ID25992A - Proses untuk sintesa analog-analog nukleosida - Google Patents

Proses untuk sintesa analog-analog nukleosida

Info

Publication number
ID25992A
ID25992A IDP20000389D ID20000389D ID25992A ID 25992 A ID25992 A ID 25992A ID P20000389 D IDP20000389 D ID P20000389D ID 20000389 D ID20000389 D ID 20000389D ID 25992 A ID25992 A ID 25992A
Authority
ID
Indonesia
Prior art keywords
synthesis
analogue nucleoside
nucleoside
analogue
Prior art date
Application number
IDP20000389D
Other languages
English (en)
Indonesian (id)
Inventor
Robert William Scott
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ID25992A publication Critical patent/ID25992A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDP20000389D 1999-05-11 2000-05-10 Proses untuk sintesa analog-analog nukleosida ID25992A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13365199P 1999-05-11 1999-05-11

Publications (1)

Publication Number Publication Date
ID25992A true ID25992A (id) 2000-11-16

Family

ID=22459680

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP20000389D ID25992A (id) 1999-05-11 2000-05-10 Proses untuk sintesa analog-analog nukleosida

Country Status (22)

Country Link
US (1) US6271370B1 (th)
EP (1) EP1052264B1 (th)
JP (1) JP2001011092A (th)
KR (1) KR100403900B1 (th)
CN (1) CN1275575A (th)
AR (1) AR028991A1 (th)
AT (1) ATE291582T1 (th)
AU (1) AU3401100A (th)
BR (1) BR0002089A (th)
CA (1) CA2307951A1 (th)
CZ (1) CZ20001710A3 (th)
DE (1) DE60018833D1 (th)
HU (1) HUP0001843A3 (th)
ID (1) ID25992A (th)
IL (1) IL136027A0 (th)
IN (1) IN186850B (th)
MX (1) MXPA00004532A (th)
PL (1) PL340109A1 (th)
RU (1) RU2200738C2 (th)
TR (1) TR200001340A2 (th)
YU (1) YU25500A (th)
ZA (1) ZA200002263B (th)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
ES2386005T3 (es) * 2004-07-21 2012-08-07 Gilead Pharmasset Llc Preparación de 2-desoxi-2-fluoro-d-ribofuranosil pirimidinas y purinas sustituidas con alquilo y sus derivados
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
EP1877411B9 (en) * 2005-05-05 2012-08-29 Ardea Biosciences, Inc. Diaryl-purine, azapurines and -deazapurines as non-nucleoside reverse transcriptase inhibitors for treatment of hiv
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
CA2618089A1 (en) 2005-08-08 2007-02-15 Argenta Discovery Ltd. Bicyclo[2.2.]hept-7-ylamine derivatives and their uses
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
CA2625664C (en) 2005-10-21 2016-01-05 Novartis Ag Human antibodies against il13 and therapeutic uses
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
BRPI0717564A2 (pt) 2006-09-29 2013-10-22 Novartis Ag Pirazolopirimidinas como inibidores de pi3k lipídeo cinase
AU2007315234A1 (en) 2006-10-30 2008-05-08 Novartis Ag Heterocyclic compounds as antiinflammatory agents
PL2327693T3 (pl) 2007-12-14 2012-11-30 Pulmagen Therapeutics Asthma Ltd Indole i ich zastosowanie terapeutyczne
WO2009079412A2 (en) 2007-12-14 2009-06-25 Ardea Biosciences Inc. Reverse transcriptase inhibitors
KR20100113557A (ko) 2008-01-11 2010-10-21 노파르티스 아게 키나제 억제제로서의 피리미딘
TW201031406A (en) 2009-01-29 2010-09-01 Novartis Ag Substituted benzimidazoles for the treatment of astrocytomas
KR20110116030A (ko) 2009-02-17 2011-10-24 키에시 파르마슈티시 엣스. 피. 에이. P38 map 키나아제 억제제로서의 트리아졸로피리딘 유도체
GB0902648D0 (en) 2009-02-17 2009-04-01 Argenta Discovery Ltd Pharmaceutical compounds and compositions
US8927513B2 (en) * 2009-07-07 2015-01-06 Alnylam Pharmaceuticals, Inc. 5′ phosphate mimics
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
KR20120089643A (ko) 2009-08-12 2012-08-13 노파르티스 아게 헤테로시클릭 히드라존 화합물, 및 암 및 염증을 치료하기 위한 그의 용도
NZ620020A (en) 2009-08-17 2015-06-26 Intellikine Llc Heterocyclic compounds and uses thereof
BR112012008061A2 (pt) 2009-08-20 2016-03-01 Novartis Ag compostos de oxima heterocíclica
GB201009731D0 (en) 2010-06-10 2010-07-21 Pulmagen Therapeutics Inflamma Kinase inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
EP2673277A1 (en) 2011-02-10 2013-12-18 Novartis AG [1, 2, 4]triazolo [4, 3 -b]pyridazine compounds as inhibitors of the c-met tyrosine kinase
JP5808826B2 (ja) 2011-02-23 2015-11-10 インテリカイン, エルエルシー 複素環化合物およびその使用
JP5959541B2 (ja) 2011-02-25 2016-08-02 ノバルティス アーゲー Trk阻害剤としてのピラゾロ[1,5−a]ピリジン
WO2013038362A1 (en) 2011-09-15 2013-03-21 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
JP6130391B2 (ja) 2011-11-23 2017-05-17 インテリカイン, エルエルシー Mtor阻害剤を使用する強化された治療レジメン
CA2860479A1 (en) 2011-12-09 2013-06-13 Chiesi Farmaceutici S.P.A. Kinase inhibitors
BR112014013178A2 (pt) 2011-12-09 2017-06-13 Chiesi Farm Spa composto, composição farmacêutica e uso de um composto
CN105503861B (zh) 2011-12-09 2017-08-01 奇斯药制品公司 激酶抑制剂
EP2834246B1 (en) 2012-04-03 2021-07-28 Novartis AG Combination products with tyrosine kinase inhibitors and their use
MD20140130A2 (ro) 2012-06-29 2015-04-30 Pfizer Inc. 4-(amino-substituite)-7H-pirolo[2,3-d]pirimidine noi ca inhibitori de LRRK2
WO2014151147A1 (en) 2013-03-15 2014-09-25 Intellikine, Llc Combination of kinase inhibitors and uses thereof
AR096532A1 (es) 2013-06-06 2016-01-13 Chiesi Farm Spa Inhibidores de quinasa
MX2016002764A (es) 2013-09-05 2016-05-26 Hoffmann La Roche Compuestos de triazolopiridina, composiciones y metodos de uso de los mismos.
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Mdm2抑制劑與BRAF抑制劑之組合及其用途
CA2933767C (en) 2013-12-17 2018-11-06 Pfizer Inc. Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
US10195208B2 (en) 2014-07-31 2019-02-05 Novartis Ag Combination therapy
CN107428750A (zh) 2015-03-04 2017-12-01 豪夫迈·罗氏有限公司 三唑并吡啶化合物及其使用方法
MX377305B (es) 2015-09-14 2025-03-07 Pfizer DERIVADOS DE IMIDAZO[4,5-c]QUINOLINA E IMIDAZO[4,5-c][1,5]NAFTIRIDINA NOVEDOSOS COMO INHIBIDORES DE LRRK2.
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
AR107165A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa Inhibidores de quinasa
EP3394060A1 (en) 2015-12-23 2018-10-31 Chiesi Farmaceutici S.p.A. 1-(3-tert-butyl-2h-pyrazol-5-yl or 5-tert-butyl-isoxaol-3-yl)-3-(4-([1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalenyl) urea derivatives and their use as p38 mapk inhibitors
AR107163A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa Inhibidores de quinasa
WO2017191098A1 (en) 2016-05-05 2017-11-09 F. Hoffmann-La Roche Ag Pyrazole derivatives, compositions and therapeutic use thereof
CR20190118A (es) 2016-09-06 2019-04-30 Hoffmann La Roche COMPUESTOS 8-(AZETIDIN-1-IL)-[1,2,4]TRIAZOLO[1,5-a]PIRIDINILO, COMPOSICIONES Y MÉTODOS DE UTILIZACIPON DE LOS MISMOS
AU2017385543A1 (en) 2016-12-29 2019-05-23 F. Hoffmann-La Roche Ag Pyrazolopyrimidine compounds and methods of use thereof
JP2020510061A (ja) 2017-03-14 2020-04-02 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ピラゾロクロロフェニル化合物、組成物及びその使用方法
WO2018215389A1 (en) 2017-05-22 2018-11-29 F. Hoffmann-La Roche Ag Therapeutic compounds and compositions, and methods of use thereof
EP3630767A1 (en) 2017-05-22 2020-04-08 H. Hoffnabb-La Roche Ag Therapeutic compounds and compositions, and methods of use thereof
US10364245B2 (en) 2017-06-07 2019-07-30 Chiesi Farmaceutici S.P.A. Kinase inhibitors
CN111587250A (zh) 2018-01-15 2020-08-25 豪夫迈·罗氏有限公司 作为jak抑制剂的吡唑并嘧啶化合物
EP3801069A4 (en) 2018-06-01 2022-03-16 Cornell University MULTIPLE THERAPY FOR DISEASE OR DISORDER ASSOCIATED WITH PI3K
WO2020257142A1 (en) 2019-06-18 2020-12-24 Genentech, Inc. Tetrazole-substituted pyrazolopyrimidine inhibitors of jak kinases and uses thereof
CN114008050B (zh) 2019-06-18 2024-12-31 豪夫迈·罗氏有限公司 Jak激酶的吡唑并嘧啶芳基醚抑制剂及其用途
US11453671B2 (en) 2019-06-18 2022-09-27 Genentech, Inc. Pyrazolopyrimidine inhibitors of JAK kinases and uses thereof
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法
CN117343119A (zh) * 2022-06-29 2024-01-05 上海交通大学 一种烷基化核苷、核苷酸、寡核苷酸及其类似物的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61207400A (ja) * 1985-03-11 1986-09-13 Nippon Zoki Pharmaceut Co Ltd ヌクレオシド化合物の製造方法
US4751292A (en) 1985-07-02 1988-06-14 The Plant Cell Research Institute, Inc. Adamantyl purines
US4859677A (en) 1987-04-17 1989-08-22 University Of Kansas Nucleoside analogues having antiviral activity
US5246931A (en) 1988-10-25 1993-09-21 Bristol-Myers Squibb Company Carbocyclic nucleoside analogs
US5688778A (en) 1989-05-15 1997-11-18 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Nucleoside analogs
GB8916480D0 (en) 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
US5763596A (en) 1989-09-15 1998-06-09 Metabasis Therapeutics, Inc. C-4' modified adenosine kinase inhibitors
US5674998A (en) 1989-09-15 1997-10-07 Gensia Inc. C-4' modified adenosine kinase inhibitors
US5726302A (en) * 1989-09-15 1998-03-10 Gensia Inc. Water soluble adenosine kinase inhibitors
US5276151A (en) 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US5470857A (en) 1990-09-14 1995-11-28 Marion Merrell Dow Inc. Carbocyclic nucleoside analogs useful as immunosuppressants
SE9003151D0 (sv) 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
ZA923641B (en) 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9204015D0 (en) 1992-02-25 1992-04-08 Wellcome Found Therapeutic nucleosides
TW374087B (en) 1993-05-25 1999-11-11 Univ Yale L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents
WO1996004293A1 (en) * 1994-08-02 1996-02-15 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazoles
US5659023A (en) 1995-02-01 1997-08-19 Gilead Sciences, Inc. Nucleotide analogues
JP2001501580A (ja) 1996-01-23 2001-02-06 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 抗ウイルス剤としての修飾ベンズイミダゾールヌクレオシド

Also Published As

Publication number Publication date
CZ20001710A3 (cs) 2001-09-12
KR20010069193A (ko) 2001-07-23
ZA200002263B (en) 2001-12-24
BR0002089A (pt) 2001-01-02
EP1052264A2 (en) 2000-11-15
RU2200738C2 (ru) 2003-03-20
EP1052264B1 (en) 2005-03-23
HUP0001843A3 (en) 2001-09-28
PL340109A1 (en) 2000-11-20
ATE291582T1 (de) 2005-04-15
AR028991A1 (es) 2003-06-04
YU25500A (sh) 2003-08-29
DE60018833D1 (de) 2005-04-28
CA2307951A1 (en) 2000-11-11
TR200001340A2 (tr) 2000-12-21
HU0001843D0 (en) 2000-07-28
US6271370B1 (en) 2001-08-07
IL136027A0 (en) 2001-05-20
JP2001011092A (ja) 2001-01-16
CN1275575A (zh) 2000-12-06
EP1052264A3 (en) 2001-06-13
AU3401100A (en) 2000-11-16
MXPA00004532A (es) 2002-03-08
HUP0001843A2 (hu) 2001-06-28
KR100403900B1 (ko) 2003-11-01
IN186850B (th) 2001-11-24

Similar Documents

Publication Publication Date Title
ID25992A (id) Proses untuk sintesa analog-analog nukleosida
ID26441A (id) Proses untuk memproduksi ftalat anhidrida
ID28724A (id) Proses untuk memproduksi sikloalkanon
ID26102A (id) Proses pembuatan senyawa-senyawa stilbena
TW419101U (en) Structure of fastening apparatus for instrument
ID22641A (id) Proses pembuatan e-kaprolaktam
ID20274A (id) Proses untuk memproduksi diamina
TW470199U (en) Structure of maintaining portion for cymbals
ID24781A (id) Proses untuk memproduksi nukleotida purin
ID27091A (id) Proses untuk produksi poliol poliester rantai panjang tanpa ditingkatkan
ITMI991486A0 (it) Processo per la sintesi di citalopram
ID28601A (id) Proses penyiapan senyawa-senyawa 1,4-dihidropiridin
ID22222A (id) Proses pembuatan tiazolidinadiona tersubstitusi
ID28625A (id) Proses untuk modifikasi pektin secara enzimatik
ID24527A (id) Proses pembuatan senyawa-senyawa farmasi
ID18917A (id) Proses untuk sintesis benzotiofena
ID24927A (id) Proses sintesis zat-antara kloropurin
ITMI992423A0 (it) Procedimento di sintesi diretta di fosfuro di indio
ID22430A (id) Proses pembuatan senyawa-senyawa benzotiazolona
ID20955A (id) Proses untuk memproduksi 7-oktan-1-al
ID27404A (id) Proses asilasi
ID26021A (id) Proses untuk menyiapan 1h-indole-3-glioksamida disubstitusi-4 1h-indole-glioksamida disubstitusi-4
IL162770A (en) Process for the preparation of 7??-methyl-estr-4-ene-3-one derivatives
ID30126A (id) METODE UNTUK MENGHASILKAN SIKLO-(Asp-DPhe-NMeVal-Arg-Gly)
ID24733A (id) Proses pembuatan paroksetin hidroklorida