IL104238A - History of thiazolidine, processes for their preparation and pharmaceutical preparations containing them - Google Patents
History of thiazolidine, processes for their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL104238A IL104238A IL10423892A IL10423892A IL104238A IL 104238 A IL104238 A IL 104238A IL 10423892 A IL10423892 A IL 10423892A IL 10423892 A IL10423892 A IL 10423892A IL 104238 A IL104238 A IL 104238A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- group
- formula
- carbon atoms
- thiazolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34457191 | 1991-12-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL104238A true IL104238A (en) | 1996-10-31 |
Family
ID=18370304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10423892A IL104238A (en) | 1991-12-26 | 1992-12-25 | History of thiazolidine, processes for their preparation and pharmaceutical preparations containing them |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0549365B1 (xx) |
| JP (1) | JP2833949B2 (xx) |
| CN (1) | CN1032751C (xx) |
| AT (1) | ATE126221T1 (xx) |
| AU (1) | AU654223B2 (xx) |
| CA (1) | CA2086277A1 (xx) |
| CZ (1) | CZ389792A3 (xx) |
| DE (1) | DE69204041T2 (xx) |
| DK (1) | DK0549365T3 (xx) |
| ES (1) | ES2078671T3 (xx) |
| FI (1) | FI925849A (xx) |
| GR (1) | GR3017632T3 (xx) |
| HK (1) | HK196095A (xx) |
| HU (1) | HU215450B (xx) |
| IL (1) | IL104238A (xx) |
| MX (1) | MX9207595A (xx) |
| NO (1) | NO302471B1 (xx) |
| NZ (1) | NZ245612A (xx) |
| RU (1) | RU2095354C1 (xx) |
| TW (1) | TW211007B (xx) |
| ZA (1) | ZA9210021B (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO302519B1 (no) * | 1991-12-26 | 1998-03-16 | Sankyo Co | Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat |
| EP0783888A1 (en) * | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis |
| US6331633B1 (en) * | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
| US6620830B2 (en) | 2000-04-21 | 2003-09-16 | Pfizer, Inc. | Thyroid receptor ligands |
| ATE310733T1 (de) * | 2000-04-21 | 2005-12-15 | Pfizer Prod Inc | Thyroid-rezeptorliganden |
| EP1276730A2 (en) * | 2000-04-24 | 2003-01-22 | ARYx Therapeutics | Thiazolidinedione analogues and their use for the treatment of diabetes |
| US6768008B2 (en) | 2000-04-24 | 2004-07-27 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6680387B2 (en) | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| JP2003040877A (ja) * | 2001-07-24 | 2003-02-13 | Sumika Fine Chemicals Co Ltd | ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法 |
| NZ571871A (en) | 2006-03-16 | 2011-07-29 | Metabolic Solutions Dev Co | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
| CN101454006B (zh) | 2006-03-16 | 2012-12-26 | 新陈代谢解决方案开发公司 | 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物 |
| WO2009038681A1 (en) * | 2007-09-14 | 2009-03-26 | Metabolic Solutions Development Company | Thiazolidinedione analogues for the treatment of hypertension |
| US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
| CN102753539B (zh) | 2009-12-15 | 2015-09-09 | 新陈代谢解决方案开发公司 | 治疗代谢性疾病的ppar-节制的噻唑烷二酮盐 |
| NZ602883A (en) * | 2010-04-19 | 2014-09-26 | Metabolic Solutions Dev Co Llc | Novel synthesis for thiazolidinedione compounds |
| US20130281414A1 (en) * | 2010-04-21 | 2013-10-24 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues |
| CN103180304B (zh) | 2010-08-10 | 2017-02-15 | 奥克泰塔治疗有限责任公司 | 噻唑烷二酮化合物的合成方法 |
| CN115433144B (zh) * | 2022-10-09 | 2023-09-19 | 燃点(南京)生物医药科技有限公司 | 一种脂肪酸酯类化合物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
| US5143930A (en) * | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| NO302519B1 (no) * | 1991-12-26 | 1998-03-16 | Sankyo Co | Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat |
-
1992
- 1992-12-22 NO NO924964A patent/NO302471B1/no unknown
- 1992-12-23 FI FI925849A patent/FI925849A/fi not_active Application Discontinuation
- 1992-12-23 NZ NZ245612A patent/NZ245612A/en unknown
- 1992-12-23 ZA ZA9210021A patent/ZA9210021B/xx unknown
- 1992-12-23 HU HUP9204130A patent/HU215450B/hu not_active IP Right Cessation
- 1992-12-24 DK DK92311813.7T patent/DK0549365T3/da active
- 1992-12-24 AT AT92311813T patent/ATE126221T1/de not_active IP Right Cessation
- 1992-12-24 ES ES92311813T patent/ES2078671T3/es not_active Expired - Lifetime
- 1992-12-24 EP EP92311813A patent/EP0549365B1/en not_active Expired - Lifetime
- 1992-12-24 AU AU30431/92A patent/AU654223B2/en not_active Ceased
- 1992-12-24 CA CA002086277A patent/CA2086277A1/en not_active Abandoned
- 1992-12-24 TW TW081110354A patent/TW211007B/zh active
- 1992-12-24 DE DE69204041T patent/DE69204041T2/de not_active Expired - Fee Related
- 1992-12-25 RU RU9292016231A patent/RU2095354C1/ru active
- 1992-12-25 JP JP4346122A patent/JP2833949B2/ja not_active Expired - Fee Related
- 1992-12-25 IL IL10423892A patent/IL104238A/en not_active IP Right Cessation
- 1992-12-26 CN CN92115234A patent/CN1032751C/zh not_active Expired - Fee Related
- 1992-12-28 CZ CS923897A patent/CZ389792A3/cs unknown
- 1992-12-28 MX MX9207595A patent/MX9207595A/es not_active IP Right Cessation
-
1995
- 1995-10-04 GR GR950402745T patent/GR3017632T3/el unknown
- 1995-12-28 HK HK196095A patent/HK196095A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU654223B2 (en) | 1994-10-27 |
| EP0549365A1 (en) | 1993-06-30 |
| ZA9210021B (en) | 1993-07-02 |
| CN1074680A (zh) | 1993-07-28 |
| NO924964L (no) | 1993-06-28 |
| EP0549365B1 (en) | 1995-08-09 |
| DK0549365T3 (da) | 1995-12-18 |
| NO302471B1 (no) | 1998-03-09 |
| ES2078671T3 (es) | 1995-12-16 |
| MX9207595A (es) | 1994-06-30 |
| RU2095354C1 (ru) | 1997-11-10 |
| HK196095A (en) | 1996-01-05 |
| JP2833949B2 (ja) | 1998-12-09 |
| DE69204041T2 (de) | 1996-03-28 |
| TW211007B (xx) | 1993-08-11 |
| ATE126221T1 (de) | 1995-08-15 |
| HU215450B (hu) | 1999-04-28 |
| DE69204041D1 (de) | 1995-09-14 |
| CA2086277A1 (en) | 1993-06-27 |
| GR3017632T3 (en) | 1996-01-31 |
| HUT67788A (en) | 1995-04-28 |
| FI925849A (fi) | 1993-06-27 |
| HU9204130D0 (en) | 1993-04-28 |
| FI925849A0 (fi) | 1992-12-23 |
| JPH05239041A (ja) | 1993-09-17 |
| NZ245612A (en) | 1994-06-27 |
| NO924964D0 (no) | 1992-12-22 |
| CN1032751C (zh) | 1996-09-11 |
| CZ389792A3 (en) | 1994-01-19 |
| AU3043192A (en) | 1993-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |