CA1271198C - 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs - Google Patents

5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Info

Publication number
CA1271198C
CA1271198C CA595286A CA595286A CA1271198C CA 1271198 C CA1271198 C CA 1271198C CA 595286 A CA595286 A CA 595286A CA 595286 A CA595286 A CA 595286A CA 1271198 C CA1271198 C CA 1271198C
Authority
CA
Canada
Prior art keywords
epoxy
prostaglandin analogs
substituted prostaglandin
oxabicycloheptane substituted
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA595286A
Other languages
French (fr)
Other versions
CA1271198A (en
Inventor
Jagabandhu Das
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/736,628 external-priority patent/US4611005A/en
Application filed filed Critical
Priority to CA595286A priority Critical patent/CA1271198C/en
Application granted granted Critical
Publication of CA1271198A publication Critical patent/CA1271198A/en
Publication of CA1271198C publication Critical patent/CA1271198C/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ABSTRACT A novel intermediate compound having the structure which is useful in the preparation of 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs having the structural formula wherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R1 is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, which are themselves cardiovascular agents useful in the treatment of thrombotic disease.
CA595286A 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs Expired CA1271198C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA595286A CA1271198C (en) 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/736,628 US4611005A (en) 1985-05-21 1985-05-21 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease
US736,628 1985-05-21
CA595286A CA1271198C (en) 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs
CA 507060 CA1270842C (en) 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA 507060 Division CA1270842C (en) 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Publications (2)

Publication Number Publication Date
CA1271198A CA1271198A (en) 1990-07-03
CA1271198C true CA1271198C (en) 1990-07-03

Family

ID=25670964

Family Applications (2)

Application Number Title Priority Date Filing Date
CA595286A Expired CA1271198C (en) 1985-05-21 1986-04-18 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs
CA000595287A Expired - Lifetime CA1270842A (en) 1985-05-21 1989-03-30 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA000595287A Expired - Lifetime CA1270842A (en) 1985-05-21 1989-03-30 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Country Status (1)

Country Link
CA (2) CA1271198C (en)

Also Published As

Publication number Publication date
CA1271198A (en) 1990-07-03
CA1270842A (en) 1990-06-26

Similar Documents

Publication Publication Date Title
JPS6426548A (en) Arylthioalkylphenylcarboxylic acid
DK165003C (en) -chlorosulfate
IT1226905B (en) COMPOUNDS OF SULPHONAMIDOTIENYLCARBOXYLIC ACID
IT8519614A0 (en) PROCEDURE TO START THE PRODUCTION REACTION OF SYNTHETIC HYDROCHLORIC ACID
YU245589A (en) Substituted semicarbazon arthropodicids
MY101618A (en) Intermediates for the production of epipodophyloxin and related compounds and processes for the preparation and use thereof
ES8506270A1 (en) 7-Oxabicycloheptane Substituted Prostaglandin Analogs
CA1270842C (en) 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs
EP0210664A3 (en) 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
CA1266668C (en) 7-oxabicycloheptane substituted oxa prostaglandin analogs
CA1267150C (en) Thiabicycloheptane substituted amino prostaglandin analogs
EP0220848A3 (en) 7-oxabicycloheptane substituted amide-carbamate prostaglandin analogs
NZ221328A (en) A synergistic combination of t-pa and a prostaglandin, being pge, or a compound of formula i
CA1271198C (en) 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs
CA1262140C (en) 7-oxabicycloheptane substituted prostaglandin alcohols
CA1268468C (en) Thiabicycloheptane substituted prostaglandin analogs
CA1267906C (en) 7-oxabicycloheptane substituted prostaglandin analogs
ES8606320A1 (en) Surfactants.
ES8506421A1 (en) Esters of 2-bromo-4-methylimidazole-5-carboxylic acid.
ATE60779T1 (en) N-GLYCOLYLNEURAMINIC ACID DERIVATIVE.
ES8603434A1 (en) 1,2,4-Triazolylpropanols, and their production and use.
DE3572171D1 (en) Theophylline-7-acetic acid ester of d,l-trans-sobrerol having mucosecretolytic-fluidizing and antibronchospastic activity, a process for its preparation and pharmaceutical compositions thereof
EP0319254A3 (en) Intermediates for the production of pyridobenzocycloheptene
EG18867A (en) Derivatives of acrylic acid useful as fungicides
DE3561620D1 (en) Nitrosoureas compounds preparation thereof and utilization thereof in anticancerous chemiotherapy

Legal Events

Date Code Title Description
MKLA Lapsed
MKLA Lapsed

Effective date: 19930105