HUT66162A - In 16-position quaternizated, substituted with amino-group androstane-derivatives and process for their production - Google Patents
In 16-position quaternizated, substituted with amino-group androstane-derivatives and process for their productionInfo
- Publication number
- HUT66162A HUT66162A HU9203436A HU9203436A HUT66162A HU T66162 A HUT66162 A HU T66162A HU 9203436 A HU9203436 A HU 9203436A HU 9203436 A HU9203436 A HU 9203436A HU T66162 A HUT66162 A HU T66162A
- Authority
- HU
- Hungary
- Prior art keywords
- substituted
- production
- derivatives
- quaternizated
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9203436A HU210076B (en) | 1992-11-02 | 1992-11-02 | Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them |
AU49005/93A AU665866B2 (en) | 1992-11-02 | 1993-10-14 | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
NZ248956A NZ248956A (en) | 1992-11-02 | 1993-10-14 | Androstane derivatives; preparation and pharmaceutical compositions |
CA002108741A CA2108741A1 (en) | 1992-11-02 | 1993-10-19 | Androstane derivatives substituted by a quaternary ammonium group in 16- position, pharmaceutical compositions containing them and process for preparing same |
IL10733193A IL107331A (en) | 1992-11-02 | 1993-10-20 | History of androstane converted to 61st place in a quarterly ammonium group, pharmaceutical mixtures containing them and process for their preparation |
UA93002174A UA27230C2 (uk) | 1992-11-02 | 1993-10-25 | Похідні андростану, заміщені по 16-му положенню четвертинною амонієвою групою, для використання як нервово-м'язових блокаторів та фармацевтична композиція, що здатна викликати нервово-м'язову блокаду |
JP5266920A JP2834651B2 (ja) | 1992-11-02 | 1993-10-26 | 16位が四級アンモニウム基で置換されたアンドロスタン誘導体、それを含有する医薬組成物およびそれらの製造法 |
US08/141,535 US5591735A (en) | 1992-11-02 | 1993-10-27 | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
DK93117558.2T DK0608495T3 (da) | 1992-11-02 | 1993-10-29 | Androstanderivater substitueret med en kvaternær ammoniumgruppe i 16-stillingen, farmaceutiske præparater indeholdende disse derivater og fremgangsmåde til deres fremstilling. |
ES93117558T ES2103413T3 (es) | 1992-11-02 | 1993-10-29 | Derivados del androstano sustituidos por un grupo amonio cuaternario en la posicion 16, composiciones farmaceuticas que los contienen y procedimientos para prepararlos. |
AT93117558T ATE154030T1 (de) | 1992-11-02 | 1993-10-29 | 16-(quaternär-ammoniak)-substituierte androstan- derivate, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung |
DE69311295T DE69311295T2 (de) | 1992-11-02 | 1993-10-29 | 16-(quaternär-Ammoniak)-substituierte Androstan-Derivate, pharmazeutische Präparate davon und ein Verfahren zu ihrer Herstellung |
RU93049598A RU2124021C1 (ru) | 1992-11-02 | 1993-10-29 | Производные андростана, замещенные по 16-положению четвертичной аммониевой группой, фармацевтическая композиция |
EP93117558A EP0608495B1 (en) | 1992-11-02 | 1993-10-29 | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
KR1019930023012A KR0179399B1 (ko) | 1992-11-02 | 1993-11-01 | 16-위치에 사차 암모늄기가 치환된 안드로스테인 유도체, 그를 함유하는 제약학적 조성물 및 그의 제조방법 |
CN93119822A CN1041937C (zh) | 1992-11-02 | 1993-11-02 | 雄甾烷衍生物及其药物组合物和制备方法 |
BR9304466A BR9304466A (pt) | 1992-11-02 | 1993-11-03 | Derivados do androstano, composiçao farmacêutica contendo esses derivados, processo para preparaçao dos mesmos, compostos intermediários, processo para preparaçao da dita composiçao e processo para bloquear a transmissao de impulsos nervosos (estímulos) a músculos estriados |
EE9400067A EE03073B1 (et) | 1992-11-02 | 1994-06-29 | Androstaani derivaadid, mis on 16. asendis asendatud kvaternaarse ammooniumrühmaga, neid sisaldavad farmatseutilised segud ja nende valmistamise protsess |
GR970401666T GR3024011T3 (en) | 1992-11-02 | 1997-07-08 | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9203436A HU210076B (en) | 1992-11-02 | 1992-11-02 | Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9203436D0 HU9203436D0 (en) | 1993-01-28 |
HUT66162A true HUT66162A (en) | 1994-09-28 |
HU210076B HU210076B (en) | 1995-01-30 |
Family
ID=10982503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9203436A HU210076B (en) | 1992-11-02 | 1992-11-02 | Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them |
Country Status (19)
Country | Link |
---|---|
US (1) | US5591735A (hu) |
EP (1) | EP0608495B1 (hu) |
JP (1) | JP2834651B2 (hu) |
KR (1) | KR0179399B1 (hu) |
CN (1) | CN1041937C (hu) |
AT (1) | ATE154030T1 (hu) |
AU (1) | AU665866B2 (hu) |
BR (1) | BR9304466A (hu) |
CA (1) | CA2108741A1 (hu) |
DE (1) | DE69311295T2 (hu) |
DK (1) | DK0608495T3 (hu) |
EE (1) | EE03073B1 (hu) |
ES (1) | ES2103413T3 (hu) |
GR (1) | GR3024011T3 (hu) |
HU (1) | HU210076B (hu) |
IL (1) | IL107331A (hu) |
NZ (1) | NZ248956A (hu) |
RU (1) | RU2124021C1 (hu) |
UA (1) | UA27230C2 (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020123928A1 (en) * | 2001-01-11 | 2002-09-05 | Eldering Charles A. | Targeting ads to subscribers based on privacy-protected subscriber profiles |
US7200804B1 (en) * | 1998-12-08 | 2007-04-03 | Yodlee.Com, Inc. | Method and apparatus for providing automation to an internet navigation application |
WO2001065453A1 (en) * | 2000-02-29 | 2001-09-07 | Expanse Networks, Inc. | Privacy-protected targeting system |
WO2007073424A1 (en) * | 2005-09-13 | 2007-06-28 | Sicor, Inc. | Pure rocuronium bromide |
CN102675402A (zh) * | 2012-05-16 | 2012-09-19 | 武汉大学 | 4,16β-二胺基甾体季铵盐衍生物及其制备方法和应用 |
CN109053855B (zh) * | 2018-10-08 | 2020-02-14 | 台州仙琚药业有限公司 | 一种16β-四氢吡咯基雄甾-2α-环氧-17-酮的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU165600B (hu) * | 1972-07-27 | 1974-09-28 | ||
US4177190A (en) * | 1975-08-01 | 1979-12-04 | Richter Gedeon Vegyeszeti Gyar Rt. | Diamino-androstanes and a process for the preparation of the said compounds |
DE2962627D1 (en) * | 1978-09-05 | 1982-06-09 | Akzo Nv | Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same |
GB8708886D0 (en) * | 1987-04-14 | 1987-05-20 | Akzo Nv | 2beta-morpholino-androstane derivatives |
GB8804579D0 (en) * | 1988-02-26 | 1988-03-30 | Akzo Nv | Novel 16-homo-piperidino-androstane derivatives & processes for their preparation |
-
1992
- 1992-11-02 HU HU9203436A patent/HU210076B/hu not_active IP Right Cessation
-
1993
- 1993-10-14 AU AU49005/93A patent/AU665866B2/en not_active Ceased
- 1993-10-14 NZ NZ248956A patent/NZ248956A/en unknown
- 1993-10-19 CA CA002108741A patent/CA2108741A1/en not_active Abandoned
- 1993-10-20 IL IL10733193A patent/IL107331A/en not_active IP Right Cessation
- 1993-10-25 UA UA93002174A patent/UA27230C2/uk unknown
- 1993-10-26 JP JP5266920A patent/JP2834651B2/ja not_active Expired - Fee Related
- 1993-10-27 US US08/141,535 patent/US5591735A/en not_active Expired - Fee Related
- 1993-10-29 DE DE69311295T patent/DE69311295T2/de not_active Expired - Fee Related
- 1993-10-29 DK DK93117558.2T patent/DK0608495T3/da active
- 1993-10-29 EP EP93117558A patent/EP0608495B1/en not_active Expired - Lifetime
- 1993-10-29 ES ES93117558T patent/ES2103413T3/es not_active Expired - Lifetime
- 1993-10-29 AT AT93117558T patent/ATE154030T1/de not_active IP Right Cessation
- 1993-10-29 RU RU93049598A patent/RU2124021C1/ru active
- 1993-11-01 KR KR1019930023012A patent/KR0179399B1/ko not_active IP Right Cessation
- 1993-11-02 CN CN93119822A patent/CN1041937C/zh not_active Expired - Fee Related
- 1993-11-03 BR BR9304466A patent/BR9304466A/pt not_active Application Discontinuation
-
1994
- 1994-06-29 EE EE9400067A patent/EE03073B1/xx not_active IP Right Cessation
-
1997
- 1997-07-08 GR GR970401666T patent/GR3024011T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH06192288A (ja) | 1994-07-12 |
ATE154030T1 (de) | 1997-06-15 |
DE69311295D1 (de) | 1997-07-10 |
EP0608495A3 (en) | 1995-12-20 |
KR0179399B1 (ko) | 1999-04-01 |
HU210076B (en) | 1995-01-30 |
HU9203436D0 (en) | 1993-01-28 |
EP0608495A2 (en) | 1994-08-03 |
US5591735A (en) | 1997-01-07 |
IL107331A (en) | 1998-12-06 |
UA27230C2 (uk) | 2000-08-15 |
ES2103413T3 (es) | 1997-09-16 |
DE69311295T2 (de) | 1997-10-30 |
EP0608495B1 (en) | 1997-06-04 |
CN1090852A (zh) | 1994-08-17 |
JP2834651B2 (ja) | 1998-12-09 |
NZ248956A (en) | 1995-08-28 |
CA2108741A1 (en) | 1994-05-03 |
AU665866B2 (en) | 1996-01-18 |
CN1041937C (zh) | 1999-02-03 |
KR940011476A (ko) | 1994-06-21 |
BR9304466A (pt) | 1994-06-14 |
IL107331A0 (en) | 1994-01-25 |
DK0608495T3 (da) | 1997-08-04 |
AU4900593A (en) | 1995-06-08 |
RU2124021C1 (ru) | 1998-12-27 |
GR3024011T3 (en) | 1997-10-31 |
EE03073B1 (et) | 1998-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HPC4 | Succession in title of patentee |
Owner name: RICHTER GEDEON VEGYESZETI GYAR RT., HU |
|
HC9A | Change of name, address |
Owner name: RICHTER GEDEON NYRT., HU Free format text: FORMER OWNER(S): RICHTER GEDEON VEGYESZETI GYAR RT., HU; DR. TUBA ZOLTAN, HU; DR. FOELDES F. FERENC, US; DR. VIZI E. SZILVESZTER, HU; MAHO SANDOR, HU |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |