MD940297A - Noi derivaţi tienotiazinici, procedeu de obţinere a lor şi remediu farmaceutic - Google Patents

Noi derivaţi tienotiazinici, procedeu de obţinere a lor şi remediu farmaceutic

Info

Publication number
MD940297A
MD940297A MD94-0297A MD940297A MD940297A MD 940297 A MD940297 A MD 940297A MD 940297 A MD940297 A MD 940297A MD 940297 A MD940297 A MD 940297A
Authority
MD
Moldova
Prior art keywords
tienotriazine
derivatives
preparation
new
mono
Prior art date
Application number
MD94-0297A
Other languages
English (en)
Russian (ru)
Inventor
Dieter Binder
Josef Weinberger
Original Assignee
Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemisch Pharmazeutische Forschungsgesellschaft M.B.H. filed Critical Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Publication of MD940297A publication Critical patent/MD940297A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Invenţia se referă la derivaţii tienotriazinei cu formula generală I:în careX reprezintă o legătură simplă, o catenă carbonică liniară sau ramificată cu 1 - 12 atomi de C, care poate conţine una sau câteva legături duble sau triple şi/sau câţiva heteroatomi,Y reprezintă o legătură simplă,R reprezintă hidrogen, aril, -heteroaril-, arilo- xi-, heteroariloxi-, arilaza-, heteroarilaza-, ariltio-, sau heteroariltio-radical monociclic sau policiclic, uneori parţial hidratat, care poate fi substituit printr-un alchil inferior, alchil inferior mono- sau multiplu haloidat, alchil inferior perfluorat, alcoxi sau halogen, cu menţiunea că R nu este hidrogen în cazul, dacă X şi Y reprezintă o legătură simplă, precum şi la procedeul de obţinere a lor şi la utilizarea lor.
MD94-0297A 1992-07-03 1994-07-14 Noi derivaţi tienotiazinici, procedeu de obţinere a lor şi remediu farmaceutic MD940297A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0136092A AT399880B (de) 1992-07-03 1992-07-03 Neue thienothiazinderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
MD940297A true MD940297A (ro) 1996-02-29

Family

ID=3512206

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0297A MD940297A (ro) 1992-07-03 1994-07-14 Noi derivaţi tienotiazinici, procedeu de obţinere a lor şi remediu farmaceutic

Country Status (23)

Country Link
US (1) US5527796A (ro)
EP (1) EP0576906A1 (ro)
JP (1) JPH06157543A (ro)
KR (1) KR940005638A (ro)
CN (1) CN1083066A (ro)
AT (1) AT399880B (ro)
AU (1) AU662229B2 (ro)
CA (1) CA2097167A1 (ro)
CZ (1) CZ129693A3 (ro)
EE (1) EE9400148A (ro)
FI (1) FI932863A (ro)
HR (1) HRP931016A2 (ro)
HU (1) HUT68733A (ro)
IL (1) IL105774A (ro)
LT (1) LT3159B (ro)
LV (1) LV10618B (ro)
MD (1) MD940297A (ro)
MY (1) MY109432A (ro)
NO (1) NO932129L (ro)
NZ (1) NZ247690A (ro)
SI (1) SI9300356A (ro)
SK (1) SK63893A3 (ro)
ZA (1) ZA933899B (ro)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400845B (de) * 1993-12-06 1996-03-25 Chem Pharm Forsch Gmbh Neue thienothiazinderivate, ein verfahren zu ihrer herstellung und ihre verwendung
EP0658559A1 (de) * 1993-12-14 1995-06-21 Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren
DE4400867A1 (de) * 1994-01-14 1995-07-20 Nycomed Arzneimittel Gmbh Neue Thienothiazinderivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
JP4533534B2 (ja) 1998-06-19 2010-09-01 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド グリコーゲンシンターゼキナーゼ３のインヒビター
WO2000025776A1 (en) 1998-10-30 2000-05-11 Nitromed, Inc. Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
CN1171892C (zh) * 2001-06-25 2004-10-20 李晶 具有抗炎镇痛活性的噻吩并噻嗪化合物及其制备方法和用途
CN111646987B (zh) * 2020-06-05 2022-06-24 湖南师范大学 一种5-氨基噻唑类非甾体抗炎化合物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1066711A (en) * 1974-08-26 1979-11-20 Hoffmann-La Roche Limited Thiophene derivatives
MC1135A1 (fr) * 1976-02-23 1977-11-18 Hoffmann La Roche Derives de thiazine
LU78009A1 (de) * 1977-08-22 1979-05-23 Hoffmann La Roche Verfahren zur herstellung von thiazinderivaten
AU518216B2 (en) 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
EP0103142B1 (de) * 1982-09-09 1987-04-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Thieno(2,3-e)-1,2-thiazin-Derivate
NZ226477A (en) * 1987-10-29 1990-07-26 Cl Pharma Substituted thieno (2,3-e)-1,2 thiazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ATA136092A (de) 1994-12-15
MY109432A (en) 1997-01-31
IL105774A0 (en) 1993-09-22
LTIP760A (en) 1994-05-15
LV10618B (en) 1996-06-20
AU662229B2 (en) 1995-08-24
JPH06157543A (ja) 1994-06-03
HU9301920D0 (en) 1993-09-28
AU4172693A (en) 1994-01-06
FI932863A (fi) 1994-01-04
KR940005638A (ko) 1994-03-22
CA2097167A1 (en) 1994-01-04
US5527796A (en) 1996-06-18
IL105774A (en) 1997-01-10
SK63893A3 (en) 1994-02-02
NO932129L (no) 1994-01-04
NO932129D0 (no) 1993-06-10
CZ129693A3 (en) 1994-01-19
AT399880B (de) 1995-08-25
EP0576906A1 (de) 1994-01-05
EE9400148A (et) 1995-12-15
LT3159B (en) 1995-01-31
LV10618A (lv) 1995-04-20
ZA933899B (en) 1994-06-14
HUT68733A (en) 1995-07-28
SI9300356A (en) 1994-03-31
FI932863A0 (fi) 1993-06-21
CN1083066A (zh) 1994-03-02
HRP931016A2 (en) 1997-04-30
NZ247690A (en) 1994-12-22

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