IL104657A - History of benzapine, their preparation and the pharmaceutical preparations containing them - Google Patents

History of benzapine, their preparation and the pharmaceutical preparations containing them

Info

Publication number
IL104657A
IL104657A IL10465793A IL10465793A IL104657A IL 104657 A IL104657 A IL 104657A IL 10465793 A IL10465793 A IL 10465793A IL 10465793 A IL10465793 A IL 10465793A IL 104657 A IL104657 A IL 104657A
Authority
IL
Israel
Prior art keywords
compound
tetrahydro
chloro
benzazepine
methyl
Prior art date
Application number
IL10465793A
Other languages
English (en)
Hebrew (he)
Other versions
IL104657A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL104657A0 publication Critical patent/IL104657A0/xx
Publication of IL104657A publication Critical patent/IL104657A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL10465793A 1992-02-24 1993-02-09 History of benzapine, their preparation and the pharmaceutical preparations containing them IL104657A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling

Publications (2)

Publication Number Publication Date
IL104657A0 IL104657A0 (en) 1993-06-10
IL104657A true IL104657A (en) 1999-11-30

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10465793A IL104657A (en) 1992-02-24 1993-02-09 History of benzapine, their preparation and the pharmaceutical preparations containing them

Country Status (23)

Country Link
EP (1) EP0628039B1 (fi)
JP (1) JPH07504172A (fi)
KR (1) KR100255739B1 (fi)
AT (1) ATE152450T1 (fi)
AU (1) AU667878B2 (fi)
BG (1) BG62208B1 (fi)
CA (1) CA2130678C (fi)
CZ (1) CZ288626B6 (fi)
DE (1) DE69310353T2 (fi)
DK (2) DK23392D0 (fi)
ES (1) ES2102019T3 (fi)
FI (1) FI113770B (fi)
GR (1) GR3023896T3 (fi)
HU (1) HU221314B1 (fi)
IL (1) IL104657A (fi)
NO (1) NO310193B1 (fi)
NZ (1) NZ249465A (fi)
RO (1) RO116088B1 (fi)
RU (1) RU2114839C1 (fi)
SK (1) SK281390B6 (fi)
UA (1) UA34451C2 (fi)
WO (1) WO1993017012A1 (fi)
ZA (1) ZA931099B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09510222A (ja) * 1994-03-16 1997-10-14 ノボ ノルディスク アクティーゼルスカブ ２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピン化合物の酸付加塩
BR9610162A (pt) * 1995-09-15 1999-01-05 Novo Nordisk As Compostos uso de um sal cristalino composição farmacêutica processos para a preparação de sais de adição de ácido de um composto para o tratamento de uma indicação relacionada a disfunções do sistema receptor da dopamina D-1 em um mamífero e para a fabricação de uma composição farmacêutica
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
HUE056251T2 (hu) 2012-10-25 2022-02-28 Tetra Discovery Partners Llc Heteroaril PDE4 inhibitorok
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
DE69310353T2 (de) 1997-10-02
ZA931099B (en) 1994-08-17
UA34451C2 (uk) 2001-03-15
ATE152450T1 (de) 1997-05-15
KR100255739B1 (ko) 2000-05-01
RU94040719A (ru) 1996-07-10
AU3626593A (en) 1993-09-13
SK100094A3 (en) 1995-04-12
DE69310353D1 (de) 1997-06-05
GR3023896T3 (en) 1997-09-30
DK23392D0 (da) 1992-02-24
RU2114839C1 (ru) 1998-07-10
HU9402434D0 (en) 1994-10-28
DK0628039T3 (da) 1997-12-08
NO310193B1 (no) 2001-06-05
IL104657A0 (en) 1993-06-10
HUT71127A (en) 1995-11-28
BG98993A (bg) 1995-05-31
NO943123D0 (no) 1994-08-24
BG62208B1 (bg) 1999-05-31
KR950700286A (ko) 1995-01-16
FI943875A (fi) 1994-08-23
ES2102019T3 (es) 1997-07-16
CA2130678A1 (en) 1993-08-25
AU667878B2 (en) 1996-04-18
FI943875A0 (fi) 1994-08-23
JPH07504172A (ja) 1995-05-11
NO943123L (no) 1994-08-24
CA2130678C (en) 2004-04-20
RO116088B1 (ro) 2000-10-30
CZ288626B6 (cs) 2001-08-15
EP0628039A1 (en) 1994-12-14
EP0628039B1 (en) 1997-05-02
NZ249465A (en) 1996-02-27
SK281390B6 (sk) 2001-03-12
CZ198894A3 (en) 1995-10-18
HU221314B1 (en) 2002-09-28
FI113770B (fi) 2004-06-15
WO1993017012A1 (en) 1993-09-02

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Legal Events

Date Code Title Description
FF Patent granted
HP Change in proprietorship
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees