IL104238A - תולדות תיאזולידין, תהליכים להכנתן ותכשירי רוקחות המכילים אותן - Google Patents

תולדות תיאזולידין, תהליכים להכנתן ותכשירי רוקחות המכילים אותן

Info

Publication number
IL104238A
IL104238A IL10423892A IL10423892A IL104238A IL 104238 A IL104238 A IL 104238A IL 10423892 A IL10423892 A IL 10423892A IL 10423892 A IL10423892 A IL 10423892A IL 104238 A IL104238 A IL 104238A
Authority
IL
Israel
Prior art keywords
compound
group
formula
carbon atoms
thiazolidine
Prior art date
Application number
IL10423892A
Other languages
English (en)
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IL104238A publication Critical patent/IL104238A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL10423892A 1991-12-26 1992-12-25 תולדות תיאזולידין, תהליכים להכנתן ותכשירי רוקחות המכילים אותן IL104238A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (1)

Publication Number Publication Date
IL104238A true IL104238A (he) 1996-10-31

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10423892A IL104238A (he) 1991-12-26 1992-12-25 תולדות תיאזולידין, תהליכים להכנתן ותכשירי רוקחות המכילים אותן

Country Status (21)

Country Link
EP (1) EP0549365B1 (he)
JP (1) JP2833949B2 (he)
CN (1) CN1032751C (he)
AT (1) ATE126221T1 (he)
AU (1) AU654223B2 (he)
CA (1) CA2086277A1 (he)
CZ (1) CZ389792A3 (he)
DE (1) DE69204041T2 (he)
DK (1) DK0549365T3 (he)
ES (1) ES2078671T3 (he)
FI (1) FI925849A (he)
GR (1) GR3017632T3 (he)
HK (1) HK196095A (he)
HU (1) HU215450B (he)
IL (1) IL104238A (he)
MX (1) MX9207595A (he)
NO (1) NO302471B1 (he)
NZ (1) NZ245612A (he)
RU (1) RU2095354C1 (he)
TW (1) TW211007B (he)
ZA (1) ZA9210021B (he)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
DE60115132T2 (de) * 2000-04-21 2006-07-06 Pfizer Products Inc., Groton Thyroid-Rezeptorliganden
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
WO2001081328A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics Thiazolidinedione analogues and their use for the treatment of diabetes
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd 5−[6−(2−フルオロベンジルオキシ)−2−ナフチル]メチル−2,4−チアゾリジンジオンの製造方法及びその精製方法
PL2902026T3 (pl) 2006-03-16 2018-03-30 Metabolic Solutions Development Company Llc Analogi tiazolidynodionu do leczenia choroby metabolicznej pośredniczonej przez zapalenie
ES2388555T3 (es) 2006-03-16 2012-10-16 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
KR101537830B1 (ko) * 2007-09-14 2015-07-17 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 고혈압 치료용 티아졸리딘디온 유사체
WO2011084453A1 (en) 2009-12-15 2011-07-14 Metabolic Solutions Development Company Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases
DK2560956T3 (en) * 2010-04-19 2017-01-23 Octeta Therapeutics Llc Hitherto UNKNOWN SYNTHESIS OF THIAZOLIDE INDION COMPOUNDS
CA2796961A1 (en) * 2010-04-21 2011-10-27 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues
WO2012021476A1 (en) 2010-08-10 2012-02-16 Metabolic Solutions Development Company, Llc Novel synthesis for thiazolidinedione compounds
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
HUT67788A (en) 1995-04-28
AU3043192A (en) 1993-07-01
FI925849A0 (fi) 1992-12-23
CA2086277A1 (en) 1993-06-27
DE69204041D1 (de) 1995-09-14
NZ245612A (en) 1994-06-27
RU2095354C1 (ru) 1997-11-10
AU654223B2 (en) 1994-10-27
JPH05239041A (ja) 1993-09-17
DE69204041T2 (de) 1996-03-28
HU215450B (hu) 1999-04-28
FI925849A (fi) 1993-06-27
ZA9210021B (en) 1993-07-02
NO924964L (no) 1993-06-28
EP0549365B1 (en) 1995-08-09
HK196095A (en) 1996-01-05
MX9207595A (es) 1994-06-30
DK0549365T3 (da) 1995-12-18
HU9204130D0 (en) 1993-04-28
CZ389792A3 (en) 1994-01-19
ATE126221T1 (de) 1995-08-15
TW211007B (he) 1993-08-11
ES2078671T3 (es) 1995-12-16
GR3017632T3 (en) 1996-01-31
CN1032751C (zh) 1996-09-11
EP0549365A1 (en) 1993-06-30
JP2833949B2 (ja) 1998-12-09
NO924964D0 (no) 1992-12-22
CN1074680A (zh) 1993-07-28
NO302471B1 (no) 1998-03-09

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force