SK23594A3 (es)
TW (1) TW261530B (es)
WO (1) WO1994001103A1 (es)
ZA (1) ZA934771B (es)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278192A (en) * 1992-07-02 1994-01-11 The Research Foundation Of State University Of New York Method of vasodilator therapy for treating a patient with a condition
US5646181A (en) * 1992-07-02 1997-07-08 Research Foundation Of State University Of New York Method and compositions for treating impotence
GB9301192D0 (en) 1993-06-09 1993-06-09 Trott Francis W Flower shaped mechanised table
US5973011A (en) * 1994-03-30 1999-10-26 Isis Pharma Gmbh Pharmaceutical preparations and medicaments for the prevention and treatment of endothelial dysfunction
US5681278A (en) * 1994-06-23 1997-10-28 Cormedics Corp. Coronary vasculature treatment method
US5594032A (en) * 1994-11-10 1997-01-14 Gonzalez-Cadavid; Nestor F. Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA
US5665077A (en) * 1995-04-24 1997-09-09 Nitrosci Pharmaceuticals Llc Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
US5645839A (en) * 1995-06-07 1997-07-08 Trustees Of Boston University Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
US5658936A (en) * 1995-09-18 1997-08-19 Brigham & Women's Hospital, Inc. Enhancement of erectile function with renin-angiotensin system inhibitors
US6387407B1 (en) 1995-09-29 2002-05-14 L.A.M. Pharmaceutical Corporation Topical drug preparations
US6251436B1 (en) 1995-09-29 2001-06-26 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
US5897880A (en) 1995-09-29 1999-04-27 Lam Pharmaceuticals, Llc. Topical drug preparations
US6036977A (en) * 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
WO1997027745A1 (en) * 1996-01-31 1997-08-07 Technology Licensing Co. L.L.C. Method of diagnosis and treatment and related compositions and apparatus
US6258032B1 (en) * 1997-01-29 2001-07-10 William M. Hammesfahr Method of diagnosis and treatment and related compositions and apparatus
GB9608408D0 (en) 1996-04-23 1996-06-26 Adams Michael A Treatment of erectile dysfunction
US5797887A (en) * 1996-08-27 1998-08-25 Novovasc Llc Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
US5958884A (en) * 1997-04-11 1999-09-28 The Brigham And Women's Hospital, Inc. Compositions and methods for treating erectile dysfunction
US6191156B1 (en) 1997-04-11 2001-02-20 The Brigham And Women's Hospital, Inc. Compositions and methods for treating bladder dysfunction
ZA989356B (en) * 1997-10-16 1998-11-16 Isis Pharma Gmbh Pharmaceutical preparations
US6056966A (en) * 1998-05-18 2000-05-02 Baker Norton Pharmaceuticals, Inc. Method and compositions for treating impotence
US6314956B1 (en) * 1999-09-08 2001-11-13 Duke University Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders
US7045152B2 (en) 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
WO2002013982A1 (en) 2000-08-11 2002-02-21 Whitlock David R Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same
US20020172712A1 (en) * 2001-03-19 2002-11-21 Alan Drizen Antiemetic, anti-motion sustained release drug delivery system
US7235523B2 (en) * 2001-04-13 2007-06-26 Children's Hospital Medical Center Methods for the treatment of hepatic disorders
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030138494A1 (en) * 2001-05-15 2003-07-24 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
US6676855B2 (en) * 2001-08-02 2004-01-13 Duke University Use of a blood-flow decrease preventing agent in conjunction with insufflating gas
US20040225275A1 (en) * 2001-08-02 2004-11-11 Reynolds James Dixon Fetal physiology during maternal surgery or diagnosis
US20050244382A9 (en) * 2002-01-11 2005-11-03 Whitlock David R Compositions including ammonia oxidizing bacteria and methods of using same
AU2003210808A1 (en) 2002-03-06 2003-09-22 Duke University Methods and composition based on discovery of metabolism of nitroclycerin
US7776925B2 (en) * 2002-03-06 2010-08-17 Duke University Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
US20060263419A1 (en) * 2002-03-12 2006-11-23 Hans-Michael Wolff Transdermal therapeutic system for Parkinson's Disease
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
AU2003248558B8 (en) 2002-05-21 2009-07-09 Gilead Sciences, Inc. Method of treating diabetes
US6936639B2 (en) * 2002-08-21 2005-08-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitroxyl progenitors in the treatment of heart failure
WO2005063221A1 (en) * 2003-12-19 2005-07-14 Duke University Measuring vasodilating activity of blood samples to track disease course
EP1865770A4 (en) * 2005-04-07 2010-12-29 Nitromed Inc EVALUATION OF THE GENETIC RISK OF CARDIAC INSUFFICIENCY: IMPACT OF THE GENETIC VARIATION OF NOS3
