AU661017B2 - N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present - Google Patents
N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are presentInfo
- Publication number
- AU661017B2 AU661017B2 AU22868/92A AU2286892A AU661017B2 AU 661017 B2 AU661017 B2 AU 661017B2 AU 22868/92 A AU22868/92 A AU 22868/92A AU 2286892 A AU2286892 A AU 2286892A AU 661017 B2 AU661017 B2 AU 661017B2
- Authority
- AU
- Australia
- Prior art keywords
- preparation
- present
- pharmaceutical compositions
- substituted heterocyclic
- heterocyclic derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9111161A FR2681067B1 (en) | 1991-09-10 | 1991-09-10 | N-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. |
FR9111161 | 1991-09-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2286892A AU2286892A (en) | 1993-03-11 |
AU661017B2 true AU661017B2 (en) | 1995-07-13 |
Family
ID=9416798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU22868/92A Ceased AU661017B2 (en) | 1991-09-10 | 1992-09-10 | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0532410A1 (en) |
JP (1) | JPH05213894A (en) |
KR (1) | KR930006008A (en) |
AU (1) | AU661017B2 (en) |
CA (1) | CA2077967A1 (en) |
CZ (1) | CZ275992A3 (en) |
FR (1) | FR2681067B1 (en) |
HU (1) | HUT63616A (en) |
IL (1) | IL103116A (en) |
LT (1) | LT3148B (en) |
LV (1) | LV10255B (en) |
MX (1) | MX9205155A (en) |
MY (1) | MY108089A (en) |
NO (1) | NO180678C (en) |
NZ (1) | NZ244258A (en) |
PL (1) | PL171524B1 (en) |
RU (1) | RU2107062C1 (en) |
TW (1) | TW218871B (en) |
ZA (1) | ZA926899B (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2098176C (en) * | 1990-12-14 | 2006-12-12 | Joseph Weinstock | Angiotensin ii receptor blocking compositions |
US5484939A (en) * | 1993-03-12 | 1996-01-16 | Lonza Ltd. | 2-substituted 5-chlorimidazoles |
US5721263A (en) | 1993-06-07 | 1998-02-24 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for angiotensin II-mediated diseases |
HU218681B (en) * | 1997-07-25 | 2000-10-30 | Sanofi-Synthelabo | Process for the preparation of 1,3-diaza-spiro(4,4)non-1-en-4-one derivatives and 1-cyano-1-acylamino-cyclopentane intermediates |
HU218680B (en) * | 1997-07-25 | 2000-10-30 | Sanofi-Synthelabo | Process for the preparation of 1,3-diaza-spiro(4,4)non-1-en-4-one derivatives and 1-cyano-1-acylamino-cyclopentane intermediates |
CA2336714A1 (en) | 1998-07-06 | 2000-01-13 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
EP3045174A1 (en) | 2003-01-31 | 2016-07-20 | Daiichi Sankyo Company, Limited | Medicine for prevention of and treatment for arteriosclerosis and hypertension |
ATE493973T1 (en) | 2004-06-04 | 2011-01-15 | Teva Pharma | PHARMACEUTICAL COMPOSITION CONTAINING IRBESARTAN |
JP4173909B1 (en) * | 2005-04-28 | 2008-10-29 | ファイザー・リミテッド | Amino acid derivatives |
US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP6606491B2 (en) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | Ultra high purity agonist of guanylate cyclase C, method for producing and using the same |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6463190A (en) * | 1987-08-17 | 1991-03-14 | American Cyanamid Company | Intermediate compounds in the preparation of benzenesulfonyl carboxamide compounds and benzenesulfonyl-2- imidazolin-5-one compounds and methods of preparation thereof |
AU8375591A (en) * | 1990-09-10 | 1992-03-12 | Ciba-Geigy Ag | Azacyclic compounds |
AU646343B2 (en) * | 1991-06-27 | 1994-02-17 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds, their production and use |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH539640A (en) | 1970-05-29 | 1973-07-31 | Agripat Sa | Herbicidal triazines-2-substd-4-amino-6-(1'-cyclopropyl-1'-cyano - -alkyl-amino)-s-triazines |
