ID22753A - Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut - Google Patents

Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut

Info

Publication number
ID22753A
ID22753A IDW990472A ID990472A ID22753A ID 22753 A ID22753 A ID 22753A ID W990472 A IDW990472 A ID W990472A ID 990472 A ID990472 A ID 990472A ID 22753 A ID22753 A ID 22753A
Authority
ID
Indonesia
Prior art keywords
benzotiofencarcoxamide
benzotiofencarcox
carboxamide
characters
distribution
Prior art date
Application number
IDW990472A
Other languages
English (en)
Indonesian (id)
Inventor
Tsunetoshi Honbma
Yoshiharu Hiramatsu
Akinori Arimura
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of ID22753A publication Critical patent/ID22753A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
IDW990472A 1996-12-13 1997-12-10 Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut ID22753A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33349596 1996-12-13
JP25400197 1997-09-19

Publications (1)

Publication Number Publication Date
ID22753A true ID22753A (id) 1999-12-09

Family

ID=26541496

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990472A ID22753A (id) 1996-12-13 1997-12-10 Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut

Country Status (26)

Country Link
US (1) US6083974A (da)
EP (1) EP0944614B1 (da)
JP (1) JP3215441B2 (da)
KR (1) KR100433568B1 (da)
CN (2) CN1105112C (da)
AR (1) AR008939A1 (da)
AT (1) ATE223911T1 (da)
AU (1) AU718958B2 (da)
BR (1) BR9714016A (da)
CA (1) CA2274591C (da)
CZ (1) CZ297324B6 (da)
DE (1) DE69715448T2 (da)
DK (1) DK0944614T3 (da)
ES (1) ES2181039T3 (da)
HK (1) HK1020045A1 (da)
HU (1) HU226458B1 (da)
ID (1) ID22753A (da)
IL (1) IL130660A (da)
NO (1) NO992838L (da)
NZ (1) NZ336143A (da)
PL (1) PL191760B1 (da)
PT (1) PT944614E (da)
RU (1) RU2161617C1 (da)
TR (1) TR199901280T2 (da)
TW (1) TW438790B (da)
WO (1) WO1998025919A1 (da)

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CA2326418A1 (en) 1998-03-31 1999-10-07 Shionogi & Co., Ltd. Process for preparing benzothiophenecarboxamide derivatives
ES2244179T3 (es) * 1998-03-31 2005-12-01 SHIONOGI & CO., LTD. Proceso para la preparacion de derivados de acido 5-hidroxibenzo(b)tiofen-3-carboxilico.
JP3857525B2 (ja) * 1998-06-03 2006-12-13 塩野義製薬株式会社 Ｐｇｄ２拮抗剤を含有する痒みの治療剤
JP3730170B2 (ja) 1999-07-02 2005-12-21 塩野義製薬株式会社 ビシクロ環系アミノアルコールの新規な製造法
CA2402174A1 (en) 2000-03-09 2001-09-13 Ono Pharmaceutical Co., Ltd. Indole derivatives, process for preparation of the same and use thereof
EP1274457B1 (en) * 2000-04-12 2005-11-30 Merck Frosst Canada & Co. Method and compositions for the treatment of allergic conditions using pgd2 receptor antagonists
US6410583B1 (en) * 2000-07-25 2002-06-25 Merck Frosst Canada & Co. Cyclopentanoindoles, compositions containing such compounds and methods of treatment
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
DE60108515T2 (de) 2000-10-17 2006-01-12 Shionogi & Co., Ltd. Verfahren zur herstellung eines pgd2-antagonisten
AU2001296013A1 (en) * 2000-11-01 2002-05-15 Shionogi And Co., Ltd. Pgd2 receptor antagonistic pharmaceutical compositions
AR038136A1 (es) 2002-01-24 2004-12-29 Merck Frosst Canada Inc Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
WO2003078409A1 (fr) 2002-03-19 2003-09-25 Ono Pharmaceutical Co., Ltd. Composes d'acide carboxylique et medicaments renfermant les composes comme principe actif
WO2004006956A1 (ja) * 2002-07-12 2004-01-22 Japan Science And Technology Agency 脳損傷の予後改善薬とそのスクリーニング方法
WO2004030674A1 (ja) * 2002-09-30 2004-04-15 Shionogi & Co., Ltd. プロスタグランジンｄ２、プロスタグランジンｄ２アゴニストおよびプロスタグランジンｄ２アンタゴニストの新規用途
JP4332151B2 (ja) 2002-10-30 2009-09-16 メルク フロスト カナダ リミテツド ピリドピロリジンおよびピリドインドリジン誘導体
DK1725553T3 (da) 2004-03-11 2008-08-18 Actelion Pharmaceuticals Ltd Tetrahydropyridoindolderivater
JPWO2006068162A1 (ja) * 2004-12-24 2008-06-12 塩野義製薬株式会社 慢性閉塞性肺疾患の治療剤
TW200716093A (en) * 2005-04-28 2007-05-01 Shionogi & Co An antiasthmatic agent containing PGD2 receptor antagonist and leukotriene receptor antagonist
TWI410410B (zh) 2007-08-10 2013-10-01 Ono Pharmaceutical Co Phenylacetic acid compounds
AR079492A1 (es) 2009-12-23 2012-02-01 Ironwood Pharmaceuticals Inc Moduladores de crth2
US20130178475A1 (en) 2010-03-17 2013-07-11 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
JP5860459B2 (ja) 2010-06-30 2016-02-16 アイアンウッド ファーマシューティカルズ インコーポレイテッド ｓＧＣ刺激薬
US20130216552A1 (en) 2010-07-12 2013-08-22 Ironwood Pharmaceuticals, Inc. Crth2 modulators
WO2012009134A1 (en) 2010-07-12 2012-01-19 Ironwood Pharmaceuticals, Inc. Crth2 modulators
CN103402515B (zh) 2010-11-09 2017-05-17 铁木医药有限公司 sGC刺激剂
WO2013101830A1 (en) 2011-12-27 2013-07-04 Ironwood Pharmaceuticals, Inc. 2 - benzyl, 3 - (pyrimidin- 2 -yl) substituted pyrazoles useful as sgc stimulators
WO2014047111A1 (en) 2012-09-18 2014-03-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
EP2897953B8 (en) 2012-09-19 2019-06-26 Cyclerion Therapeutics, Inc. Sgc stimulators
RS59981B1 (sr) 2013-03-15 2020-03-31 Cyclerion Therapeutics Inc Sgc stimulatori
JP2016540017A (ja) 2013-12-11 2016-12-22 アイアンウッド ファーマシューティカルズ インコーポレイテッド ｓＧＣ刺激物質
EP3094327A1 (en) 2014-01-13 2016-11-23 Ironwood Pharmaceuticals, Inc. USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
WO2016044445A2 (en) 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
AU2015317824A1 (en) 2014-09-17 2017-03-23 Cyclerion Therapeutics, Inc. Pyrazole derivatives as sGC stimulators
CN107406421A (zh) 2014-09-17 2017-11-28 铁木医药有限公司 sGC刺激物
EP4420734A2 (en) 2015-02-13 2024-08-28 Institut National de la Santé et de la Recherche Médicale Ptgdr-1 and/or ptgdr-2 antagonists for preventing and/or treating systemic lupus erythematosus
AU2017291826B2 (en) 2016-07-07 2021-10-21 Cyclerion Therapeutics, Inc. Phosphorus prodrugs of sGC stimulators
KR20230074840A (ko) 2016-07-07 2023-05-31 사이클리온 테라퓨틱스, 인크. sGC 자극제의 고체 형태

