IL105774A - N-(substituted 2-pyridyl)-6-chloro-4-hydroxy-2-methyl-2h-thieno 2, 3-e9-1, 2-thiazine-3-carboxamide, 1, 1-dioxides their preparation and pharmaceutical compositions containing them - Google Patents

N-(substituted 2-pyridyl)-6-chloro-4-hydroxy-2-methyl-2h-thieno 2, 3-e9-1, 2-thiazine-3-carboxamide, 1, 1-dioxides their preparation and pharmaceutical compositions containing them

Info

Publication number
IL105774A
IL105774A IL10577493A IL10577493A IL105774A IL 105774 A IL105774 A IL 105774A IL 10577493 A IL10577493 A IL 10577493A IL 10577493 A IL10577493 A IL 10577493A IL 105774 A IL105774 A IL 105774A
Authority
IL
Israel
Prior art keywords
dioxides
thiazine
thieno
carboxamide
pyridyl
Prior art date
Application number
IL10577493A
Other languages
English (en)
Other versions
IL105774A0 (en
Original Assignee
Chem Pharm Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Pharm Forsch Gmbh filed Critical Chem Pharm Forsch Gmbh
Publication of IL105774A0 publication Critical patent/IL105774A0/xx
Publication of IL105774A publication Critical patent/IL105774A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL10577493A 1992-07-03 1993-05-21 N-(substituted 2-pyridyl)-6-chloro-4-hydroxy-2-methyl-2h-thieno 2, 3-e9-1, 2-thiazine-3-carboxamide, 1, 1-dioxides their preparation and pharmaceutical compositions containing them IL105774A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0136092A AT399880B (de) 1992-07-03 1992-07-03 Neue thienothiazinderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
IL105774A0 IL105774A0 (en) 1993-09-22
IL105774A true IL105774A (en) 1997-01-10

Family

ID=3512206

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10577493A IL105774A (en) 1992-07-03 1993-05-21 N-(substituted 2-pyridyl)-6-chloro-4-hydroxy-2-methyl-2h-thieno 2, 3-e9-1, 2-thiazine-3-carboxamide, 1, 1-dioxides their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US5527796A (xx)
EP (1) EP0576906A1 (xx)
JP (1) JPH06157543A (xx)
KR (1) KR940005638A (xx)
CN (1) CN1083066A (xx)
AT (1) AT399880B (xx)
AU (1) AU662229B2 (xx)
CA (1) CA2097167A1 (xx)
CZ (1) CZ129693A3 (xx)
EE (1) EE9400148A (xx)
FI (1) FI932863A (xx)
HR (1) HRP931016A2 (xx)
HU (1) HUT68733A (xx)
IL (1) IL105774A (xx)
LT (1) LT3159B (xx)
LV (1) LV10618B (xx)
MD (1) MD940297A (xx)
MY (1) MY109432A (xx)
NO (1) NO932129L (xx)
NZ (1) NZ247690A (xx)
SI (1) SI9300356A (xx)
SK (1) SK63893A3 (xx)
ZA (1) ZA933899B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400845B (de) * 1993-12-06 1996-03-25 Chem Pharm Forsch Gmbh Neue thienothiazinderivate, ein verfahren zu ihrer herstellung und ihre verwendung
EP0658559A1 (de) * 1993-12-14 1995-06-21 Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren
DE4400867A1 (de) * 1994-01-14 1995-07-20 Nycomed Arzneimittel Gmbh Neue Thienothiazinderivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
JP4533534B2 (ja) 1998-06-19 2010-09-01 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド グリコーゲンシンターゼキナーゼ3のインヒビター
WO2000025776A1 (en) 1998-10-30 2000-05-11 Nitromed, Inc. Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
CN1171892C (zh) * 2001-06-25 2004-10-20 李晶 具有抗炎镇痛活性的噻吩并噻嗪化合物及其制备方法和用途
CN111646987B (zh) * 2020-06-05 2022-06-24 湖南师范大学 一种5-氨基噻唑类非甾体抗炎化合物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1066711A (en) * 1974-08-26 1979-11-20 Hoffmann-La Roche Limited Thiophene derivatives
MC1135A1 (fr) * 1976-02-23 1977-11-18 Hoffmann La Roche Derives de thiazine
LU78009A1 (de) * 1977-08-22 1979-05-23 Hoffmann La Roche Verfahren zur herstellung von thiazinderivaten
AU518216B2 (en) 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
EP0103142B1 (de) * 1982-09-09 1987-04-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Thieno(2,3-e)-1,2-thiazin-Derivate
NZ226477A (en) * 1987-10-29 1990-07-26 Cl Pharma Substituted thieno (2,3-e)-1,2 thiazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ATA136092A (de) 1994-12-15
MY109432A (en) 1997-01-31
IL105774A0 (en) 1993-09-22
LTIP760A (en) 1994-05-15
LV10618B (en) 1996-06-20
AU662229B2 (en) 1995-08-24
JPH06157543A (ja) 1994-06-03
HU9301920D0 (en) 1993-09-28
AU4172693A (en) 1994-01-06
FI932863A (fi) 1994-01-04
KR940005638A (ko) 1994-03-22
CA2097167A1 (en) 1994-01-04
US5527796A (en) 1996-06-18
SK63893A3 (en) 1994-02-02
NO932129L (no) 1994-01-04
NO932129D0 (no) 1993-06-10
CZ129693A3 (en) 1994-01-19
MD940297A (ro) 1996-02-29
AT399880B (de) 1995-08-25
EP0576906A1 (de) 1994-01-05
EE9400148A (et) 1995-12-15
LT3159B (en) 1995-01-31
LV10618A (lv) 1995-04-20
ZA933899B (en) 1994-06-14
HUT68733A (en) 1995-07-28
SI9300356A (en) 1994-03-31
FI932863A0 (fi) 1993-06-21
CN1083066A (zh) 1994-03-02
HRP931016A2 (en) 1997-04-30
NZ247690A (en) 1994-12-22

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void