US4017510A (en) | 1975-11-12 | 1977-04-12 | American Cyanamid Company | Imidazoisoindolediones and the use thereof as herbicidal agents |
DE3545597A1 (en) * | 1985-12-21 | 1987-07-02 | Celamerck Gmbh & Co Kg | NEW HERBICIDE EFFECTIVE IMIDAZOLINONES |
US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
CA2020073A1 (en) * | 1989-07-03 | 1991-01-04 | Eric E. Allen | Substituted quinazolinones as angiotensin ii antagonists |
DE69024556T2 (en) * | 1989-07-28 | 1996-10-17 | Merck & Co Inc | Substituted triazolinones, triazolinthiones and triazolinimines as angiotensin II antagonists |
JP2004247578A (en) | 2003-02-14 | 2004-09-02 | Kawasaki Microelectronics Kk | Semiconductor device and its manufacturing method |
-
1991
- 1991-09-10 FR FR9111161A patent/FR2681067B1/en not_active Expired - Fee Related
-
1992
- 1992-08-26 TW TW081106738A patent/TW218871B/zh active
- 1992-09-04 CZ CS922759A patent/CZ275992A3/en unknown
- 1992-09-04 MY MYPI92001566A patent/MY108089A/en unknown
- 1992-09-04 LV LVP-92-109A patent/LV10255B/en unknown
- 1992-09-08 LT LTIP119A patent/LT3148B/en not_active IP Right Cessation
- 1992-09-08 NZ NZ244258A patent/NZ244258A/en unknown
- 1992-09-09 MX MX9205155A patent/MX9205155A/en unknown
- 1992-09-09 EP EP92402459A patent/EP0532410A1/en not_active Withdrawn
- 1992-09-09 IL IL103116A patent/IL103116A/en not_active IP Right Cessation
- 1992-09-09 RU SU5052773A patent/RU2107062C1/en active
- 1992-09-09 NO NO923509A patent/NO180678C/en unknown
- 1992-09-09 KR KR1019920016618A patent/KR930006008A/en not_active Application Discontinuation
- 1992-09-09 HU HU9202889A patent/HUT63616A/en unknown
- 1992-09-09 PL PL92295874A patent/PL171524B1/en unknown
- 1992-09-10 CA CA002077967A patent/CA2077967A1/en not_active Abandoned
- 1992-09-10 ZA ZA926899A patent/ZA926899B/en unknown
- 1992-09-10 AU AU22868/92A patent/AU661017B2/en not_active Ceased
- 1992-09-10 JP JP4242126A patent/JPH05213894A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6463190A (en) * | 1987-08-17 | 1991-03-14 | American Cyanamid Company | Intermediate compounds in the preparation of benzenesulfonyl carboxamide compounds and benzenesulfonyl-2- imidazolin-5-one compounds and methods of preparation thereof |
AU8375591A (en) * | 1990-09-10 | 1992-03-12 | Ciba-Geigy Ag | Azacyclic compounds |
AU646343B2 (en) * | 1991-06-27 | 1994-02-17 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds, their production and use |
Also Published As
Publication number | Publication date |
---|---|
CA2077967A1 (en) | 1993-03-11 |
FR2681067A1 (en) | 1993-03-12 |
CZ275992A3 (en) | 1993-03-17 |
MY108089A (en) | 1996-08-15 |
MX9205155A (en) | 1993-03-01 |
TW218871B (en) | 1994-01-11 |
NZ244258A (en) | 1996-10-28 |
IL103116A0 (en) | 1993-02-21 |
LT3148B (en) | 1995-01-31 |
HU9202889D0 (en) | 1992-11-30 |
NO180678B (en) | 1997-02-17 |
NO923509D0 (en) | 1992-09-09 |
ZA926899B (en) | 1993-03-16 |
LV10255B (en) | 1995-04-20 |
NO180678C (en) | 1997-05-28 |
FR2681067B1 (en) | 1993-12-17 |
PL171524B1 (en) | 1997-05-30 |
NO923509L (en) | 1993-03-11 |
AU2286892A (en) | 1993-03-11 |
LTIP119A (en) | 1994-07-15 |
JPH05213894A (en) | 1993-08-24 |
LV10255A (en) | 1994-10-20 |
HUT63616A (en) | 1993-09-28 |
IL103116A (en) | 1998-04-05 |
KR930006008A (en) | 1993-04-20 |
RU2107062C1 (en) | 1998-03-20 |
EP0532410A1 (en) | 1993-03-17 |
PL295874A1 (en) | 1993-04-19 |
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