ID24669A - Turunan-turunan dolastatin 15 - Google Patents

Turunan-turunan dolastatin 15

Info

Publication number
ID24669A
ID24669A IDW20000322A ID20000322A ID24669A ID 24669 A ID24669 A ID 24669A ID W20000322 A IDW20000322 A ID W20000322A ID 20000322 A ID20000322 A ID 20000322A ID 24669 A ID24669 A ID 24669A
Authority
ID
Indonesia
Prior art keywords
dolastatin
Prior art date
Application number
IDW20000322A
Other languages
English (en)
Indonesian (id)
Inventor
Janssen Bernd
Barlozzari Teresa
Haupt Andreas
Zierke Thomas
Kling Andreas
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ID24669A publication Critical patent/ID24669A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20000322A 1997-07-18 1998-07-07 Turunan-turunan dolastatin 15 ID24669A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/896,394 US6143721A (en) 1997-07-18 1997-07-18 Dolastatin 15 derivatives
PCT/US1998/013901 WO1999003879A1 (en) 1997-07-18 1998-07-07 Dolastatin 15 derivatives

Publications (1)

Publication Number Publication Date
ID24669A true ID24669A (id) 2000-07-27

Family

ID=25406130

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000322A ID24669A (id) 1997-07-18 1998-07-07 Turunan-turunan dolastatin 15

Country Status (33)

Country Link
US (6) US6143721A (xx)
EP (1) EP0991658B1 (xx)
JP (4) JP4508413B2 (xx)
KR (1) KR100579748B1 (xx)
CN (1) CN1268636C (xx)
AR (1) AR018501A1 (xx)
AT (1) ATE314387T1 (xx)
AU (1) AU750120B2 (xx)
BG (1) BG65212B1 (xx)
BR (1) BR9810911A (xx)
CA (1) CA2296036C (xx)
CO (1) CO4990967A1 (xx)
CY (1) CY1107047T1 (xx)
CZ (1) CZ303045B6 (xx)
DE (1) DE69832982T2 (xx)
DK (1) DK0991658T3 (xx)
ES (1) ES2258819T3 (xx)
HK (1) HK1029125A1 (xx)
HR (1) HRP980397A2 (xx)
HU (1) HU228996B1 (xx)
ID (1) ID24669A (xx)
IL (1) IL133784A (xx)
MY (1) MY135057A (xx)
NO (1) NO326827B1 (xx)
NZ (1) NZ502296A (xx)
PL (1) PL197884B1 (xx)
PT (1) PT991658E (xx)
RU (1) RU2195462C2 (xx)
SK (1) SK286581B6 (xx)
TR (2) TR200103545T2 (xx)
TW (1) TW533217B (xx)
WO (1) WO1999003879A1 (xx)
ZA (1) ZA986358B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) * 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
WO2001058928A1 (en) * 2000-02-08 2001-08-16 Nagasawa Herbert T N-terminal d(-)-penicillamine peptides as aldehyde sequestration agents
US7256257B2 (en) * 2001-04-30 2007-08-14 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US6884869B2 (en) * 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
PL219737B1 (pl) 2002-03-22 2015-07-31 Eisai R & D Man Co Pochodne hemiasterliny, środek farmaceutyczny i zastosowanie pochodnych i zastosowanie hemiasterliny
DK1545613T3 (da) * 2002-07-31 2011-11-14 Seattle Genetics Inc Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
KR101520209B1 (ko) 2003-11-06 2015-05-13 시애틀 지네틱스, 인크. 리간드에 접합될 수 있는 모노메틸발린 화합물
US20060148014A1 (en) * 2004-12-09 2006-07-06 Sergei Agoulnik Tubulin isotype screening in cancer therapy using hemiasterlin analogs
CA2607940C (en) 2005-05-18 2009-12-15 Aegera Therapeutics Inc. Bir domain binding compounds
BRPI0711591A2 (pt) 2006-05-16 2011-11-16 Aegera Therapeutics Inc composto de ligação de domìnio bir da iap
CN111499748A (zh) 2007-07-16 2020-08-07 健泰科生物技术公司 抗cd79b抗体和免疫偶联物及使用方法
PE20090481A1 (es) 2007-07-16 2009-05-18 Genentech Inc Anticuerpos anti-cd79b e inmunoconjugados humanizados y metodos de uso
DE102007039706A1 (de) 2007-08-22 2009-02-26 Erhard Prof. Dr.-Ing. Kohn Chemischer Sensor auf Diamantschichten
EP3269737B1 (en) 2008-01-31 2024-06-19 Genentech, Inc. Anti-cd79b antibodies and immunoconjugates and methods of use
CA2784748A1 (en) * 2009-12-18 2011-06-23 Idenix Pharmaceuticals, Inc. 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
AR080154A1 (es) 2010-02-10 2012-03-14 Immunogen Inc Anticuerpos cd20 y su utilizacion
SG182724A1 (en) 2010-02-12 2012-08-30 Pharmascience Inc Iap bir domain binding compounds
US10131682B2 (en) 2012-11-24 2018-11-20 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
CN114262344A (zh) 2014-02-28 2022-04-01 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
CA3069221C (en) 2014-09-23 2023-04-04 Genentech, Inc. Methods of using anti-cd79b immunoconjugates
CA2991973C (en) 2015-07-12 2021-12-07 Suzhou M-Conj Biotech Co., Ltd. Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
KR20220150408A (ko) 2016-11-14 2022-11-10 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
JPWO2023033129A1 (xx) 2021-09-03 2023-03-09

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
SG87056A1 (en) * 1991-08-09 2002-03-19 Teikoku Hormone Mfg Co Ltd Novel tetrapeptide derivative
US5533097A (en) * 1992-02-26 1996-07-02 Motorola, Inc. Portable communication system comprising a local and wide area communication units which can store a communication when the wide area communication system is not available
US5448045A (en) * 1992-02-26 1995-09-05 Clark; Paul C. System for protecting computers via intelligent tokens or smart cards
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
IL105651A (en) * 1992-05-20 1998-07-15 Basf Ag History of dolastatin preparation and pharmaceutical preparations containing them
ATE196296T1 (de) * 1992-12-16 2000-09-15 Basf Ag Dolastatin analog
US5554993A (en) * 1994-01-04 1996-09-10 Panasonic Technologies, Inc. Global position determining system and method
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5554725A (en) * 1994-09-14 1996-09-10 Arizona Board Of Regents Acting On Behalf Of Arizona State University Synthesis of dolastatin 15
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
US5618232A (en) * 1995-03-23 1997-04-08 Martin; John R. Dual mode gaming device methods and systems
US5970143A (en) * 1995-11-22 1999-10-19 Walker Asset Management Lp Remote-auditing of computer generated outcomes, authenticated billing and access control, and software metering system using cryptographic and other protocols
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
CA2287379C (en) * 1997-01-10 2005-10-04 Silicon Gaming-Nevada Method and apparatus for providing authenticated, secure on-line communication between remote locations
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
US6554705B1 (en) * 1997-08-22 2003-04-29 Blake Cumbers Passive biometric customer identification and tracking system
US6629591B1 (en) * 2001-01-12 2003-10-07 Igt Smart token
US6438382B1 (en) * 2001-02-14 2002-08-20 Telefonaktiebolaget Lm Ericsson (Publ.) Expedited location determination in analog service areas

Also Published As

Publication number Publication date
DE69832982T2 (de) 2006-08-24
IL133784A0 (en) 2001-04-30
NZ502296A (en) 2002-02-01
JP4508413B2 (ja) 2010-07-21
BG65212B1 (bg) 2007-07-31
AR018501A1 (es) 2001-11-28
NO20000231D0 (no) 2000-01-17
JP2012211164A (ja) 2012-11-01
SK187999A3 (en) 2000-09-12
AU8475898A (en) 1999-02-10
IL133784A (en) 2005-09-25
HUP0004234A3 (en) 2001-08-28
EP0991658B1 (en) 2005-12-28
DK0991658T3 (da) 2006-05-15
EP0991658A1 (en) 2000-04-12
TR200103545T2 (tr) 2002-06-21
CZ2000176A3 (en) 2001-06-13
HK1029125A1 (en) 2001-03-23
DE69832982D1 (de) 2006-02-02
HU228996B1 (hu) 2013-07-29
TR200000132T2 (tr) 2000-05-22
ES2258819T3 (es) 2006-09-01
RU2195462C2 (ru) 2002-12-27
JP2009137967A (ja) 2009-06-25
JP5122429B2 (ja) 2013-01-16
JP5047935B2 (ja) 2012-10-10
JP2009137968A (ja) 2009-06-25
AU750120B2 (en) 2002-07-11
KR20010021998A (ko) 2001-03-15
US20030153505A1 (en) 2003-08-14
US8163698B2 (en) 2012-04-24
HUP0004234A2 (hu) 2001-05-28
BG104089A (en) 2000-12-29
TW533217B (en) 2003-05-21
WO1999003879A1 (en) 1999-01-28
ATE314387T1 (de) 2006-01-15
CY1107047T1 (el) 2012-09-26
NO20000231L (no) 2000-01-17
CO4990967A1 (es) 2000-12-26
CN1264388A (zh) 2000-08-23
PL197884B1 (pl) 2008-05-30
KR100579748B1 (ko) 2006-05-15
PL338144A1 (en) 2000-09-25
US20060270606A1 (en) 2006-11-30
HRP980397A2 (en) 1999-04-30
US6143721A (en) 2000-11-07
CA2296036C (en) 2007-05-01
CN1268636C (zh) 2006-08-09
US20130046077A1 (en) 2013-02-21
BR9810911A (pt) 2000-08-01
JP2001515010A (ja) 2001-09-18
CZ303045B6 (cs) 2012-03-07
PT991658E (pt) 2006-05-31
US7084110B2 (en) 2006-08-01
NO326827B1 (no) 2009-02-23
US6458765B1 (en) 2002-10-01
US20100099843A1 (en) 2010-04-22
SK286581B6 (sk) 2009-01-07
CA2296036A1 (en) 1999-01-28
US7662786B2 (en) 2010-02-16
MY135057A (en) 2008-01-31
ZA986358B (en) 2000-01-17

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