ID29295A - Senyawa pirimidinona, komposisi farmasi yang mengandung senyawa tersebut dan proses penyediaannya senyawa tersebut - Google Patents
Senyawa pirimidinona, komposisi farmasi yang mengandung senyawa tersebut dan proses penyediaannya senyawa tersebutInfo
- Publication number
- ID29295A ID29295A IDW991643A ID991643A ID29295A ID 29295 A ID29295 A ID 29295A ID W991643 A IDW991643 A ID W991643A ID 991643 A ID991643 A ID 991643A ID 29295 A ID29295 A ID 29295A
- Authority
- ID
- Indonesia
- Prior art keywords
- compound
- supplying
- pharmaceutical composition
- pyrimidinone compounds
- pyrimidinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019980014821A KR19990081093A (ko) | 1998-04-25 | 1998-04-25 | 피리미디논 화합물, 이를 함유하는 약제학적 조성물 및 이의제조방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID29295A true ID29295A (id) | 2001-08-16 |
Family
ID=19536698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW991643A ID29295A (id) | 1998-04-25 | 1999-04-26 | Senyawa pirimidinona, komposisi farmasi yang mengandung senyawa tersebut dan proses penyediaannya senyawa tersebut |
Country Status (13)
Country | Link |
---|---|
US (1) | US6294542B1 (zh) |
EP (1) | EP0991627B1 (zh) |
JP (1) | JP3351539B2 (zh) |
KR (2) | KR19990081093A (zh) |
CN (1) | CN1195741C (zh) |
AU (1) | AU753424B2 (zh) |
BR (1) | BR9906373B1 (zh) |
CA (1) | CA2295446C (zh) |
DE (1) | DE69909209T2 (zh) |
ES (1) | ES2209421T3 (zh) |
ID (1) | ID29295A (zh) |
RU (1) | RU2233278C9 (zh) |
WO (1) | WO1999055681A1 (zh) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100617953B1 (ko) * | 2000-03-23 | 2006-08-30 | 보령제약 주식회사 | 피리미디논 화합물 및 이의 염의 제조방법 |
AU2001292386B2 (en) * | 2001-09-21 | 2006-06-22 | Boryung Pharmaceutical Co., Ltd. | Method for preparing pyrimidinone compound and pharmaceutically acceptable salts thereof |
KR100521980B1 (ko) * | 2002-10-10 | 2005-10-17 | 보령제약 주식회사 | 피리미디논 화합물 및 이의 염의 삼수화물의 제조 방법 |
CN104610164B (zh) * | 2010-01-21 | 2018-03-16 | 保宁制药株式会社 | 2‑(2‑正丁基‑4‑羟基‑6‑甲基‑嘧啶‑5‑基)‑n,n‑二甲基乙酰胺的制备方法 |
EA024096B1 (ru) * | 2011-04-12 | 2016-08-31 | Борюн Фармасьютикал Ко., Лтд. | Противогипертоническая фармацевтическая композиция |
KR101490329B1 (ko) * | 2012-10-12 | 2015-02-04 | 보령제약 주식회사 | 피마살탄 포타슘염의 일수화물 결정, 그 제조방법, 및 그를 포함하는 약제학적 조성물 |
KR20170006938A (ko) | 2015-07-10 | 2017-01-18 | 보령제약 주식회사 | 만성 신부전의 예방 또는 치료용 조성물 |
CN105061405A (zh) * | 2015-08-04 | 2015-11-18 | 合肥创新医药技术有限公司 | 非马沙坦钾盐三水合物的制备方法 |
KR102233673B1 (ko) | 2016-01-27 | 2021-03-30 | 보령제약 주식회사 | 당뇨병성 신장질환의 예방 또는 치료용 약학적 조성물 |
CN105837514B (zh) * | 2016-01-29 | 2018-09-18 | 北京睿创康泰医药研究院有限公司 | 非马沙坦药物杂质的制备方法 |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
KR101984121B1 (ko) * | 2017-08-21 | 2019-05-30 | 보령제약 주식회사 | 피리미디논 유도체 화합물 및 이의 용도 |
KR102078691B1 (ko) | 2017-11-30 | 2020-02-19 | 보령제약 주식회사 | 피마살탄을 포함하는 고체 분산체 |
KR102201396B1 (ko) | 2017-11-30 | 2021-01-11 | 보령제약 주식회사 | 피마살탄을 포함하는 약학적 조성물 |
KR20200073676A (ko) | 2018-12-14 | 2020-06-24 | 엠에프씨 주식회사 | 발사탄 및 사쿠비트릴을 포함하는 고체 분산체 및 이를 포함하는 약학 조성물 및 이의 제조 방법 |
CN109485640B (zh) * | 2018-12-24 | 2021-03-26 | 合肥创新医药技术有限公司 | 一种非马沙坦杂质的制备方法 |
CN112876424B (zh) * | 2019-11-29 | 2023-06-30 | 上海拓界生物医药科技有限公司 | 血管紧张素ii受体及内皮素受体双重拮抗剂 |
KR102221856B1 (ko) | 2020-10-12 | 2021-03-02 | 유니셀랩 주식회사 | 신규한 피마살탄 결정형의 다형체 |
KR20220154987A (ko) | 2021-05-14 | 2022-11-22 | 주식회사 보령 | 허혈성 뇌졸중 또는 일과성 허혈 발작을 갖는 대상체에서의 혈압 조절을 위한 약학적 조성물 |
KR20220162456A (ko) | 2021-06-01 | 2022-12-08 | 주식회사 보령 | 고혈압을 동반한 당뇨병성 신장질환의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5100897A (en) | 1989-08-28 | 1992-03-31 | Merck & Co., Inc. | Substituted pyrimidinones as angiotensin ii antagonists |
US5014228A (en) | 1989-09-21 | 1991-05-07 | Schlumberger Technologies, Inc. | Method and apparatus for calibrating linear delay lines |
JPH04120072A (ja) * | 1990-09-11 | 1992-04-21 | Meiji Seika Kaisha Ltd | アンジオテンシン2拮抗性ピリミジン誘導体 |
EP0481614A1 (en) | 1990-10-01 | 1992-04-22 | Merck & Co. Inc. | Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists |
EP0550313A1 (fr) | 1991-12-30 | 1993-07-07 | Synthelabo | Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse |
FR2688505B1 (fr) * | 1992-03-16 | 1994-05-06 | Synthelabo | Nouveau procede de preparation de 4-pyrimidinones. |
FR2700543B1 (fr) * | 1993-01-15 | 1995-03-17 | Synthelabo | Sels de dérivés de 4-pyrimidinone, leur préparation et leur application en thérapeutique. |
JPH07157485A (ja) * | 1993-12-02 | 1995-06-20 | Nkk Corp | 縮合ピリミジノン誘導体及びそれらを含有するアンジオテンシンii拮抗剤 |
KR100300566B1 (ko) | 1994-09-17 | 2001-11-22 | 조생현 | 피리미디논유도체와그의제조방법및용도 |
-
1998
- 1998-04-25 KR KR1019980014821A patent/KR19990081093A/ko not_active Application Discontinuation
-
1999
- 1999-04-26 WO PCT/KR1999/000198 patent/WO1999055681A1/en active IP Right Grant
- 1999-04-26 BR BRPI9906373-5A patent/BR9906373B1/pt not_active IP Right Cessation
- 1999-04-26 AU AU34438/99A patent/AU753424B2/en not_active Expired
- 1999-04-26 RU RU2000100785/04A patent/RU2233278C9/ru active
- 1999-04-26 DE DE69909209T patent/DE69909209T2/de not_active Expired - Lifetime
- 1999-04-26 CN CNB998006130A patent/CN1195741C/zh not_active Expired - Lifetime
- 1999-04-26 US US09/446,254 patent/US6294542B1/en not_active Expired - Lifetime
- 1999-04-26 KR KR1019997011636A patent/KR100354654B1/ko active Protection Beyond IP Right Term
- 1999-04-26 ES ES99916058T patent/ES2209421T3/es not_active Expired - Lifetime
- 1999-04-26 JP JP55398899A patent/JP3351539B2/ja not_active Expired - Lifetime
- 1999-04-26 EP EP99916058A patent/EP0991627B1/en not_active Expired - Lifetime
- 1999-04-26 ID IDW991643A patent/ID29295A/id unknown
- 1999-04-26 CA CA002295446A patent/CA2295446C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR20010013626A (ko) | 2001-02-26 |
CN1195741C (zh) | 2005-04-06 |
RU2233278C2 (ru) | 2004-07-27 |
US6294542B1 (en) | 2001-09-25 |
JP3351539B2 (ja) | 2002-11-25 |
BR9906373A (pt) | 2000-07-11 |
KR100354654B1 (ko) | 2002-09-30 |
AU3443899A (en) | 1999-11-16 |
CA2295446A1 (en) | 1999-11-04 |
JP2001508469A (ja) | 2001-06-26 |
BR9906373B1 (pt) | 2010-11-16 |
CA2295446C (en) | 2009-01-06 |
WO1999055681A1 (en) | 1999-11-04 |
DE69909209D1 (de) | 2003-08-07 |
DE69909209T2 (de) | 2004-06-03 |
AU753424B2 (en) | 2002-10-17 |
EP0991627B1 (en) | 2003-07-02 |
CN1266428A (zh) | 2000-09-13 |
ES2209421T3 (es) | 2004-06-16 |
EP0991627A1 (en) | 2000-04-12 |
KR19990081093A (ko) | 1999-11-15 |
RU2233278C9 (ru) | 2009-11-27 |
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