ES2103413T3 - Derivados del androstano sustituidos por un grupo amonio cuaternario en la posicion 16, composiciones farmaceuticas que los contienen y procedimientos para prepararlos. - Google Patents
Derivados del androstano sustituidos por un grupo amonio cuaternario en la posicion 16, composiciones farmaceuticas que los contienen y procedimientos para prepararlos.Info
- Publication number
- ES2103413T3 ES2103413T3 ES93117558T ES93117558T ES2103413T3 ES 2103413 T3 ES2103413 T3 ES 2103413T3 ES 93117558 T ES93117558 T ES 93117558T ES 93117558 T ES93117558 T ES 93117558T ES 2103413 T3 ES2103413 T3 ES 2103413T3
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- quaternary ammonium
- ammonium group
- derivatives
- androstane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PRESENTAN NUEVOS DERIVADOS DEL ANDROSTANO ACTIVO TERAPEUTICAMENTE QUE TIENEN EFECTO DE BLOQUEO NEUROMUSCULAR, QUE ESTAN SUSTITUIDOS EN LA POSICION 16 POR UN GRUPO AMONIO CUATERNARIO. COMPOSICION FARMACEUTICA QUE LOS CONTIENE, PROCESOS PARA PRODUCIRLOS, Y NUEVOS INTERMEDIARIOS PARA LA PRODUCCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9203436A HU210076B (en) | 1992-11-02 | 1992-11-02 | Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2103413T3 true ES2103413T3 (es) | 1997-09-16 |
Family
ID=10982503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93117558T Expired - Lifetime ES2103413T3 (es) | 1992-11-02 | 1993-10-29 | Derivados del androstano sustituidos por un grupo amonio cuaternario en la posicion 16, composiciones farmaceuticas que los contienen y procedimientos para prepararlos. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5591735A (es) |
EP (1) | EP0608495B1 (es) |
JP (1) | JP2834651B2 (es) |
KR (1) | KR0179399B1 (es) |
CN (1) | CN1041937C (es) |
AT (1) | ATE154030T1 (es) |
AU (1) | AU665866B2 (es) |
BR (1) | BR9304466A (es) |
CA (1) | CA2108741A1 (es) |
DE (1) | DE69311295T2 (es) |
DK (1) | DK0608495T3 (es) |
EE (1) | EE03073B1 (es) |
ES (1) | ES2103413T3 (es) |
GR (1) | GR3024011T3 (es) |
HU (1) | HU210076B (es) |
IL (1) | IL107331A (es) |
NZ (1) | NZ248956A (es) |
RU (1) | RU2124021C1 (es) |
UA (1) | UA27230C2 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010049620A1 (en) * | 2000-02-29 | 2001-12-06 | Blasko John P. | Privacy-protected targeting system |
US20020123928A1 (en) * | 2001-01-11 | 2002-09-05 | Eldering Charles A. | Targeting ads to subscribers based on privacy-protected subscriber profiles |
US7200804B1 (en) * | 1998-12-08 | 2007-04-03 | Yodlee.Com, Inc. | Method and apparatus for providing automation to an internet navigation application |
TW200804409A (en) * | 2005-09-13 | 2008-01-16 | Sicor Inc | Processes for the synthesis of rocuronium bromide |
CN102675402A (zh) * | 2012-05-16 | 2012-09-19 | 武汉大学 | 4,16β-二胺基甾体季铵盐衍生物及其制备方法和应用 |
CN109053855B (zh) * | 2018-10-08 | 2020-02-14 | 台州仙琚药业有限公司 | 一种16β-四氢吡咯基雄甾-2α-环氧-17-酮的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU165600B (es) * | 1972-07-27 | 1974-09-28 | ||
US4177190A (en) * | 1975-08-01 | 1979-12-04 | Richter Gedeon Vegyeszeti Gyar Rt. | Diamino-androstanes and a process for the preparation of the said compounds |
DE2962627D1 (en) * | 1978-09-05 | 1982-06-09 | Akzo Nv | Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same |
GB8708886D0 (en) * | 1987-04-14 | 1987-05-20 | Akzo Nv | 2beta-morpholino-androstane derivatives |
GB8804579D0 (en) * | 1988-02-26 | 1988-03-30 | Akzo Nv | Novel 16-homo-piperidino-androstane derivatives & processes for their preparation |
-
1992
- 1992-11-02 HU HU9203436A patent/HU210076B/hu not_active IP Right Cessation
-
1993
- 1993-10-14 NZ NZ248956A patent/NZ248956A/en unknown
- 1993-10-14 AU AU49005/93A patent/AU665866B2/en not_active Ceased
- 1993-10-19 CA CA002108741A patent/CA2108741A1/en not_active Abandoned
- 1993-10-20 IL IL10733193A patent/IL107331A/en not_active IP Right Cessation
- 1993-10-25 UA UA93002174A patent/UA27230C2/uk unknown
- 1993-10-26 JP JP5266920A patent/JP2834651B2/ja not_active Expired - Fee Related
- 1993-10-27 US US08/141,535 patent/US5591735A/en not_active Expired - Fee Related
- 1993-10-29 RU RU93049598A patent/RU2124021C1/ru active
- 1993-10-29 AT AT93117558T patent/ATE154030T1/de not_active IP Right Cessation
- 1993-10-29 EP EP93117558A patent/EP0608495B1/en not_active Expired - Lifetime
- 1993-10-29 DE DE69311295T patent/DE69311295T2/de not_active Expired - Fee Related
- 1993-10-29 DK DK93117558.2T patent/DK0608495T3/da active
- 1993-10-29 ES ES93117558T patent/ES2103413T3/es not_active Expired - Lifetime
- 1993-11-01 KR KR1019930023012A patent/KR0179399B1/ko not_active IP Right Cessation
- 1993-11-02 CN CN93119822A patent/CN1041937C/zh not_active Expired - Fee Related
- 1993-11-03 BR BR9304466A patent/BR9304466A/pt not_active Application Discontinuation
-
1994
- 1994-06-29 EE EE9400067A patent/EE03073B1/xx not_active IP Right Cessation
-
1997
- 1997-07-08 GR GR970401666T patent/GR3024011T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2108741A1 (en) | 1994-05-03 |
CN1041937C (zh) | 1999-02-03 |
HU9203436D0 (en) | 1993-01-28 |
KR0179399B1 (ko) | 1999-04-01 |
JPH06192288A (ja) | 1994-07-12 |
GR3024011T3 (en) | 1997-10-31 |
BR9304466A (pt) | 1994-06-14 |
DE69311295T2 (de) | 1997-10-30 |
AU665866B2 (en) | 1996-01-18 |
DK0608495T3 (da) | 1997-08-04 |
DE69311295D1 (de) | 1997-07-10 |
EP0608495A3 (en) | 1995-12-20 |
EE03073B1 (et) | 1998-02-16 |
UA27230C2 (uk) | 2000-08-15 |
EP0608495A2 (en) | 1994-08-03 |
EP0608495B1 (en) | 1997-06-04 |
US5591735A (en) | 1997-01-07 |
JP2834651B2 (ja) | 1998-12-09 |
HU210076B (en) | 1995-01-30 |
RU2124021C1 (ru) | 1998-12-27 |
IL107331A (en) | 1998-12-06 |
NZ248956A (en) | 1995-08-28 |
IL107331A0 (en) | 1994-01-25 |
CN1090852A (zh) | 1994-08-17 |
AU4900593A (en) | 1995-06-08 |
HUT66162A (en) | 1994-09-28 |
ATE154030T1 (de) | 1997-06-15 |
KR940011476A (ko) | 1994-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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