HUP0401012A2 - Csökkentett IgE-reaktivitást mutató rovarméreg-allergének és eljárás előállításukra - Google Patents

Csökkentett IgE-reaktivitást mutató rovarméreg-allergének és eljárás előállításukra

Info

Publication number
HUP0401012A2
HUP0401012A2 HU0401012A HUP0401012A HUP0401012A2 HU P0401012 A2 HUP0401012 A2 HU P0401012A2 HU 0401012 A HU0401012 A HU 0401012A HU P0401012 A HUP0401012 A HU P0401012A HU P0401012 A2 HUP0401012 A2 HU P0401012A2
Authority
HU
Hungary
Prior art keywords
allergens
same
ige reactivity
reduced ige
producing
Prior art date
Application number
HU0401012A
Other languages
English (en)
Inventor
Oliver Cromwell
Helmut Fiebig
Roland Suck
Original Assignee
Merck Patent Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7931044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0401012(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh. filed Critical Merck Patent Gmbh.
Publication of HUP0401012A2 publication Critical patent/HUP0401012A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43568—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from wasps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány csökkentett IgE-reaktivitást mutató rekombinánsrovarméreg-allergénekre és előállítási eljárásukra vonatkozik. Azelőállítási eljárás körülményeitől függően a természetessel azonosvagy attól eltérő hajtogatódással rendelkező allergéneket kapnak. Atermészetestől eltérő hajtogatódással rendelkező allergénekcsökkentett IgE-reaktivitást, illetve allergenitást mutatnak, ígyallergiák immunterápiás kezelésére, míg a természetessel megegyezőhajtogatódással rendelkező allergének diagnosztikai célokraalkalmazhatók. Ó
HU0401012A 1999-12-01 2000-11-27 Csökkentett IgE-reaktivitást mutató rovarméreg-allergének és eljárás előállításukra HUP0401012A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19957904A DE19957904A1 (de) 1999-12-01 1999-12-01 Insektengift-Allergene mit verminderter IgE-Reaktivität und Verfahren zu ihrer Herstellung
PCT/EP2000/011776 WO2001040266A2 (de) 1999-12-01 2000-11-27 INSEKTENGIFT-ALLERGENE MIT VERMINDERTER IgE-REAKTIVITÄT UND VERFAHREN ZU IHRER HERSTELLUNG

Publications (1)

Publication Number Publication Date
HUP0401012A2 true HUP0401012A2 (hu) 2004-08-30

Family

ID=7931044

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401012A HUP0401012A2 (hu) 1999-12-01 2000-11-27 Csökkentett IgE-reaktivitást mutató rovarméreg-allergének és eljárás előállításukra

Country Status (15)

Country Link
US (2) US7285397B1 (hu)
EP (2) EP1512694B2 (hu)
JP (2) JP5597336B2 (hu)
CN (1) CN1205223C (hu)
AT (2) ATE339444T1 (hu)
AU (1) AU783505B2 (hu)
CA (1) CA2393975C (hu)
CZ (1) CZ20021874A3 (hu)
DE (3) DE19957904A1 (hu)
ES (2) ES2232518T3 (hu)
HU (1) HUP0401012A2 (hu)
PL (1) PL201904B1 (hu)
PT (2) PT1233984E (hu)
RU (1) RU2264462C2 (hu)
WO (1) WO2001040266A2 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19957904A1 (de) * 1999-12-01 2001-06-07 Merck Patent Gmbh Insektengift-Allergene mit verminderter IgE-Reaktivität und Verfahren zu ihrer Herstellung
JPWO2011033588A1 (ja) * 2009-09-18 2013-02-07 株式会社アドバンテスト 試験装置および試験方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2838800B2 (ja) * 1989-09-02 1998-12-16 株式会社林原生物化学研究所 減感作剤
DE4139000A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf
WO1994011512A2 (en) * 1992-11-12 1994-05-26 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
JP3578787B2 (ja) * 1993-05-14 2004-10-20 ラホヤ インスティチュート フォア アレルギー アンド イムノロジー 生物学的に活性なポリペプチドの組換え製造方法
US5804201A (en) * 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5
JP3288720B2 (ja) * 1996-06-11 2002-06-04 ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 変性タンパク質の活性化方法
WO1998028414A1 (en) * 1996-12-20 1998-07-02 Eli Lilly And Company Anti-obesity proteins
DE19957904A1 (de) † 1999-12-01 2001-06-07 Merck Patent Gmbh Insektengift-Allergene mit verminderter IgE-Reaktivität und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
CA2393975C (en) 2012-06-19
JP2004525601A (ja) 2004-08-26
EP1233984A2 (de) 2002-08-28
DE50013480D1 (de) 2006-10-26
ATE283284T1 (de) 2004-12-15
WO2001040266A3 (de) 2002-02-28
CZ20021874A3 (cs) 2002-08-14
WO2001040266A2 (de) 2001-06-07
PT1512694E (pt) 2007-01-31
JP5597336B2 (ja) 2014-10-01
AU2359401A (en) 2001-06-12
EP1233984B1 (de) 2004-11-24
JP5265745B2 (ja) 2013-08-14
PL355166A1 (en) 2004-04-05
EP1512694B1 (de) 2006-09-13
US7285397B1 (en) 2007-10-23
PL201904B1 (pl) 2009-05-29
ES2232518T3 (es) 2005-06-01
AU783505B2 (en) 2005-11-03
CN1451015A (zh) 2003-10-22
EP1512694B2 (de) 2010-11-03
CN1205223C (zh) 2005-06-08
DE19957904A1 (de) 2001-06-07
US20070280884A1 (en) 2007-12-06
ES2271764T3 (es) 2007-04-16
ATE339444T1 (de) 2006-10-15
EP1512694A1 (de) 2005-03-09
RU2264462C2 (ru) 2005-11-20
US8048424B2 (en) 2011-11-01
CA2393975A1 (en) 2001-06-07
JP2012087119A (ja) 2012-05-10
DE50008782D1 (de) 2004-12-30
ES2271764T5 (es) 2011-02-28
PT1233984E (pt) 2005-04-29

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