CA2113815A1 - Purification of recombinant ciliary neurotrophic factor and c-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage - Google Patents

Purification of recombinant ciliary neurotrophic factor and c-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage

Info

Publication number
CA2113815A1
CA2113815A1 CA002113815A CA2113815A CA2113815A1 CA 2113815 A1 CA2113815 A1 CA 2113815A1 CA 002113815 A CA002113815 A CA 002113815A CA 2113815 A CA2113815 A CA 2113815A CA 2113815 A1 CA2113815 A1 CA 2113815A1
Authority
CA
Canada
Prior art keywords
cntf
protein
recombinant
expression
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002113815A
Other languages
English (en)
French (fr)
Inventor
Franklin D. Collins
Deborah Russell
John R. Mcdonald
Erwin Freund
Larry J. Wilhelm
Duane M. Bonam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Synergen Neuroscience Joint Venture
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2113815A1 publication Critical patent/CA2113815A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002113815A 1991-07-23 1992-07-21 Purification of recombinant ciliary neurotrophic factor and c-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage Abandoned CA2113815A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73553891A 1991-07-23 1991-07-23
US735,538 1991-07-23
US75317691A 1991-08-30 1991-08-30
US753,176 1991-08-30

Publications (1)

Publication Number Publication Date
CA2113815A1 true CA2113815A1 (en) 1993-02-04

Family

ID=27112907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002113815A Abandoned CA2113815A1 (en) 1991-07-23 1992-07-21 Purification of recombinant ciliary neurotrophic factor and c-terminal truncated ciliary neurotrophic factor and methods for treating peripheral nerve damage

Country Status (12)

Country Link
EP (1) EP0596034A4 (ja)
JP (1) JPH07500725A (ja)
AU (1) AU666327B2 (ja)
CA (1) CA2113815A1 (ja)
FI (1) FI940302A0 (ja)
HU (1) HUT67352A (ja)
IE (1) IE922402A1 (ja)
IL (1) IL102607A0 (ja)
MX (1) MXPA92004329A (ja)
NO (2) NO940194D0 (ja)
NZ (1) NZ243691A (ja)
WO (1) WO1993002206A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
IT1288388B1 (it) 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
WO1999064058A1 (fr) * 1998-06-10 1999-12-16 Bml, Inc. Preparations pour la peau et a usage externe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501914A (en) * 1893-07-25 Method of building engine-foundations
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
JPH04503811A (ja) * 1989-03-15 1992-07-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 精製された繊毛神経親和性因子
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
JPH04218374A (ja) * 1990-03-14 1992-08-07 Fidia Spa ヒト毛様体神経栄養因子
JPH07503128A (ja) * 1991-11-11 1995-04-06 フィディーア・ソシエタ・ペル・アチオニ ヒト毛様体ニューロン親和性因子の先端欠失型および突然変異タンパク質型の合成と精製

Also Published As

Publication number Publication date
AU2443292A (en) 1993-02-23
FI940302A (fi) 1994-01-21
IL102607A0 (en) 1993-01-14
EP0596034A1 (en) 1994-05-11
NO940194D0 (no) 1994-01-19
AU666327B2 (en) 1996-02-08
FI940302A0 (fi) 1994-01-21
HUT67352A (en) 1995-03-28
MXPA92004329A (es) 2005-04-01
NZ243691A (en) 1995-12-21
NO940194L (no) 1994-02-08
WO1993002206A1 (en) 1993-02-04
IE922402A1 (en) 1993-01-27
JPH07500725A (ja) 1995-01-26
EP0596034A4 (en) 1995-05-24
HU9400133D0 (en) 1994-05-30

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Legal Events

Date Code Title Description
FZDE Discontinued