IL102575A - Chiral process and intermediates for the preparation of antidiabetic thiazoles - Google Patents
Chiral process and intermediates for the preparation of antidiabetic thiazolesInfo
- Publication number
- IL102575A IL102575A IL10257592A IL10257592A IL102575A IL 102575 A IL102575 A IL 102575A IL 10257592 A IL10257592 A IL 10257592A IL 10257592 A IL10257592 A IL 10257592A IL 102575 A IL102575 A IL 102575A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- formula
- borane
- methyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73354891A | 1991-07-22 | 1991-07-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL102575A0 IL102575A0 (en) | 1993-01-14 |
| IL102575A true IL102575A (en) | 1996-03-31 |
Family
ID=24948077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10257592A IL102575A (en) | 1991-07-22 | 1992-07-21 | Chiral process and intermediates for the preparation of antidiabetic thiazoles |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5576442A (pt) |
| EP (1) | EP0641331A1 (pt) |
| JP (1) | JP2672029B2 (pt) |
| KR (1) | KR100214907B1 (pt) |
| AU (1) | AU660187B2 (pt) |
| CA (1) | CA2111446C (pt) |
| FI (1) | FI940307A0 (pt) |
| HU (1) | HUT70422A (pt) |
| IE (1) | IE922358A1 (pt) |
| IL (1) | IL102575A (pt) |
| MX (1) | MX9204277A (pt) |
| NO (1) | NO940226D0 (pt) |
| NZ (1) | NZ243652A (pt) |
| PT (1) | PT100709B (pt) |
| TW (1) | TW199892B (pt) |
| WO (1) | WO1993002061A1 (pt) |
| ZA (1) | ZA925470B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687149B1 (fr) * | 1992-02-12 | 1995-11-03 | Roussel Uclaf | Nouveaux esters pyrethrinouides derives d'alcools thiazoliques, leur procede de preparation et leur application comme pesticides. |
| JPH08507310A (ja) * | 1993-07-16 | 1996-08-06 | ファイザー・インク． | チアゾール誘導体のエナンチオ選択的調製 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4886814A (en) * | 1986-03-13 | 1989-12-12 | Dr. Karl Thomas Gmbh | Substituted thiazoles and oxazoles and 2-hydroxy-morpholines |
| DE3621775A1 (de) * | 1986-03-13 | 1988-01-07 | Thomae Gmbh Dr K | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US4943635A (en) * | 1987-08-27 | 1990-07-24 | President & Fellows Of Harvard College | Enantioselective reduction of ketones |
| US5036079A (en) * | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| DE69227689T2 (de) * | 1991-07-22 | 1999-04-22 | Pfizer | Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzol |
-
1992
- 1992-07-01 AU AU23063/92A patent/AU660187B2/en not_active Ceased
- 1992-07-01 WO PCT/US1992/005434 patent/WO1993002061A1/en not_active Application Discontinuation
- 1992-07-01 US US08/162,036 patent/US5576442A/en not_active Expired - Fee Related
- 1992-07-01 JP JP5502811A patent/JP2672029B2/ja not_active Expired - Fee Related
- 1992-07-01 KR KR1019940700182A patent/KR100214907B1/ko not_active IP Right Cessation
- 1992-07-01 CA CA002111446A patent/CA2111446C/en not_active Expired - Fee Related
- 1992-07-01 HU HU9400187A patent/HUT70422A/hu unknown
- 1992-07-01 EP EP92914850A patent/EP0641331A1/en not_active Withdrawn
- 1992-07-07 TW TW081105397A patent/TW199892B/zh active
- 1992-07-20 PT PT100709A patent/PT100709B/pt not_active IP Right Cessation
- 1992-07-21 ZA ZA925470A patent/ZA925470B/xx unknown
- 1992-07-21 IL IL10257592A patent/IL102575A/en not_active IP Right Cessation
- 1992-07-21 IE IE235892A patent/IE922358A1/en not_active Application Discontinuation
- 1992-07-21 NZ NZ243652A patent/NZ243652A/en unknown
- 1992-07-21 MX MX9204277A patent/MX9204277A/es not_active IP Right Cessation
-
1994
- 1994-01-21 FI FI940307A patent/FI940307A0/fi unknown
- 1994-01-21 NO NO940226A patent/NO940226D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU660187B2 (en) | 1995-06-15 |
| AU2306392A (en) | 1993-02-23 |
| JPH06505026A (ja) | 1994-06-09 |
| HUT70422A (en) | 1995-10-30 |
| FI940307A (fi) | 1994-01-21 |
| IE922358A1 (en) | 1993-01-27 |
| US5576442A (en) | 1996-11-19 |
| MX9204277A (es) | 1993-02-01 |
| JP2672029B2 (ja) | 1997-11-05 |
| NO940226L (no) | 1994-01-21 |
| PT100709B (pt) | 1999-07-30 |
| NO940226D0 (no) | 1994-01-21 |
| IL102575A0 (en) | 1993-01-14 |
| FI940307A0 (fi) | 1994-01-21 |
| ZA925470B (en) | 1994-01-21 |
| EP0641331A1 (en) | 1995-03-08 |
| TW199892B (pt) | 1993-02-11 |
| KR100214907B1 (ko) | 1999-08-02 |
| HU9400187D0 (en) | 1994-05-30 |
| PT100709A (pt) | 1993-09-30 |
| NZ243652A (en) | 1994-02-25 |
| CA2111446C (en) | 1997-12-16 |
| WO1993002061A1 (en) | 1993-02-04 |
| CA2111446A1 (en) | 1993-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6037505A (en) | Enantioselective oxazaborolidine catalysts | |
| EP0640089B1 (en) | Enantioselective oxazaborolidine catalysts | |
| US5512689A (en) | Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives | |
| AU660187B2 (en) | Chiral intermediates for the preparation of antidiabetics thiazoles | |
| RU2150472C1 (ru) | Способ получения диизопинокамфеилхлорборана в реакционной смеси, способ восстановления прохирального кетона | |
| JP2001048864A (ja) | β−アドレナリン受容体アゴニストの製造用化合物と方法 | |
| Meyers et al. | Asymmetric addition to chiral aromatic and unsaturated oxazolines using a novel chiral auxiliary | |
| Wu et al. | Organolithium in Asymmetric Processes | |
| US5801247A (en) | Process for the enantioselective synthesis of hydroxypyrrolidines from amino acids and products thereof | |
| CA1247597A (en) | .beta.-LACTAMASE INHIBITING 6-(ALKOXYAMINO- METHYL)PENICILLANIC ACID 1,1-DIOXIDE AND DERIVATIVES | |
| JP5259045B2 (ja) | ベンゾプロスタサイクリン中間体、及びそれらの製造方法 | |
| US4616092A (en) | β-formyl-β-hydroxy ester | |
| DE69729206T2 (de) | Oxazolidinverbindungen und verfahren zu ihrer herstellung | |
| Cramer et al. | Reductive Asymmetric Aza-Mislow-Evans Rearrangement by 1, 3, 2-Diazaphospholene Catalysis | |
| DE69818039T2 (de) | Verfahren zur herstellung von oxiranen,aziridinen und cyclopropanen | |
| JPH0220624B2 (pt) | ||
| JPS63211289A (ja) | スルタミシリン及び同族体製造用中間体 | |
| JPS59144795A (ja) | 複素５員環燐誘導体ハロゲン化物 | |
| JPS61277673A (ja) | 新規チアゾリジン誘導体 | |
| JPS58126894A (ja) | ２−アゼチジノン誘導体の製法 | |
| JPS62209037A (ja) | α−ヒドロキシケトン誘導体の製造法 | |
| KR20040033345A (ko) | 아연 금속의 새로운 활성화 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |