LTIP119A - N-substituted heterocyclic derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
N-substituted heterocyclic derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- LTIP119A LTIP119A LTIP119A LTIP119A LTIP119A LT IP119 A LTIP119 A LT IP119A LT IP119 A LTIP119 A LT IP119A LT IP119 A LTIP119 A LT IP119A LT IP119 A LTIP119 A LT IP119A
- Authority
- LT
- Lithuania
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- substituted heterocyclic
- heterocyclic derivatives
- Prior art date
Links
- 125000000623 heterocyclic group Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9111161A FR2681067B1 (en) | 1991-09-10 | 1991-09-10 | N-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LTIP119A true LTIP119A (en) | 1994-07-15 |
| LT3148B LT3148B (en) | 1995-01-31 |
Family
ID=9416798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTIP119A LT3148B (en) | 1991-09-10 | 1992-09-08 | N-substituted heterocyclic derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0532410A1 (en) |
| JP (1) | JPH05213894A (en) |
| KR (1) | KR930006008A (en) |
| AU (1) | AU661017B2 (en) |
| CA (1) | CA2077967A1 (en) |
| CZ (1) | CZ275992A3 (en) |
| FR (1) | FR2681067B1 (en) |
| HU (1) | HUT63616A (en) |
| IL (1) | IL103116A (en) |
| LT (1) | LT3148B (en) |
| LV (1) | LV10255B (en) |
| MX (1) | MX9205155A (en) |
| MY (1) | MY108089A (en) |
| NO (1) | NO180678C (en) |
| NZ (1) | NZ244258A (en) |
| PL (1) | PL171524B1 (en) |
| RU (1) | RU2107062C1 (en) |
| TW (1) | TW218871B (en) |
| ZA (1) | ZA926899B (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992010097A1 (en) * | 1990-12-14 | 1992-06-25 | Smithkline Beecham Corporation | Angiotensin ii receptor blocking compositions |
| US5484939A (en) * | 1993-03-12 | 1996-01-16 | Lonza Ltd. | 2-substituted 5-chlorimidazoles |
| US5721263A (en) * | 1993-06-07 | 1998-02-24 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for angiotensin II-mediated diseases |
| HU218681B (en) * | 1997-07-25 | 2000-10-30 | Sanofi-Synthelabo | Process for the preparation of 1,3-diaza-spiro(4,4)non-1-en-4-one derivatives and 1-cyano-1-acylamino-cyclopentane intermediates |
| HU218680B (en) * | 1997-07-25 | 2000-10-30 | Sanofi-Synthelabo | Process for the preparation of 1,3-diaza-spiro(4,4)non-1-en-4-one derivatives and 1-cyano-1-acylamino-cyclopentane intermediates |
| US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| ES2318899T3 (en) | 1998-07-06 | 2009-05-01 | Bristol-Myers Squibb Company | BIFENIL SULFONAMIDS AS DUAL ANTAGONISTS OF ANGIOTENSIN AND ENDOTHELINE RECEPTORS. |
| DE19832429A1 (en) * | 1998-07-18 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | New imidazolylmethyl-biphenyl-sulfonylcyanamides, are sodium-dependent bicarbonate/chloride exchanger inhibitors used e.g. for treating cardiovascular disorders such as cardiac infarction |
| DE19832428A1 (en) * | 1998-07-18 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | New imidazolylmethyl-biphenyl-sulfonylcyanamides, are sodium-dependent bicarbonate/chloride exchanger inhibitors used e.g. for treating cardiovascular disorders such as cardiac infarction |
| US7091232B2 (en) * | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
| WO2004067003A1 (en) | 2003-01-31 | 2004-08-12 | Sankyo Company, Limited | Medicine for prevention of and treatment for arteriosclerosis and hypertension |
| CA2568640C (en) | 2004-06-04 | 2011-08-09 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing irbesartan |
| BRPI0609879A2 (en) * | 2005-04-28 | 2010-05-11 | Pfizer Ltd | amino acid derivatives |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CN103601792B (en) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | It is effective to the guanylate cyclase agonist of gastrointestinal dysfunction, inflammation, cancer and other diseases treatment |
| AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (en) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| EP4424697A3 (en) | 2013-06-05 | 2024-12-25 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH539640A (en) | 1970-05-29 | 1973-07-31 | Agripat Sa | Herbicidal triazines-2-substd-4-amino-6-(1'-cyclopropyl-1'-cyano - -alkyl-amino)-s-triazines |
