IE57027B1 - 7-oxabicycloheptane substituted prostaglandin analogs - Google Patents

7-oxabicycloheptane substituted prostaglandin analogs

Info

Publication number
IE57027B1
IE57027B1 IE525/84A IE52584A IE57027B1 IE 57027 B1 IE57027 B1 IE 57027B1 IE 525/84 A IE525/84 A IE 525/84A IE 52584 A IE52584 A IE 52584A IE 57027 B1 IE57027 B1 IE 57027B1
Authority
IE
Ireland
Prior art keywords
prostaglandin analogs
substituted prostaglandin
oxabicycloheptane substituted
image
oxabicycloheptane
Prior art date
Application number
IE525/84A
Other languages
English (en)
Other versions
IE840525L (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE840525L publication Critical patent/IE840525L/xx
Publication of IE57027B1 publication Critical patent/IE57027B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IE525/84A 1983-03-14 1984-03-05 7-oxabicycloheptane substituted prostaglandin analogs IE57027B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15

Publications (2)

Publication Number Publication Date
IE840525L IE840525L (en) 1984-09-14
IE57027B1 true IE57027B1 (en) 1992-03-25

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
IE525/84A IE57027B1 (en) 1983-03-14 1984-03-05 7-oxabicycloheptane substituted prostaglandin analogs

Country Status (24)

Country Link
KR (1) KR840009085A (cs)
AT (1) AT383600B (cs)
AU (1) AU567919B2 (cs)
CA (1) CA1256887A (cs)
CH (1) CH658247A5 (cs)
DD (1) DD216932A5 (cs)
DE (1) DE3409124A1 (cs)
DK (1) DK155584A (cs)
ES (1) ES8506270A1 (cs)
FI (1) FI841008L (cs)
FR (1) FR2542743B1 (cs)
GB (1) GB2136428B (cs)
GR (1) GR79881B (cs)
HU (1) HU190530B (cs)
IE (1) IE57027B1 (cs)
IL (1) IL71184A0 (cs)
IT (1) IT1173442B (cs)
LU (1) LU85249A1 (cs)
NL (1) NL8400797A (cs)
NO (1) NO840960L (cs)
NZ (1) NZ207361A (cs)
PL (1) PL246663A1 (cs)
PT (1) PT78242B (cs)
SE (1) SE8401398L (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
JPS58502148A (ja) * 1981-12-23 1983-12-15 ナシヨナル　リサ−チ　デイベロツプメント　コ−ポレイシヨン プロスタグランジン
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
FI841008A7 (fi) 1984-09-15
GB2136428B (en) 1986-09-10
AU2523584A (en) 1984-09-20
SE8401398L (sv) 1984-09-15
CH658247A5 (fr) 1986-10-31
NL8400797A (nl) 1984-10-01
PL246663A1 (en) 1985-03-26
FR2542743B1 (fr) 1987-10-30
KR840009085A (ko) 1984-12-24
FI841008L (fi) 1984-09-15
NO840960L (no) 1984-09-17
PT78242A (en) 1984-04-01
SE8401398D0 (sv) 1984-03-13
ES530548A0 (es) 1985-07-01
AT383600B (de) 1987-07-27
ATA83484A (de) 1986-12-15
IT1173442B (it) 1987-06-24
PT78242B (en) 1986-05-27
IT8420049A0 (it) 1984-03-14
LU85249A1 (fr) 1984-11-14
NZ207361A (en) 1986-12-05
GR79881B (cs) 1984-10-31
IL71184A0 (en) 1984-06-29
GB2136428A (en) 1984-09-19
CA1256887A (en) 1989-07-04
HUT34179A (en) 1985-02-28
HU190530B (en) 1986-09-29
IE840525L (en) 1984-09-14
DE3409124A1 (de) 1984-09-27
DD216932A5 (de) 1985-01-02
ES8506270A1 (es) 1985-07-01
AU567919B2 (en) 1987-12-10
DK155584A (da) 1984-09-15
FI841008A0 (fi) 1984-03-13
FR2542743A1 (fr) 1984-09-21
GB8406100D0 (en) 1984-04-11
DK155584D0 (da) 1984-03-13

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