IE791411L - Cephalosporin composition - Google Patents
Cephalosporin compositionInfo
- Publication number
- IE791411L IE791411L IE791411A IE141179A IE791411L IE 791411 L IE791411 L IE 791411L IE 791411 A IE791411 A IE 791411A IE 141179 A IE141179 A IE 141179A IE 791411 L IE791411 L IE 791411L
- Authority
- IE
- Ireland
- Prior art keywords
- active agent
- salt
- surface active
- composition
- cephalosporin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
PURPOSE:A composition for rectal administration that contains a specific cephalosporin derivative, an oil base and a surface active agent, thus having improved absorption from rectum. CONSTITUTION:One of cephalosporin derivatives, which is developed by the present inventor, that is, 7-[D(-)-alpha-(4-ethyl-1-2,3-dioxo-1-piperazinyl carboxamide)- p-hydroxyphenylacetamide]-3-[5-(1-methyl-1-1, 2, 3, 4-tetrazolyl)thiomethyl]-DELTA<3>- cephem-4-carboxylic acid of the formula, or its nontoxic salt is incorporated with a nonionic surface active agent as polyoxyethylene higher alcohol ether, an anionic surface active agent as sulfate ester salt or sulfonate salt and/or bile acid salt to form said composition, which can give high concentration in blood without injection.
[JP55017342A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9000178A JPS5517342A (en) | 1978-07-25 | 1978-07-25 | Cephalosporin composition for rectal administaration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE791411L true IE791411L (en) | 1980-01-25 |
| IE48602B1 IE48602B1 (en) | 1985-03-20 |
Family
ID=13986352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1411/79A IE48602B1 (en) | 1978-07-25 | 1979-08-08 | Pharmaceutical composition for rectal administration of 7-(d(-)-alpha-(4-ethyl-2,3-dioxo-1-piperazinylcarboxamide)-p-hydroxyphenyl acetamido)-3-(5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl)-delta3-cephem-4-carboxylic acid or salts |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS5517342A (en) |
| AU (1) | AU529031B2 (en) |
| BE (1) | BE877831A (en) |
| CA (1) | CA1123738A (en) |
| CH (1) | CH641351A5 (en) |
| CS (1) | CS268651B2 (en) |
| DE (1) | DE2929840A1 (en) |
| DK (1) | DK159136C (en) |
| EG (1) | EG15790A (en) |
| ES (1) | ES482818A1 (en) |
| FI (1) | FI792303A (en) |
| FR (1) | FR2433945A1 (en) |
| GB (1) | GB2028655B (en) |
| GR (1) | GR69652B (en) |
| HU (1) | HU180965B (en) |
| IE (1) | IE48602B1 (en) |
| IL (1) | IL57846A (en) |
| IN (1) | IN151264B (en) |
| IT (1) | IT1118900B (en) |
| LU (1) | LU81546A1 (en) |
| NL (1) | NL7905708A (en) |
| NO (1) | NO792443L (en) |
| NZ (1) | NZ191053A (en) |
| PH (1) | PH16496A (en) |
| PT (1) | PT69969A (en) |
| SE (1) | SE7906340L (en) |
| ZA (1) | ZA793734B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760059A (en) * | 1985-08-05 | 1988-07-26 | Hoffmann-La Roche Inc. | Rectal dosage form |
| AT392906B (en) * | 1987-10-08 | 1991-07-10 | Hoffmann La Roche | Pharmaceutical products for oral administration |
| US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
| KR100739830B1 (en) * | 2001-03-23 | 2007-07-13 | 주식회사 하원제약 | Process for preparing Cephalosporin derivative |
| US8075910B2 (en) | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
| CN113637026A (en) * | 2020-05-11 | 2021-11-12 | 承德医学院 | Cefoperazone magnesium compound, and preparation method and application thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4950119A (en) * | 1972-09-21 | 1974-05-15 | ||
| JPS5538925B2 (en) * | 1973-11-08 | 1980-10-07 | ||
| GB1508071A (en) * | 1976-01-19 | 1978-04-19 | Toyama Chemical Co Ltd | Cephalosporins and process for producing the same |
