AU666327B2 - Purification of recombinant ciliary neurotrophic factor and C-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage - Google Patents

Purification of recombinant ciliary neurotrophic factor and C-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage Download PDF

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Publication number
AU666327B2
AU666327B2 AU24432/92A AU2443292A AU666327B2 AU 666327 B2 AU666327 B2 AU 666327B2 AU 24432/92 A AU24432/92 A AU 24432/92A AU 2443292 A AU2443292 A AU 2443292A AU 666327 B2 AU666327 B2 AU 666327B2
Authority
AU
Australia
Prior art keywords
cntf
protein
recombinant
expression
peripheral nerve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU24432/92A
Other languages
English (en)
Other versions
AU2443292A (en
Inventor
Duane Mach Bonam
Franklin D. Collins
Erwin Freund
John R McDonald
Deborah Russell
Larry J Wilhelm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Synergen Neuroscience Joint Venture
Original Assignee
Syntex USA LLC
Syntex Synergen Neuroscience Joint Venture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC, Syntex Synergen Neuroscience Joint Venture filed Critical Syntex USA LLC
Publication of AU2443292A publication Critical patent/AU2443292A/en
Application granted granted Critical
Publication of AU666327B2 publication Critical patent/AU666327B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU24432/92A 1991-07-23 1992-07-21 Purification of recombinant ciliary neurotrophic factor and C-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage Ceased AU666327B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US753176 1985-07-09
US73553891A 1991-07-23 1991-07-23
US75317691A 1991-08-30 1991-08-30
PCT/US1992/006136 WO1993002206A1 (en) 1991-07-23 1992-07-21 Purification of recombinant ciliary neurotrophic factor and c-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage
US735538 1996-10-23

Publications (2)

Publication Number Publication Date
AU2443292A AU2443292A (en) 1993-02-23
AU666327B2 true AU666327B2 (en) 1996-02-08

Family

ID=27112907

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24432/92A Ceased AU666327B2 (en) 1991-07-23 1992-07-21 Purification of recombinant ciliary neurotrophic factor and C-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage

Country Status (12)

Country Link
EP (1) EP0596034A4 (ja)
JP (1) JPH07500725A (ja)
AU (1) AU666327B2 (ja)
CA (1) CA2113815A1 (ja)
FI (1) FI940302A0 (ja)
HU (1) HUT67352A (ja)
IE (1) IE922402A1 (ja)
IL (1) IL102607A0 (ja)
MX (1) MXPA92004329A (ja)
NO (2) NO940194D0 (ja)
NZ (1) NZ243691A (ja)
WO (1) WO1993002206A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
IT1288388B1 (it) 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
WO1999064058A1 (fr) * 1998-06-10 1999-12-16 Bml, Inc. Preparations pour la peau et a usage externe

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501914A (en) * 1893-07-25 Method of building engine-foundations
WO1990010647A1 (en) * 1989-03-15 1990-09-20 The Regents Of The University Of California Purified ciliary neurotrophic factor
WO1991004316A2 (en) * 1989-09-15 1991-04-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ciliary neurotrophic factor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
JPH04218374A (ja) * 1990-03-14 1992-08-07 Fidia Spa ヒト毛様体神経栄養因子
EP0668911A1 (en) * 1991-11-11 1995-08-30 FIDIA S.p.A. Synthesis and purification of truncated and mutein forms of human ciliary neuronotrophic factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501914A (en) * 1893-07-25 Method of building engine-foundations
WO1990010647A1 (en) * 1989-03-15 1990-09-20 The Regents Of The University Of California Purified ciliary neurotrophic factor
WO1991004316A2 (en) * 1989-09-15 1991-04-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ciliary neurotrophic factor

Also Published As

Publication number Publication date
EP0596034A4 (en) 1995-05-24
MXPA92004329A (es) 2005-04-01
FI940302A (fi) 1994-01-21
HUT67352A (en) 1995-03-28
IE922402A1 (en) 1993-01-27
AU2443292A (en) 1993-02-23
FI940302A0 (fi) 1994-01-21
WO1993002206A1 (en) 1993-02-04
EP0596034A1 (en) 1994-05-11
HU9400133D0 (en) 1994-05-30
NO940194D0 (no) 1994-01-19
JPH07500725A (ja) 1995-01-26
NO940194L (no) 1994-02-08
CA2113815A1 (en) 1993-02-04
NZ243691A (en) 1995-12-21
IL102607A0 (en) 1993-01-14

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