CA2610922A1 (en) * 2005-06-13 2006-12-21 Yeda Research And Development Co. Ltd. Use of allylmercaptocaptopril for treating or preventing obesity and obesity related diseases
WO2007041681A2 (en) * 2005-10-04 2007-04-12 Nitromed, Inc. Methods for treating respiratory disorders
US8030511B2 (en) * 2006-03-14 2011-10-04 Gustafsson Lars E Method for the manufacture of therapeutic compounds and compositions, compounds and compositions produced therewith, and their use
US7625852B2 (en) * 2006-06-07 2009-12-01 Henry Hadry Nail polish remover
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
WO2009065142A2 (en) 2007-11-15 2009-05-22 Biomedical Research Foundation Of Northwest Louisiana Use of nitrite salts in chronic ischemia
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
WO2010147742A2 (en) 2009-06-18 2010-12-23 Theravasc Inc. Use of nitrite salts in treating tissue damage
CA2777066C (en) 2009-10-14 2020-02-18 TheraVasc, LLC Pharmaceutical formulations of nitrite and uses thereof
WO2011063339A1 (en) * 2009-11-23 2011-05-26 Cardioxyl Pharmaceuticals, Inc. Nitroxyl donors for the treatment of pulmonary hypertension
WO2011071947A2 (en) * 2009-12-07 2011-06-16 Johns Hopkins University Bis-acylated hydroxylamine derivatives
CA2782110A1 (en) * 2009-12-07 2011-06-16 Johns Hopkins University N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
WO2013009998A2 (en) 2011-07-12 2013-01-17 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into trans-dermal catheter
RU2015105097A (ru) * 2012-08-23 2016-10-10 Кардиолинкс Аг Композиции аминоалкилнитрата с пролонгированным высвобождением
EP2958573B1 (en) 2013-02-20 2019-05-08 The Board of Supervisors of the Louisiana State University Mechanical and Agricultural College Pharmaceutical formulations of nitrite and uses thereof
CA2946050C (en) 2014-04-15 2023-08-29 Aobiome Llc Ammonia-oxidizing nitrosomonas eutropha strain d23
US11225640B2 (en) 2014-04-15 2022-01-18 Aobiome Llc Ammonia oxidizing bacteria for treatment of psoriasis
EP3137122B1 (en) 2014-05-02 2019-09-04 Excelsior Medical Corporation Strip package for antiseptic cap
JP6822978B2 (ja) 2015-05-08 2021-01-27 アイシーユー・メディカル・インコーポレーテッド 治療薬のエミッタを受け入れるように構成された医療用コネクタ
CA3040277A1 (en) 2016-10-14 2018-04-19 Icu Medical, Inc. Sanitizing caps for medical connectors
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
AU2019384564B2 (en) 2018-11-21 2023-11-23 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
GB2579240B (en) * 2018-11-27 2020-12-16 Attgeno Ab New processes, compositions and medical uses
GB202007929D0 (en) * 2020-05-27 2020-07-08 Attgeno Ab New medical uses
WO2022072663A1 (en) * 2020-10-01 2022-04-07 Emergent Product Development Gaithersburg Inc. Stabilized alkyl nitrite compositions
CA3204371A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3106511A (en) * 1961-12-14 1963-10-08 Revlon Amyl nitrite inhalant composition
CA1163195A (en) * 1980-06-26 1984-03-06 Alec D. Keith Polymeric diffusion matrix containing a vasodilator
US4450175A (en) * 1982-09-23 1984-05-22 Warshaw Thelma G Method and compositions for treating acne
DE3305690A1 (de) * 1983-02-18 1984-08-30 Heinrich Mack Nachf., 7918 Illertissen Glycerinmononitrate zur behandlung der angina pectoris
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
US4681584A (en) * 1985-05-03 1987-07-21 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
JPH06696B2 (ja) * 1987-01-27 1994-01-05 積水化学工業株式会社 テ−プ製剤
JPH06697B2 (ja) * 1987-01-27 1994-01-05 積水化学工業株式会社 テ−プ製剤
US4956181A (en) * 1987-05-08 1990-09-11 Eastman Kodak Nitrate therapy for angina pectoris
US5278192A (en) * 1992-07-02 1994-01-11 The Research Foundation Of State University Of New York Method of vasodilator therapy for treating a patient with a condition

Also Published As

Publication number Publication date
NO940691D0 (no) 1994-02-28
JPH06510800A (ja) 1994-12-01
CZ39894A3 (en) 1994-11-16
TW261530B (es) 1995-11-01
JP2729333B2 (ja) 1998-03-18
NO305886B1 (no) 1999-08-16
PL302613A1 (en) 1994-09-05
EP0604642A1 (en) 1994-07-06
AU667948B2 (en) 1996-04-18
SK23594A3 (en) 1994-08-10
CA2116785C (en) 1998-04-07
CA2116785A1 (en) 1994-01-20
HU9400627D0 (en) 1994-06-28
KR0170789B1 (ko) 1999-02-01
US5278192A (en) 1994-01-11
CN1086997A (zh) 1994-05-25
AU4658793A (en) 1994-01-31
ZA934771B (en) 1994-01-20
IL106217A0 (en) 1993-11-15
NO940691L (no) 1994-03-18
HUT70501A (en) 1995-10-30
MX9303982A (es) 1994-02-28
US5489610A (en) 1996-02-06
NZ254490A (en) 1997-08-22
OA09890A (en) 1994-09-15
WO1994001103A1 (en) 1994-01-20

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