IE57027B1 - 7-oxabicycloheptane substituted prostaglandin analogs - Google Patents

7-oxabicycloheptane substituted prostaglandin analogs

Info

Publication number
IE57027B1
IE57027B1 IE525/84A IE52584A IE57027B1 IE 57027 B1 IE57027 B1 IE 57027B1 IE 525/84 A IE525/84 A IE 525/84A IE 52584 A IE52584 A IE 52584A IE 57027 B1 IE57027 B1 IE 57027B1
Authority
IE
Ireland
Prior art keywords
prostaglandin analogs
substituted prostaglandin
oxabicycloheptane substituted
image
oxabicycloheptane
Prior art date
Application number
IE525/84A
Other languages
English (en)
Other versions
IE840525L (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE840525L publication Critical patent/IE840525L/xx
Publication of IE57027B1 publication Critical patent/IE57027B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IE525/84A 1983-03-14 1984-03-05 7-oxabicycloheptane substituted prostaglandin analogs IE57027B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15

Publications (2)

Publication Number Publication Date
IE840525L IE840525L (en) 1984-09-14
IE57027B1 true IE57027B1 (en) 1992-03-25

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
IE525/84A IE57027B1 (en) 1983-03-14 1984-03-05 7-oxabicycloheptane substituted prostaglandin analogs

Country Status (24)

Country Link
KR (1) KR840009085A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT383600B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU567919B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1256887A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH658247A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD216932A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3409124A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK155584A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8506270A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI841008A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2542743B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2136428B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR79881B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU190530B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE57027B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL71184A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1173442B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU85249A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8400797A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO840960L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ207361A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL246663A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT78242B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE8401398L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
EP0082646B1 (en) * 1981-12-23 1989-11-15 National Research Development Corporation Prostaglandins
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
CA1256887A (en) 1989-07-04
AT383600B (de) 1987-07-27
ES530548A0 (es) 1985-07-01
FR2542743B1 (fr) 1987-10-30
GB2136428B (en) 1986-09-10
DE3409124A1 (de) 1984-09-27
NL8400797A (nl) 1984-10-01
FI841008L (fi) 1984-09-15
SE8401398D0 (sv) 1984-03-13
ES8506270A1 (es) 1985-07-01
PT78242B (en) 1986-05-27
DD216932A5 (de) 1985-01-02
HU190530B (en) 1986-09-29
GB8406100D0 (en) 1984-04-11
SE8401398L (sv) 1984-09-15
AU567919B2 (en) 1987-12-10
AU2523584A (en) 1984-09-20
PT78242A (en) 1984-04-01
IT8420049A0 (it) 1984-03-14
IL71184A0 (en) 1984-06-29
IE840525L (en) 1984-09-14
FR2542743A1 (fr) 1984-09-21
GB2136428A (en) 1984-09-19
ATA83484A (de) 1986-12-15
DK155584D0 (da) 1984-03-13
GR79881B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-10-31
NZ207361A (en) 1986-12-05
IT1173442B (it) 1987-06-24
FI841008A0 (fi) 1984-03-13
PL246663A1 (en) 1985-03-26
FI841008A7 (fi) 1984-09-15
NO840960L (no) 1984-09-17
HUT34179A (en) 1985-02-28
CH658247A5 (fr) 1986-10-31
KR840009085A (ko) 1984-12-24
DK155584A (da) 1984-09-15
LU85249A1 (fr) 1984-11-14

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