| JPS5244222A (en) * | 1975-09-30 | 1977-04-07 | Yamanouchi Pharmaceut Co Ltd | Method of making insulin preparations for rectal application |
| JPS5822006B2 (en) * | 1975-12-12 | 1983-05-06 | 萬有製薬株式会社 | How to use this product |
| JPS6055486B2 (en) * | 1976-02-28 | 1985-12-05 | 富山化学工業株式会社 | Composition for rectal administration of a compound having a β-lactam ring |
| JPS52156918A (en) * | 1976-06-21 | 1977-12-27 | Sumitomo Chem Co Ltd | Preparation of penicillin pharmaceuticals for rectal infusion |
| JPS5619847A (en) * | 1979-07-25 | 1981-02-24 | Hitachi Ltd | Manufacturing process for discharge lamp |
-
1978
- 1978-07-25 JP JP9000178A patent/JPS5517342A/en active Pending
-
1979
- 1979-07-16 GB GB7924710A patent/GB2028655B/en not_active Expired
- 1979-07-18 NZ NZ191053A patent/NZ191053A/en unknown
- 1979-07-18 CA CA332,022A patent/CA1123738A/en not_active Expired
- 1979-07-20 IN IN747/CAL/79A patent/IN151264B/en unknown
- 1979-07-20 IL IL57846A patent/IL57846A/en unknown
- 1979-07-20 ZA ZA00793734A patent/ZA793734B/en unknown
- 1979-07-21 EG EG439/79A patent/EG15790A/en active
- 1979-07-23 CH CH680379A patent/CH641351A5/en not_active IP Right Cessation
- 1979-07-23 DE DE19792929840 patent/DE2929840A1/en active Granted
- 1979-07-23 GR GR59674A patent/GR69652B/el unknown
- 1979-07-23 HU HU79TO1112A patent/HU180965B/en unknown
- 1979-07-23 FR FR7918926A patent/FR2433945A1/en active Granted
- 1979-07-23 FI FI792303A patent/FI792303A/en not_active Application Discontinuation
- 1979-07-23 DK DK310079A patent/DK159136C/en not_active IP Right Cessation
- 1979-07-24 PH PH22810A patent/PH16496A/en unknown
- 1979-07-24 LU LU81546A patent/LU81546A1/en unknown
- 1979-07-24 AU AU49191/79A patent/AU529031B2/en not_active Expired
- 1979-07-24 NL NL7905708A patent/NL7905708A/en active Search and Examination
- 1979-07-24 CS CS795161A patent/CS268651B2/en unknown
- 1979-07-24 ES ES482818A patent/ES482818A1/en not_active Expired
- 1979-07-24 NO NO792443A patent/NO792443L/en unknown
- 1979-07-24 PT PT69969A patent/PT69969A/en unknown
- 1979-07-24 SE SE7906340A patent/SE7906340L/en not_active Application Discontinuation
- 1979-07-24 IT IT49844/79A patent/IT1118900B/en active
- 1979-07-27 BE BE0/196403A patent/BE877831A/en not_active IP Right Cessation
- 1979-08-08 IE IE1411/79A patent/IE48602B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK310079A (en) | 1980-01-26 |
| AU4919179A (en) | 1980-01-31 |
| SE7906340L (en) | 1980-01-27 |
| IL57846A0 (en) | 1979-11-30 |
| CS268651B2 (en) | 1990-04-11 |
| IT7949844A0 (en) | 1979-07-24 |
| PT69969A (en) | 1979-08-01 |
| LU81546A1 (en) | 1980-01-24 |
| GR69652B (en) | 1982-07-07 |
| PH16496A (en) | 1983-10-28 |
| CA1123738A (en) | 1982-05-18 |
| NL7905708A (en) | 1980-01-29 |
| BE877831A (en) | 1980-01-23 |
| IN151264B (en) | 1983-03-19 |
| DE2929840A1 (en) | 1980-02-14 |
| NZ191053A (en) | 1982-02-23 |
| IL57846A (en) | 1983-09-30 |
| EG15790A (en) | 1986-09-30 |
| GB2028655A (en) | 1980-03-12 |
| DE2929840C2 (en) | 1989-01-12 |
| FR2433945B1 (en) | 1984-12-14 |
| JPS5517342A (en) | 1980-02-06 |
| DK159136B (en) | 1990-09-10 |
| CH641351A5 (en) | 1984-02-29 |
| FR2433945A1 (en) | 1980-03-21 |
| ZA793734B (en) | 1980-07-30 |
| FI792303A (en) | 1980-01-26 |
| ES482818A1 (en) | 1980-09-01 |
| AU529031B2 (en) | 1983-05-26 |
| GB2028655B (en) | 1982-12-22 |
| IE48602B1 (en) | 1985-03-20 |
| NO792443L (en) | 1980-01-28 |
| CS516179A2 (en) | 1989-09-12 |
| HU180965B (en) | 1983-05-30 |
| IT1118900B (en) | 1986-03-03 |
| DK159136C (en) | 1991-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |