JPS5446840A - Antibacterial composition - Google Patents
Antibacterial compositionInfo
- Publication number
- JPS5446840A JPS5446840A JP11402077A JP11402077A JPS5446840A JP S5446840 A JPS5446840 A JP S5446840A JP 11402077 A JP11402077 A JP 11402077A JP 11402077 A JP11402077 A JP 11402077A JP S5446840 A JPS5446840 A JP S5446840A
- Authority
- JP
- Japan
- Prior art keywords
- antibacterial composition
- aminoglycoside antibiotic
- antibiotic compound
- cephalosporin analog
- phnylacetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To provide an antibacterial composition having strong synergistic effect esp. to Pseudomonas aeruginosa, and low side effects, containing a specific D(-)- cephalosporin analog and an aminoglycoside antibiotic compound.
CONSTITUTION: An antibacterial composition containing (A) a D(-)-cephalosporin analog of formula (R1 is H, OH lower alkoxycarbonyloxy, acyloxy; R2 is H, halogen nitro; R3 is lower alkyl; R4 is acetoxy, heterocylcic thio; n is 1, 2), e.g. 7-[D-(-)- α-(4-ehyl-2,3-dioxpopiperazin-2-ylcarbonylamino)-p-ethyoxycarbonyloxy-phnylacetamido]-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3cephem-4-carboxylic acid, and (B) an aminoglycoside antibiotic compound such as deoxykanamycin, amikacin, etc. The ratio of (A) to (B) is 200:1-1:2, usually 100:1-1:1, pref. 50:1-30:1.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11402077A JPS5446840A (en) | 1977-09-22 | 1977-09-22 | Antibacterial composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11402077A JPS5446840A (en) | 1977-09-22 | 1977-09-22 | Antibacterial composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5446840A true JPS5446840A (en) | 1979-04-13 |
JPS6121203B2 JPS6121203B2 (en) | 1986-05-26 |
Family
ID=14627026
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11402077A Granted JPS5446840A (en) | 1977-09-22 | 1977-09-22 | Antibacterial composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5446840A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000020009A1 (en) * | 1998-10-05 | 2000-04-13 | Kabushiki Kaisha Yakult Honsha | Antibacterial agents and process for producing the same |
AU2007200916B2 (en) * | 1998-10-05 | 2009-09-17 | Kabushiki Kaisha Yakult Honsha | Antibacterial agents and process for producing the same |
-
1977
- 1977-09-22 JP JP11402077A patent/JPS5446840A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000020009A1 (en) * | 1998-10-05 | 2000-04-13 | Kabushiki Kaisha Yakult Honsha | Antibacterial agents and process for producing the same |
US7498317B2 (en) | 1998-10-05 | 2009-03-03 | Kabushiki Kaisha Yakult Honsha | Antibacterial agents and process for producing the same |
AU2007200916B2 (en) * | 1998-10-05 | 2009-09-17 | Kabushiki Kaisha Yakult Honsha | Antibacterial agents and process for producing the same |
Also Published As
Publication number | Publication date |
---|---|
JPS6121203B2 (en) | 1986-05-26 |
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