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US4560343A (en) * 1984-06-11 1985-12-24 Honeywell Inc. Functional check for a hot surface ignitor element
JPS6149A (ja) * 1984-06-12 1986-01-06 Ono Pharmaceut Co Ltd 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤
CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
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Also Published As

Publication number Publication date
IL130660A0 (en) 2000-06-01
NZ336143A (en) 2002-05-31
CA2274591C (en) 2005-06-14
DE69715448T2 (de) 2003-08-07
CN1240438A (zh) 2000-01-05
CA2274591A1 (en) 1998-06-18
HUP0002869A3 (en) 2003-01-28
PT944614E (pt) 2003-01-31
AU5409798A (en) 1998-07-03
CN1185226C (zh) 2005-01-19
CZ206599A3 (cs) 1999-11-17
US6083974A (en) 2000-07-04
HUP0002869A2 (hu) 2001-06-28
KR20000069402A (ko) 2000-11-25
DE69715448D1 (de) 2002-10-17
JP2000514824A (ja) 2000-11-07
AR008939A1 (es) 2000-02-23
TR199901280T2 (xx) 1999-10-21
IL130660A (en) 2002-03-10
ES2181039T3 (es) 2003-02-16
PL191760B1 (pl) 2006-06-30
ATE223911T1 (de) 2002-09-15
JP3215441B2 (ja) 2001-10-09
DK0944614T3 (da) 2003-01-13
CN1445225A (zh) 2003-10-01
HK1020045A1 (en) 2000-03-10
PL334072A1 (en) 2000-01-31
BR9714016A (pt) 2000-02-29
KR100433568B1 (ko) 2004-05-31
EP0944614B1 (en) 2002-09-11
RU2161617C1 (ru) 2001-01-10
NO992838D0 (no) 1999-06-10
CN1105112C (zh) 2003-04-09
EP0944614A1 (en) 1999-09-29
TW438790B (en) 2001-06-07
AU718958B2 (en) 2000-05-04
CZ297324B6 (cs) 2006-11-15
WO1998025919A1 (en) 1998-06-18
NO992838L (no) 1999-07-20
HU226458B1 (en) 2008-12-29

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