| US4017510A (en) | 1975-11-12 | 1977-04-12 | American Cyanamid Company | Imidazoisoindolediones and the use thereof as herbicidal agents |
| DE3545597A1 (en) * | 1985-12-21 | 1987-07-02 | Celamerck Gmbh & Co Kg | NEW HERBICIDE EFFECTIVE IMIDAZOLINONES |
| EP0303863A3 (en) * | 1987-08-17 | 1991-10-23 | American Cyanamid Company | Benzenesulfonyl carboxamide compounds, intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents |
| US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
| CA2020073A1 (en) * | 1989-07-03 | 1991-01-04 | Eric E. Allen | Substituted quinazolinones as angiotensin ii antagonists |
| EP0412594B1 (en) * | 1989-07-28 | 1996-01-03 | Merck & Co. Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists |
| IL99372A0 (en) * | 1990-09-10 | 1992-08-18 | Ciba Geigy Ag | Azacyclic compounds |
| JP2004247578A (en) | 2003-02-14 | 2004-09-02 | Kawasaki Microelectronics Kk | Semiconductor device and method of manufacturing semiconductor device |
-
1991
- 1991-09-10 FR FR9111161A patent/FR2681067B1/en not_active Expired - Fee Related
-
1992
- 1992-08-26 TW TW081106738A patent/TW218871B/zh active
- 1992-09-04 CZ CS922759A patent/CZ275992A3/en unknown
- 1992-09-04 LV LVP-92-109A patent/LV10255B/en unknown
- 1992-09-04 MY MYPI92001566A patent/MY108089A/en unknown
- 1992-09-08 LT LTIP119A patent/LT3148B/en not_active IP Right Cessation
- 1992-09-08 NZ NZ244258A patent/NZ244258A/en unknown
- 1992-09-09 PL PL92295874A patent/PL171524B1/en unknown
- 1992-09-09 RU SU5052773A patent/RU2107062C1/en active
- 1992-09-09 IL IL103116A patent/IL103116A/en not_active IP Right Cessation
- 1992-09-09 EP EP92402459A patent/EP0532410A1/en not_active Withdrawn
- 1992-09-09 KR KR1019920016618A patent/KR930006008A/en not_active Ceased
- 1992-09-09 MX MX9205155A patent/MX9205155A/en unknown
- 1992-09-09 HU HU9202889A patent/HUT63616A/en unknown
- 1992-09-09 NO NO923509A patent/NO180678C/en unknown
- 1992-09-10 CA CA002077967A patent/CA2077967A1/en not_active Abandoned
- 1992-09-10 ZA ZA926899A patent/ZA926899B/en unknown
- 1992-09-10 AU AU22868/92A patent/AU661017B2/en not_active Ceased
- 1992-09-10 JP JP4242126A patent/JPH05213894A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NO923509D0 (en) | 1992-09-09 |
| AU661017B2 (en) | 1995-07-13 |
| IL103116A0 (en) | 1993-02-21 |
| NZ244258A (en) | 1996-10-28 |
| MY108089A (en) | 1996-08-15 |
| FR2681067B1 (en) | 1993-12-17 |
| TW218871B (en) | 1994-01-11 |
| RU2107062C1 (en) | 1998-03-20 |
| IL103116A (en) | 1998-04-05 |
| EP0532410A1 (en) | 1993-03-17 |
| PL295874A1 (en) | 1993-04-19 |
| HUT63616A (en) | 1993-09-28 |
| AU2286892A (en) | 1993-03-11 |
| NO180678B (en) | 1997-02-17 |
| LV10255A (en) | 1994-10-20 |
| FR2681067A1 (en) | 1993-03-12 |
| KR930006008A (en) | 1993-04-20 |
| NO923509L (en) | 1993-03-11 |
| LT3148B (en) | 1995-01-31 |
| NO180678C (en) | 1997-05-28 |
| HU9202889D0 (en) | 1992-11-30 |
| PL171524B1 (en) | 1997-05-30 |
| JPH05213894A (en) | 1993-08-24 |
| LV10255B (en) | 1995-04-20 |
| CA2077967A1 (en) | 1993-03-11 |
| MX9205155A (en) | 1993-03-01 |
| CZ275992A3 (en) | 1993-03-17 |
| ZA926899B (en) | 1993-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TK9A | Rectifications: patents |
Free format text: 1. JUNGINYS, KURIO FORMULE (I),KURIOJE:- R1 IR R2 YRA PANASUS AR SKIRTINGI, IR KIEKVIENAS NEPRIKLAUSOMAI YRA VANDENILIS ARBA PASIRINKTA GRUPE: ALKILO TARP C1-C6, ALKOKSILO TARP C1-C4, AMINAS, AMINOMETILO, KARBOKSILO, ALKOKSIKARBONILO, KURIOJE ALKOKSIGRUPE YRA TARP C1-C4, CIANAS, TETRAZOLILAS, METILTETRAZOLILAS, METILSULFONILAMINAS, TRIFLUORMETILSULFONILAMINAS, TRIFLUORMETILSULFONILAMINOMETILO GRUPE, N-CIANO ACETAMIDAS, N-HIDROKSIACETAMIDAS, N-(4-KARBOKSI-1,3-TIAZOL-2-IL)ACETAMIDAS, UREIDAS, 2-CIANGUANIDINKARBONILO GRUPE, 2-CIANGUANID |
|
| PD9A | Change of patent owner |
Free format text: SANOFI,32-34 RUE MARBEUF, 75008 PARIS,FR,19971113 |
|
| MM9A | Lapsed patents |
Effective date: 19980908 |