IE922402A1 - Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage - Google Patents

Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage

Info

Publication number
IE922402A1
IE922402A1 IE240292A IE922402A IE922402A1 IE 922402 A1 IE922402 A1 IE 922402A1 IE 240292 A IE240292 A IE 240292A IE 922402 A IE922402 A IE 922402A IE 922402 A1 IE922402 A1 IE 922402A1
Authority
IE
Ireland
Prior art keywords
cntf
protein
recombinant
expression
peripheral nerve
Prior art date
Application number
IE240292A
Other languages
English (en)
Inventor
Franklin D Collins
Deborah Russell
John R Mcdonald
Erwin Freund
Larry J Wilhelm
Duane Mach Bonam
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IE922402A1 publication Critical patent/IE922402A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IE240292A 1991-07-23 1992-07-23 Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage IE922402A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73553891A 1991-07-23 1991-07-23
US75317691A 1991-08-30 1991-08-30

Publications (1)

Publication Number Publication Date
IE922402A1 true IE922402A1 (en) 1993-01-27

Family

ID=27112907

Family Applications (1)

Application Number Title Priority Date Filing Date
IE240292A IE922402A1 (en) 1991-07-23 1992-07-23 Purification of recombinant ciliary neurotrophic factor and¹c-terminal truncated ciliary neurotrophic factor and methods¹for treating peripheral nerve damage

Country Status (12)

Country Link
EP (1) EP0596034A4 (ja)
JP (1) JPH07500725A (ja)
AU (1) AU666327B2 (ja)
CA (1) CA2113815A1 (ja)
FI (1) FI940302A (ja)
HU (1) HUT67352A (ja)
IE (1) IE922402A1 (ja)
IL (1) IL102607A0 (ja)
MX (1) MXPA92004329A (ja)
NO (2) NO940194L (ja)
NZ (1) NZ243691A (ja)
WO (1) WO1993002206A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
IT1288388B1 (it) 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
WO1999064058A1 (fr) * 1998-06-10 1999-12-16 Bml, Inc. Preparations pour la peau et a usage externe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501914A (en) * 1893-07-25 Method of building engine-foundations
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
CA2047718A1 (en) * 1989-03-15 1990-09-16 Marston Manthorpe Purified ciliary neurotrophic factor
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
EP0446931A1 (en) * 1990-03-14 1991-09-18 FIDIA S.p.A. Human ciliary neuronotrophic factor, DNA sequence encoding the factor, and production of the factor by recombinant technology
CA2123234A1 (en) * 1991-11-11 1993-05-27 Lanfranco Callegaro Synthesis and purification of truncated and mutein forms of human ciliary neuronotrophic factor

Also Published As

Publication number Publication date
NO940194D0 (no) 1994-01-19
AU2443292A (en) 1993-02-23
FI940302A0 (fi) 1994-01-21
NO940194L (no) 1994-02-08
HUT67352A (en) 1995-03-28
CA2113815A1 (en) 1993-02-04
FI940302A (fi) 1994-01-21
WO1993002206A1 (en) 1993-02-04
EP0596034A4 (en) 1995-05-24
HU9400133D0 (en) 1994-05-30
AU666327B2 (en) 1996-02-08
NZ243691A (en) 1995-12-21
MXPA92004329A (es) 2005-04-01
JPH07500725A (ja) 1995-01-26
IL102607A0 (en) 1993-01-14
EP0596034A1 (en) 1994-05-11

Similar Documents

Publication Publication Date Title
JP2021113219A (ja) 増殖分化因子１５（ｇｄｆ−１５）の構築物
US7208466B1 (en) Use of a lectin or conjugates for modulation of c-fibre activity
HU211984A9 (en) Neuroglial derived neurothrophic factors
EA013470B1 (ru) Терапевтические агенты на основе токсичных пептидов
JPH10500693A (ja) 改変型インスリン様増殖因子
AU6048294A (en) Modified insulin-like growth factors
IL137858A (en) Modified ciliary neurotrophic factor, method of making it and methods of use thereof
PT96068B (pt) Processo para a producao de proteina biologicamente activa
JP2021525749A (ja) 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用
KR20120034927A (ko) 피부투과성 인간 상피세포 성장인자 및 그 생산방법
KR101672114B1 (ko) 항암제에서 기인하는 말초성 신경 장해성 동통의 예방 및/또는 치료제
Danse et al. On the site by which α-dendrotoxin binds to voltage-dependent potassium channels: Site-directed mutagenesis reveals that the lysine triplet 28–30 is not essential for binding
AU666327B2 (en) Purification of recombinant ciliary neurotrophic factor and C-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage
WO2008120263A2 (en) Prokineticins receptors antagonists, derivatives and uses thereof
JPWO2019228510A5 (ja)
KR102584294B1 (ko) 양친매성 세포 투과성 펩타이드 및 이의 용도
EP2275437A1 (en) Polypeptide and pharmaceutical composition containing the polypeptide
KR20060017348A (ko) 세포도입성 보톡신 융합단백질
CA2156850A1 (fr) Facteurs de croissance de la famille de l'harp, procede d'obtention et aplications
JP2968840B2 (ja) グリア由来神経栄養因子
EP1161441A1 (en) Compositions for promoting nerve regeneration

Legal Events

Date Code Title Description
FA9A Application withdrawn section 33(1)